Azido-PEG2-CH2CO2H
- Product Name
- Azido-PEG2-CH2CO2H
- CAS No.
- 882518-90-3
- Chemical Name
- Azido-PEG2-CH2CO2H
- Synonyms
- Azido-PEG2 AcOH;N3-PEG2-CH2COOH;AZIDE-PEG2-CH2COOH;Azido-PEG2-CH2COOH;Azido-PEG2-CH2CO2H;Azido-PEG2-CH2COOH,N3-PEG2-CH2COOH;(2-(2-Azidoethoxy)ethoxy)aceticacid;2-[2-(2-Azidoethoxy)ethoxy]acetic acid;Acetic acid, [2-(2-azidoethoxy)ethoxy]-;Acetic acid, 2-[2-(2-azidoethoxy)ethoxy]-
- CBNumber
- CB23062344
- Molecular Formula
- C6H11N3O4
- Formula Weight
- 189.17
- MOL File
- 882518-90-3.mol
Azido-PEG2-CH2CO2H Property
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in Water
- form
- Liquid
- color
- Colorless to light yellow
- InChI
- InChI=1S/C6H11N3O4/c7-9-8-1-2-12-3-4-13-5-6(10)11/h1-5H2,(H,10,11)
- InChIKey
- OCIIYNXOTJRSHW-UHFFFAOYSA-N
- SMILES
- C(COCC(=O)O)OCCN=[N+]=[N-]
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A965943
- Product name
- Azido-PEG2-CH2CO2H
- Packaging
- 10mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- AMTGC628
- Product name
- 2-(2-(2-Azidoethoxy)ethoxy)aceticacid
- Packaging
- 250mg
- Price
- $190
- Updated
- 2021/12/16
- Product number
- PEG7950
- Product name
- N3-AEEA-OK
- Packaging
- 25g
- Price
- $3240
- Updated
- 2021/12/16
- Product number
- AC-8203
- Product name
- 2-[2-(2-Azidoethoxy)ethoxy]aceticacid
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $165
- Updated
- 2021/12/16
- Product number
- AC-8203
- Product name
- 2-[2-(2-Azidoethoxy)ethoxy]aceticacid
- Purity
- 97%
- Packaging
- 0.5g
- Price
- $247.5
- Updated
- 2021/12/16
Azido-PEG2-CH2CO2H Chemical Properties,Usage,Production
Description
Azido-PEG2-CH2CO2H is a water soluble click chemistry reagent containing an azide group with a terminal carboxylic acid. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Azido-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Azido-PEG2-CH2COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] Yimin Qian, et al. Composés et procédés pour la dégradation ciblée de protéines contenant un bromodomaine. WO2017030814A1.
Azido-PEG2-CH2CO2H Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Azido-PEG2-CH2CO2H manufacturers
- Product
- 2-[2-(2-Azidoethoxy)ethoxy]acetic acid 882518-90-3
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2025-05-07