4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate

Product Name: 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
CAS No.: 1577222-14-0
Chemical Name: 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
Synonyms: ALKS-8700;Diroximel Fumarete;diroximel fumarate;Diroximel Fumarete(ALKS-8700);Diroximel Fumarate DR Pellets;5-dioxopyrrolidin-1-yl)ethyl methyl fumarate;2-(2,5-Dioxopyrrolidin-1-yl)ethyl methyl fumarate;2-(2,5-Dioxopyrrolidin-1-Yl)Ethyl Methyl Fumarate(WXC04774);2-(2,5-dioxopyrrolidin-1-yl)ethyl (E)-4-chloro-4-oxobut-2-enoate;4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
CBNumber: CB23070732
Molecular Formula: C11H13NO6
Formula Weight: 255.22
MOL File: 1577222-14-0.mol

More

Less

4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate Property

Melting point:: 96 - 99°C
Boiling point:: 441.0±25.0 °C(Predicted)
Density: 1.319±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Ethyl Acetate (Slightly)
form: Solid
pka: -1.60±0.20(Predicted)
color: White to Off-White

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 29111
Product name: Diroximel Fumarate
Packaging: 5mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 29111
Product name: Diroximel Fumarate
Packaging: 50mg
Price: $553
Updated: 2024/03/01

Cayman Chemical

Product number: 29111
Product name: Diroximel Fumarate
Packaging: 10mg
Price: $143
Updated: 2024/03/01

Cayman Chemical

Product number: 29111
Product name: Diroximel Fumarate
Packaging: 25mg
Price: $336
Updated: 2024/03/01

AK Scientific

Product number: 6016DW
Product name: Diroximelfumarate
Packaging: 50mg
Price: $714
Updated: 2021/12/16

More

Less

4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate Chemical Properties,Usage,Production

Description

Diroximel fumarate is a prodrug form of monomethyl fumarate . It undergoes esterase cleavage in the gut to release monomethyl fumarate. Formulations containing diroximel fumarate have been used in the treatment of relapsing-remitting multiple sclerosis.

Uses

Diroximel Fumarate is a novel oral fumarate in development for the treatment of patients with relapsing forms of multiple sclerosis.

4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate Suppliers

China 76 India 9 Israel 1 United States 8 Global 94

Pharma Affiliates

Tel: --
Fax: --
Email: @pharmaffiliates.com
Country: India
ProdList: 6754
Advantage: 58

Triveni Interchem Private Limited (Group Of Triveni...

Tel: --
Fax: --
Country: India
ProdList: 497
Advantage: 58

Pharmaffiliates Analytics and Synthetics P. Ltd

Tel: --
Fax: --
Email: mktg@pharmaffiliates.com
Country: India
ProdList: 6739
Advantage: 58

SynZeal Research Pvt Ltd

Tel: --
Fax: --
Email: standards@synzeal.com
Country: India
ProdList: 6514
Advantage: 58

INTAS PHARMACEUTICALS LTD

Tel: --
Fax: --
Email: generalqueries@intaspharma.com
Country: India
ProdList: 33
Advantage: 58

CADILA HEALTHCARE LTD

Tel: --
Fax: --
Email: dhavalsoni@zyduscadila.com
Country: India
ProdList: 110
Advantage: 58

More

Less

View Lastest Price from 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate manufacturers

Career Henan Chemica Co

Product: 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate 1577222-14-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: MIn98%HPLC/LC
Supply Ability: 100KGS
Release date: 2020-10-29

1577222-14-0, 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioateRelated Search:

1-Methylpyrrolidine

(2E)-2-Butenedioic acid 1-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl] 4-methyl ester

2-(2,5-Dioxopyrrolidin-1-yl)ethyl methyl fumarate

Diroximel Fumarete

2-(2,5-Dioxopyrrolidin-1-Yl)Ethyl Methyl Fumarate(WXC04774)

4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate

ALKS-8700

diroximel fumarate

(E)-but-2-enedioic acid 2-(2,5-dioxo-pyrrolidin-1-yl)ethyl ester methyl ester

Diroximel Fumarete(ALKS-8700)

DIROXIMEL FUMARATE; ALKS8700; ALKS 8700; ALKS-8700;2-(2;5-DIOXOPYRROLIDIN-1-YL)ETHYL METHYL FUMARATE

5-dioxopyrrolidin-1-yl)ethyl methyl fumarate

2-Butenedioic acid (2E)-, 1-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl] 4-methyl ester

DiroximelFumarete,ALKS-8700,4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate

Diroximel Fumarate DR Pellets

Inhibitor,Diroximel,ALKS-8700,ALKS 8700,ALKS8700,BIIB 098,Diroximel fumarate,inhibit,BIIB098,BIIB-098

2-(2,5-dioxopyrrolidin-1-yl)ethyl (E)-4-chloro-4-oxobut-2-enoate

1577222-14-0

API