ChemicalBook > CAS DataBase List > PI4KIIIbeta-IN-9
PI4KIIIbeta-IN-9
- Product Name
- PI4KIIIbeta-IN-9
- CAS No.
- 1429624-84-9
- Chemical Name
- PI4KIIIbeta-IN-9
- Synonyms
- PI4KIIIβ-IN-9;PI4KIIIbeta-IN-9;PI4KIIIbeta inhibitor 9;PI4KIIIbeta-IN-9, 10 mM in DMSO;N-(5-(3-(N-(4-Hydroxyphenyl)sulfamoyl)-4-methoxyphenyl)-4-methylthiazol-2-yl)cyclopentanecarboxamide;Cyclopentanecarboxamide, N-[5-[3-[[(4-hydroxyphenyl)amino]sulfonyl]-4-methoxyphenyl]-4-methyl-2-thiazolyl]-;PI4 kinases,inhibit,Inhibitor,Phosphatidylinositol 4 kinases,PI4K,PI3K,PI4KIIIbetaIN9,Phosphoinositide 3-kinase,PI-4KIIIbeta-IN-9,PI4KIIIbeta IN 9
- CBNumber
- CB23126703
- Molecular Formula
- C23H25N3O5S2
- Formula Weight
- 487.59
- MOL File
- 1429624-84-9.mol
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PI4KIIIbeta-IN-9 Property
- Density
- 1.421±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 8?+-.0.70(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-5620
- Product name
- PI4KIIIbeta-IN-9
- Purity
- 99.01%
- Packaging
- 1mg
- Price
- $110
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-5620
- Product name
- PI4KIIIbeta-IN-9
- Purity
- 99.01%
- Packaging
- 5mg
- Price
- $300
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-5620
- Product name
- PI4KIIIbeta-IN-9
- Purity
- 99.01%
- Packaging
- 10mg
- Price
- $450
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb611408
- Product name
- PI4KIIIβ-IN-9
- Packaging
- 5mg
- Price
- $555.9
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb611408
- Product name
- PI4KIIIβ-IN-9
- Packaging
- 10mg
- Price
- $793.9
- Updated
- 2021/12/16
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PI4KIIIbeta-IN-9 Chemical Properties,Usage,Production
Uses
PI4KIIIbeta-IN-9 is a potent PI4KIIIβ inhibitor with an IC50 of 7 nM. PI4KIIIbeta-IN-9 also inhibits PI3Kδ and PI3Kγ with IC50s of 152 nM and 1046 nM, respectively.
IC 50
PI4KIIIβ: 7 nM (IC50); PI4KIIIα: 2.6 μM (IC50); PI3Kδ: 152 nM (IC50); PI3Kγ: 1046 nM (IC50); PI3Kα: 2 μM (IC50); PI3KC2γ: 1 μM (IC50)
References
[1] Rutaganira FU, et al. Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ. J Med Chem. 2016 Mar 10;59(5):1830-9. DOI:10.1021/acs.jmedchem.5b01311
PI4KIIIbeta-IN-9 Preparation Products And Raw materials
Raw materials
Preparation Products
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PI4KIIIbeta-IN-9 Suppliers
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