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N,N'-DICYCLOHEXYLUREA

Product Name
N,N'-DICYCLOHEXYLUREA
CAS No.
2387-23-7
Chemical Name
N,N'-DICYCLOHEXYLUREA
Synonyms
1,3-DICYCLOHEXYLUREA;Indapamide Impurity 1;Dicyclohexylcarbodiamide;NSC 30023;NSC 17013;AURORA KA-3582;Lomustine USP RC C;Lomustine Impurity C;N,N'-DICYCLOHEXYLUREA;n,n’-dicyclohexyl-ure
CBNumber
CB2314754
Molecular Formula
C13H24N2O
Formula Weight
224.34
MOL File
2387-23-7.mol
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N,N'-DICYCLOHEXYLUREA Property

Melting point:
232-233 °C(lit.)
Boiling point:
408℃
Density 
1.02
refractive index 
1.4832 (estimate)
Flash point:
158℃
storage temp. 
2-8°C
solubility 
DMSO (Slightly, Heated), Methanol (Slightly)
pka
13.89±0.20(Predicted)
form 
Liquid
color 
Clear
Stability:
Hygroscopic
InChI
InChI=1S/C13H24N2O/c16-13(14-11-7-3-1-4-8-11)15-12-9-5-2-6-10-12/h11-12H,1-10H2,(H2,14,15,16)
InChIKey
ADFXKUOMJKEIND-UHFFFAOYSA-N
SMILES
N(C1CCCCC1)C(NC1CCCCC1)=O
CAS DataBase Reference
2387-23-7(CAS DataBase Reference)
EPA Substance Registry System
N,N'-Dicyclohexylurea (2387-23-7)
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Safety

Hazard Codes 
Xn,N
Risk Statements 
22-51/53
Safety Statements 
61
WGK Germany 
3
TSCA 
Yes
HS Code 
29242100
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2924
Product name
Lomustine Related Compound C
Purity
certified reference material, pharmaceutical secondary standard
Packaging
500MG
Price
$575
Updated
2024/03/01
Sigma-Aldrich
Product number
D80800
Product name
N,N′-Dicyclohexylurea
Purity
98%
Packaging
25g
Price
$140
Updated
2024/03/01
Sigma-Aldrich
Product number
1369442
Product name
Lomustine Related Compound C
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
25mg
Price
$1500
Updated
2024/03/01
TCI Chemical
Product number
D0441
Product name
1,3-Dicyclohexylurea
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$37
Updated
2024/03/01
TCI Chemical
Product number
D0441
Product name
1,3-Dicyclohexylurea
Purity
>98.0%(GC)(T)
Packaging
500g
Price
$274
Updated
2024/03/01
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N,N'-DICYCLOHEXYLUREA Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

N,N''-Dicyclohexylurea,is a substituted Urea (U822500) compound, which has shown to be a potent inhibitor of juvenile hormone epoxide hydrolase (JHEH) of the tobacco hornworm M. sexta. Lomustine USP Related Compound C.

Definition

ChEBI: 1,3-dicyclohexylurea is a member of ureas.

Preparation

An excess of dry ice (200 g) was added gradually to a solution of dicyclohexylcarbodiimide (2.06 g, 0.01 mol), cyclohexylamine (1.98 g, 0.02 mol), and triethylamine (2.2 g, 0.02 mol) in THF at 75 ℃ over a period of 8 h. After stirring for 8 h, the reaction mixture was concentrated under reduced pressure and the resultant precipitate was collected. Fractional recrystallization of the precipitate from acetone/methanol gave N,N'-dicyclohexylurea; yield 2.2 g (98% based on dicyclohexylcarbodiimide and cyclohexylamine).

Synthesis Reference(s)

The Journal of Organic Chemistry, 61, p. 4175, 1996 DOI: 10.1021/jo9522825

N,N'-DICYCLOHEXYLUREA Preparation Products And Raw materials

Raw materials

Cyclohexylamine 3-Methyl-1-butanol

Preparation Products

Dicyclohexylcarbodiimide
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N,N'-DICYCLOHEXYLUREA Suppliers

Americas 1 Australia 1 Austria 1 Belgium 3 Canada 1 China 162 Europe 3 Germany 4 India 20 Japan 4 Russia 1 Slovakia 1 Switzerland 3 Ukraine 1 United Kingdom 9 United States 27 Global 242
Toronto Research Chemicals Inc.
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6668
Advantage
58
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View Lastest Price from N,N'-DICYCLOHEXYLUREA manufacturers

Hubei Lidu New Material Technology Co., Ltd
Product
N,N`-DICYCLOHEXYLUREA 2387-23-7
Price
US $0.00/g
Min. Order
1g
Purity
97%
Supply Ability
20tons
Release date
2024-09-19
Shaanxi Dideu New Materials Co. Ltd
Product
N,N''-Dicyclohexylurea 2387-23-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2024-11-14
Career Henan Chemical Co
Product
N,N'-DICYCLOHEXYLUREA 2387-23-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
25kg
Release date
2019-07-12

2387-23-7, N,N'-DICYCLOHEXYLUREARelated Search:

Docetaxel Metabolite M4 10-Oxo Docetaxel 2-Debenzoyl-2-pentenoyl Docetaxel (2S,4S,5R)-3-Boc-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic Acid Docetaxel Impurity 5 Docetaxel Impurity 36 (4S,5R)-3-(tert-Butoxycarbonyl)-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic acid R-Erythro-taxotere 4-Dichloroethoxy-carbonyl docetaxel Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-6-yl ester, (αR,βS... 7-Epi-docetaxel (Docetaxel Impurity C) UEXSQPKHDIPCHO-JVHVIAPCSA-N 10-Deacetylbaccatin III Docetaxel Impurity 6 Docetaxel Impurity 37 Cabazitaxel N-2 7-Methyl Docetaxel AOEGVETYSHPGBP-XYIDDFOTSA-N

  • AURORA KA-3582
  • n,n’-dicyclohexyl-ure
  • N,N'-DICYCLOHEXYLUREA
  • 1,3-DICYCLOHEXYLUREA
  • N,N,-Dicyclohexylurea98.%
  • Dicyclohexylcarbodiamide
  • N,N'-Carbonylbis(cyclohexanamine)
  • NSC 17013
  • NSC 30023
  • LoMustine Related CoMpound C
  • Lomustine EP Impurity B
  • 5-cyanobenzene-1,3-dicarboxylic acid
  • 1,3-Dicyclohexylurea for synthesis
  • Indapamide Impurity 1
  • 1,3-Dicyclohexylurea &gt
  • Lomustine USP RC C
  • Urea, N,N'-dicyclohexyl-
  • Lomustine Related Compound C (1,3-Dicyclohexylurea) (1369442)
  • Lomustine USP Related Compound C
  • Lomustine Impurity C
  • Lomustine EP Impurity C
  • Lomustine Impurity 3(Lomustine EP Impurity C)(Lomustine USP RC C)
  • 1,3-Dicyclohexylurea, ≥ 98.0%
  • n,n''-dicyclohexylurea
  • N,N'-DICYCLOHEXYLUREA
  • 1,3-dicyclohexylurea - impurity
  • 2387-23-7
  • C13H24N2O
  • C6H11NHCONHC6H11
  • Organic Building Blocks
  • Ureas
  • Building Blocks
  • Carbonyl Compounds
  • Finasteride
  • Carbonyl Compounds
  • Organic Building Blocks
  • Ureas