N-(m-PEG4)-N'-(azide-PEG3)-Cy5
- Product Name
- N-(m-PEG4)-N'-(azide-PEG3)-Cy5
- CAS No.
- 2107273-02-7
- Chemical Name
- N-(m-PEG4)-N'-(azide-PEG3)-Cy5
- Synonyms
- N-(m-PEG4)-N'-(azide-PEG3)-Cy5
- CBNumber
- CB23163047
- Molecular Formula
- C42H60ClN5O7
- Formula Weight
- 782.42
- MOL File
- 2107273-02-7.mol
N-(m-PEG4)-N'-(azide-PEG3)-Cy5 Property
- solubility
- Soluble in Water, DMSO, DMF, DCM
N-Bromosuccinimide Price
- Product number
- BP-23003
- Product name
- N-(m-PEG4)-N'-(azide-PEG3)-Cy5
- Purity
- 97%
- Packaging
- 1mg
- Price
- $150
- Updated
- 2021/12/16
N-(m-PEG4)-N'-(azide-PEG3)-Cy5 Chemical Properties,Usage,Production
Description
N-(m-PEG4)-N'-(azide-PEG3)-Cy5 is a PEG linker containing a cyanine dye with excitation/emmission maximum 649/667 nm as well as an azide group, which enables Click Chemistry. The hydophilic PEG spacer increases solubility in aqueous media.
Uses
N-(m-PEG4)-N'-(azide-PEG3)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(m-PEG4)-N'-(azide-PEG3)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-(m-PEG4)-N'-(azide-PEG3)-Cy5 Preparation Products And Raw materials
Raw materials
Preparation Products
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