PI4KIIIbeta-IN-9
- Product Name
- PI4KIIIbeta-IN-9
- CAS No.
- 1429624-84-9
- Chemical Name
- PI4KIIIbeta-IN-9
- Synonyms
- PI4KIIIβ-IN-9;PI4KIIIbeta-IN-9;PI4KIIIbeta inhibitor 9;PI4KIIIbeta-IN-9, 10 mM in DMSO;N-(5-(3-(N-(4-Hydroxyphenyl)sulfamoyl)-4-methoxyphenyl)-4-methylthiazol-2-yl)cyclopentanecarboxamide;Cyclopentanecarboxamide, N-[5-[3-[[(4-hydroxyphenyl)amino]sulfonyl]-4-methoxyphenyl]-4-methyl-2-thiazolyl]-;PI4 kinases,inhibit,Inhibitor,Phosphatidylinositol 4 kinases,PI4K,PI3K,PI4KIIIbetaIN9,Phosphoinositide 3-kinase,PI-4KIIIbeta-IN-9,PI4KIIIbeta IN 9
- CBNumber
- CB23126703
- Molecular Formula
- C23H25N3O5S2
- Formula Weight
- 487.59
- MOL File
- 1429624-84-9.mol
PI4KIIIbeta-IN-9 Property
- Density
- 1.421±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 8+-.0.70(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-5620
- Product name
- PI4KIIIbeta-IN-9
- Purity
- 99.01%
- Packaging
- 1mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- CS-5620
- Product name
- PI4KIIIbeta-IN-9
- Purity
- 99.01%
- Packaging
- 5mg
- Price
- $300
- Updated
- 2021/12/16
- Product number
- CS-5620
- Product name
- PI4KIIIbeta-IN-9
- Purity
- 99.01%
- Packaging
- 10mg
- Price
- $450
- Updated
- 2021/12/16
- Product number
- orb611408
- Product name
- PI4KIIIβ-IN-9
- Packaging
- 5mg
- Price
- $555.9
- Updated
- 2021/12/16
- Product number
- orb611408
- Product name
- PI4KIIIβ-IN-9
- Packaging
- 10mg
- Price
- $793.9
- Updated
- 2021/12/16
PI4KIIIbeta-IN-9 Chemical Properties,Usage,Production
Uses
PI4KIIIbeta-IN-9 is a potent PI4KIIIβ inhibitor with an IC50 of 7 nM. PI4KIIIbeta-IN-9 also inhibits PI3Kδ and PI3Kγ with IC50s of 152 nM and 1046 nM, respectively.
IC 50
PI4KIIIβ: 7 nM (IC50); PI4KIIIα: 2.6 μM (IC50); PI3Kδ: 152 nM (IC50); PI3Kγ: 1046 nM (IC50); PI3Kα: 2 μM (IC50); PI3KC2γ: 1 μM (IC50)
References
[1] Rutaganira FU, et al. Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ. J Med Chem. 2016 Mar 10;59(5):1830-9. DOI:10.1021/acs.jmedchem.5b01311
PI4KIIIbeta-IN-9 Preparation Products And Raw materials
Raw materials
Preparation Products
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