ChemicalBook > CAS DataBase List > PI4KIII beta inhibitor 1

PI4KIII beta inhibitor 1

Product Name
PI4KIII beta inhibitor 1
CAS No.
1881233-39-1
Chemical Name
PI4KIII beta inhibitor 1
Synonyms
PI4KIIIbeta-IN-10;PI4KIII beta inhibitor 1;PI4KIII beta inhibitor 10;N-(5-(3-(N-(4-HYDROXYPHENYL)SULFAMOYL)-4-METHOXYPHENYL)-4-METHYLTHIAZOL-2-YL)PIVALAMIDE;N-[5-[3-[(4-hydroxyphenyl)sulfamoyl]-4-methoxyphenyl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide;Propanamide, N-[5-[3-[[(4-hydroxyphenyl)amino]sulfonyl]-4-methoxyphenyl]-4-methyl-2-thiazolyl]-2,2-dimethyl-;inhibit,Phosphatidylinositol 4 kinases,Inhibitor,PI4 kinases,PI4K,PI4KIIIbetaIN10,PI-4KIIIbeta-IN-10,PI4KIIIbeta IN 10
CBNumber
CB23122932
Molecular Formula
C22H25N3O5S2
Formula Weight
475.58
MOL File
1881233-39-1.mol
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PI4KIII beta inhibitor 1 Property

Density 
1.367±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 30 mg/mL (63.08 mM)
form 
Solid
pka
9.06±0.10(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-5601
Product name
PI4KIIIbeta-IN-10
Purity
99.84%
Packaging
1mg
Price
$180
Updated
2021/12/16
ChemScene
Product number
CS-5601
Product name
PI4KIIIbeta-IN-10
Purity
99.84%
Packaging
5mg
Price
$420
Updated
2021/12/16
AK Scientific
Product number
9290DU
Product name
pi4KIIIbeta-IN-10
Packaging
1mg
Price
$441
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611434
Product name
PI4KIIIbeta-IN-10
Packaging
5mg
Price
$569.5
Updated
2021/12/16
ChemScene
Product number
CS-5601
Product name
PI4KIIIbeta-IN-10
Purity
99.84%
Packaging
10mg
Price
$660
Updated
2021/12/16
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PI4KIII beta inhibitor 1 Chemical Properties,Usage,Production

Biological Activity

PI4KIII beta inhibitor 1 is a potent PI4KIIIβ inhibitor with IC50 of 3.6 nM.

in vitro

PI4KIII beta inhibitor 1 is a potent PI4KIIIβ inhibitor with very minor off-target inhibition of PI4KIIIβ related lipid kinases. PI4KIIIbeta-IN-10 shows weak inhibition of PI3KC2γ (IC 50 < /sub> ~1 μM), PI3Kα (~10 μM), and PI4KIIIα (~3 μM), and <20% inhibition at concentrations up to 20 μM for PI4K2α, PI4K2β, and PI3Kβ.

target

PI4KIIIβ

3.6 nM (IC 50 )

PI4KIIIα

3 μM (IC 50 )

PI3Kδ

720 nM (IC 50 )

PI3KC2γ

1 μM ( IC 50 )

PI3Kα

10 μM (IC 50 )

PI3Kγ

20 μM (IC < sub> 50 )

PI4KIII beta inhibitor 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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PI4KIII beta inhibitor 1 Suppliers

China 35 United States 6 Global 41
Sichuan Wei Keqi Biological Technology Co., Ltd.
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1881233-39-1, PI4KIII beta inhibitor 1Related Search:

PI4KIIIbeta-IN-9

  • PI4KIII beta inhibitor 1
  • PI4KIIIbeta-IN-10
  • N-[5-[3-[(4-hydroxyphenyl)sulfamoyl]-4-methoxyphenyl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide
  • N-(5-(3-(N-(4-HYDROXYPHENYL)SULFAMOYL)-4-METHOXYPHENYL)-4-METHYLTHIAZOL-2-YL)PIVALAMIDE
  • Propanamide, N-[5-[3-[[(4-hydroxyphenyl)amino]sulfonyl]-4-methoxyphenyl]-4-methyl-2-thiazolyl]-2,2-dimethyl-
  • PI4KIII beta inhibitor 10
  • inhibit,Phosphatidylinositol 4 kinases,Inhibitor,PI4 kinases,PI4K,PI4KIIIbetaIN10,PI-4KIIIbeta-IN-10,PI4KIIIbeta IN 10
  • 1881233-39-1