ChemicalBook > CAS DataBase List > Azido-PEG2-CH2CO2H

Azido-PEG2-CH2CO2H

Product Name
Azido-PEG2-CH2CO2H
CAS No.
882518-90-3
Chemical Name
Azido-PEG2-CH2CO2H
Synonyms
Azido-PEG2 AcOH;N3-PEG2-CH2COOH;AZIDE-PEG2-CH2COOH;Azido-PEG2-CH2COOH;Azido-PEG2-CH2CO2H;Azido-PEG2-CH2COOH,N3-PEG2-CH2COOH;(2-(2-Azidoethoxy)ethoxy)aceticacid;2-[2-(2-Azidoethoxy)ethoxy]acetic acid;Acetic acid, [2-(2-azidoethoxy)ethoxy]-;Acetic acid, 2-[2-(2-azidoethoxy)ethoxy]-
CBNumber
CB23062344
Molecular Formula
C6H11N3O4
Formula Weight
189.17
MOL File
882518-90-3.mol
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Azido-PEG2-CH2CO2H Property

storage temp. 
Storage temp. 2-8°C
solubility 
Soluble in Water
form 
Liquid
color 
Colorless to light yellow
InChI
InChI=1S/C6H11N3O4/c7-9-8-1-2-12-3-4-13-5-6(10)11/h1-5H2,(H,10,11)
InChIKey
OCIIYNXOTJRSHW-UHFFFAOYSA-N
SMILES
C(COCC(=O)O)OCCN=[N+]=[N-]
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A965943
Product name
Azido-PEG2-CH2CO2H
Packaging
10mg
Price
$90
Updated
2021/12/16
AK Scientific
Product number
AMTGC628
Product name
2-(2-(2-Azidoethoxy)ethoxy)aceticacid
Packaging
250mg
Price
$190
Updated
2021/12/16
Iris Biotech GmbH
Product number
PEG7950
Product name
N3-AEEA-OK
Packaging
25g
Price
$3240
Updated
2021/12/16
Acrotein
Product number
AC-8203
Product name
2-[2-(2-Azidoethoxy)ethoxy]aceticacid
Purity
97%
Packaging
0.25g
Price
$165
Updated
2021/12/16
Acrotein
Product number
AC-8203
Product name
2-[2-(2-Azidoethoxy)ethoxy]aceticacid
Purity
97%
Packaging
0.5g
Price
$247.5
Updated
2021/12/16
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Azido-PEG2-CH2CO2H Chemical Properties,Usage,Production

Description

Azido-PEG2-CH2CO2H is a water soluble click chemistry reagent containing an azide group with a terminal carboxylic acid. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Azido-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Azido-PEG2-CH2COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] Yimin Qian, et al. Composés et procédés pour la dégradation ciblée de protéines contenant un bromodomaine. WO2017030814A1.

Azido-PEG2-CH2CO2H Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Azido-PEG2-CH2CO2H manufacturers

Shanghai Joiny Pharmaceutical Co.,LTD
Product
2-[2-(2-Azidoethoxy)ethoxy]acetic acid 882518-90-3
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2025-05-07

882518-90-3, Azido-PEG2-CH2CO2HRelated Search:


  • Azido-PEG2-CH2CO2H
  • Azido-PEG2-CH2COOH
  • AZIDE-PEG2-CH2COOH
  • N3-PEG2-CH2COOH
  • 2-[2-(2-Azidoethoxy)ethoxy]acetic acid
  • N-(2-(2-(2-azidoethoxy)ethoxy))acetic acid
  • Acetic acid, [2-(2-azidoethoxy)ethoxy]-
  • Azido-PEG2-CH2COOH,N3-PEG2-CH2COOH
  • (2-(2-Azidoethoxy)ethoxy)aceticacid
  • Acetic acid, 2-[2-(2-azidoethoxy)ethoxy]-
  • Azido-PEG2 AcOH
  • 882518-90-3
  • peg