ChemicalBook > CAS DataBase List > dBET1
dBET1
- Product Name
- dBET1
- CAS No.
- 1799711-21-9
- Chemical Name
- dBET1
- Synonyms
- dBET1;CS-2706;DBET1;DBET-1 ;DBET 1;JQ1-Thalidomide conjugate;dBET1,inhibit,PROTACs,Epigenetic Reader Domain,Inhibitor,dBET 1,dBET-1;2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)acetamide;6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-[4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]butyl]-2,3,9-trimethyl-, (6S)-;N-(4-{2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0,2,6]trideca-2 (6),4,7,10,12-pentaen-9-yl]acetamido}butyl)-2-{[2-( 2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-i soindol-4-yl]oxy}acetamide
- CBNumber
- CB23133361
- Molecular Formula
- C38H37ClN8O7S
- Formula Weight
- 785.27
- MOL File
- 1799711-21-9.mol
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dBET1 Property
- Melting point:
- 186 - 187°C
- Density
- 1.55±0.1 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 10.68±0.40(Predicted)
- form
- Solid
- color
- Pale Yellow
- Stability:
- Hygroscopic
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Safety
- HS Code
- 2933998090
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 18044
- Product name
- dBET1
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 18044
- Product name
- dBET1
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $193
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 18044
- Product name
- dBET1
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $363
- Updated
- 2024/03/01
TRC
- Product number
- I120055
- Product name
- dBET1
- Packaging
- 2.5mg
- Price
- $855
- Updated
- 2021/12/16
TRC
- Product number
- I120055
- Product name
- dBET1
- Packaging
- 1mg
- Price
- $360
- Updated
- 2021/12/16
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dBET1 Chemical Properties,Usage,Production
Description
dBET1 is a PROTAC compound comprised of BET bromodomain antagonist (+)-JQ1 linked to a cereblon E3 ubiquitin ligase ligand.
Uses
dBET1 induces highly selective cereblon-dependent BET protein degradation in vitro and in vivo as well as delays leukemia progression in mice.
storage
Store at -20°C
dBET1 Preparation Products And Raw materials
Raw materials
Preparation Products
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dBET1 Suppliers
- Tel
- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
- ProdList
- 6393
- Advantage
- 58
- Tel
- +1 (732)236-3202
- sales@cckinase.com
- Country
- United States
- ProdList
- 2738
- Advantage
- 58
- Tel
- +1-+1(833)-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 57511
- Advantage
- 58
- Tel
- +1-781-999-5354
- support@targetmol.com
- Country
- United States
- ProdList
- 19973
- Advantage
- 58
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View Lastest Price from dBET1 manufacturers
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- dBET1 1799711-21-9
- Price
- US $0.00/mg
- Min. Order
- 1mg
- Purity
- 98%min
- Supply Ability
- 500mg
- Release date
- 2021-08-26
Career Henan Chemical Co
- Product
- dBET1 1799711-21-9
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-13