ChemicalBook > CAS DataBase List > 6-Acetyl-1,4-benzodioxane

6-Acetyl-1,4-benzodioxane

Product Name
6-Acetyl-1,4-benzodioxane
CAS No.
2879-20-1
Chemical Name
6-Acetyl-1,4-benzodioxane
Synonyms
AURORA 18707;ASISCHEM D29259;AKOS BBS-00006494;6-Acetylbenzodioxane;6-Acetyl-1,4-benzodixane;6-ACETYL-1,4-BENZODIOXANE;6-Acetyl-1,4-benzodioxane >6-Acetyl-1,4-benzodioxane-98%;3',4'-ETHYLENEDIOXYACETOPHENONE;1,4-BENZODIOXAN-6-YL METHYL KETONE
CBNumber
CB2315948
Molecular Formula
C10H10O3
Formula Weight
178.18
MOL File
2879-20-1.mol
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6-Acetyl-1,4-benzodioxane Property

Melting point:
80-82 °C (lit.)
Boiling point:
270.41°C (rough estimate)
Density 
1.1601 (rough estimate)
refractive index 
1.5370 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Fine Crystalline Needles
color 
Almost white to slightly blue
BRN 
164125
InChIKey
HGVWMTAIIYNQSI-UHFFFAOYSA-N
CAS DataBase Reference
2879-20-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Safety Statements 
24/25-25-24
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29145090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H260In contact with water releases flammable gases which may ignite spontaneously

H303May be harmfulif swallowed

H313May be harmful in contact with skin

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H331Toxic if inhaled

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P402+P404Store in a dry place. Store in a closed container.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
179027
Product name
1,4-Benzodioxan-6-yl methyl ketone
Purity
98%
Packaging
10g
Price
$84
Updated
2025/07/31
TCI Chemical
Product number
A1629
Product name
6-Acetyl-1,4-benzodioxane
Purity
>98.0%(GC)
Packaging
5g
Price
$61
Updated
2025/07/31
TRC
Product number
D454903
Product name
6-Acetylbenzodioxane
Packaging
100mg
Price
$75
Updated
2021/12/16
SynQuest Laboratories
Product number
2H17-1-39
Product name
1-(2,3-Dihydro-1,4-benzodioxin-6-yl)ethan-1-one
Packaging
10g
Price
$77
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK380765
Product name
1,4-Benzodioxan-6-yl methyl ketone
Purity
98%
Packaging
5g
Price
$61
Updated
2021/12/16
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6-Acetyl-1,4-benzodioxane Chemical Properties,Usage,Production

Chemical Properties

ALMOST WHITE TO SLIGHTLY BLUE FINE CRYST. NEEDLES

Uses

1,4-Benzodioxan-6-yl methyl ketone may be used in the preparation of acetylenic alcohols.

Definition

ChEBI: 1-(2,3-Dihydro-1,4-benzodioxin-6-yl)ethan-1-one is a benzodioxine.

Synthesis

7338-03-6

2879-20-1

GENERAL METHODS: Method B: To a stirred solution of 1-(2,3-dihydrobenzo[B][1,4]dioxin-6-yl)ethan-1-ol (4a, 1.65 g, 9.94 mmol) in anhydrous dichloromethane (100 mL) was added Dess-Martin's reagent (5.06 g, 11.93 mmol) at 0 °C and under argon protection. After 10 minutes of reaction, the mixture was slowly warmed to room temperature and stirring was continued for 16 hours. After completion of the reaction, the reaction was quenched with saturated sodium bicarbonate solution and filtered to remove the insoluble salt. The filtrate was extracted with dichloromethane, the combined organic layers were dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. Finally, the target product 6-acetyl-1,4-benzodioxane (5a, 1.42 g, 87% yield) was purified by silica gel column chromatography with dichloromethane as eluent to give a light yellow solid.

References

[1] European Journal of Medicinal Chemistry, 2015, vol. 105, p. 80 - 105

6-Acetyl-1,4-benzodioxane Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Acetyl-1,4-benzodioxane Suppliers

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View Lastest Price from 6-Acetyl-1,4-benzodioxane manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)ethanone 2879-20-1
Price
US $1.60-6.60/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-19
Zhuozhou Wenxi import and Export Co., Ltd
Product
1,4-Benzodioxan-6-yl Methyl ketone 2879-20-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
6-Acetyl-1,4-benzodioxane 2879-20-1
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-01

2879-20-1, 6-Acetyl-1,4-benzodioxaneRelated Search:

PIPERACETAZINE (250 MG) Paraquat dichloride Acetylferrocene Acetyl chloride Basic Violet 1 Acetonitrile Methylparaben Kresoxim-methyl 1,4-Dioxane Acetylacetone Methyl acetate Dihydromyrcenol N-ACETYL-L-TYROSINE ETHYL ESTER Methanol Methyl acrylate Methyl 6-CHLOROACETYL-1 4-BENZODIOXANE 97 tributyl acetocitrate

  • AURORA 18707
  • ASISCHEM D29259
  • 6-ACETYL-1,4-BENZODIOXANE
  • AKOS BBS-00006494
  • 3',4'-ETHYLENEDIOXYACETOPHENONE
  • 1-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)ETHAN-1-ONE
  • 1-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)ETHANONE
  • 1-(2,3-DIHYDROBENZO[B][1,4]DIOXIN-7-YL)ETHANONE
  • 1,4-BENZODIOXAN-6-YL METHYL KETONE
  • 1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethan-1-one 98%
  • JRH-03502, 1-(2,3-Dihydrobenzo[b][1,4]dioxin-7-yl)ethanone, 97%
  • 1,4-Benzodioxan-6-yl methyl ketone~3,4-Ethylenedioxyacetophenone
  • 1-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-ethanone
  • Ethanone, 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-
  • 6-Acetyl-2,3-dihydro-1,4-benzodioxin
  • 1,4-Benzodioxan-6-yl methyl ketone,98%
  • (E)-5-(4-hydroxystyryl)benzene-1,3-diol
  • 1-(2,3-dihydro-1,4-benzodioxin-7-yl)ethanone
  • 6-Acetyl-1,4-benzodixane
  • 6-Acetyl-1,4-benzodioxane &gt
  • 6-Acetylbenzodioxane
  • 6-Acetyl-1,4-benzodioxane-98%
  • 6-Acetyl-1,4-benzodioxane, ≥ 98.0%
  • 2879-20-1
  • Benzodioxanes
  • Building Blocks
  • Heterocyclic Building Blocks
  • BenzodioxanesCarbonyl Compounds
  • Building Blocks
  • C10
  • Heterocyclic Building Blocks
  • Ketones