Equol
- Product Name
- Equol
- CAS No.
- 531-95-3
- Chemical Name
- Equol
- Synonyms
- Equol;(S)-EQUOL;R,S-EQUOL;S,R-equol;(3S)-Equol;(-)-(S)-EQUOL;Equol USP/EP/BP;EQUOL, (+/-)-(SH);(S)-Equol,99%e.e.;4',7-ISOFLAVANDIOL
- CBNumber
- CB2317528
- Molecular Formula
- C15H14O3
- Formula Weight
- 242.27
- MOL File
- 531-95-3.mol
Equol Property
- Melting point:
- 189-190°C
- alpha
- D -21.5°
- Boiling point:
- 312.25°C (rough estimate)
- Density
- 1.1914 (rough estimate)
- refractive index
- 1.5557 (estimate)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- DMSO (Soluble), Ethanol (Slightly), Methanol (Slightly)
- pka
- 9.94±0.40(Predicted)
- form
- Solid
- color
- White to Pale Yellow
- CAS DataBase Reference
- 531-95-3(CAS DataBase Reference)
Safety
- WGK Germany
- 3
- F
- 3-10
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 10010173
- Product name
- (S)-Equol
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $21
- Updated
- 2024/03/01
- Product number
- 10010173
- Product name
- (S)-Equol
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $89
- Updated
- 2024/03/01
- Product number
- 10010173
- Product name
- (S)-Equol
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $157
- Updated
- 2024/03/01
- Product number
- 10010173
- Product name
- (S)-Equol
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $341
- Updated
- 2024/03/01
- Product number
- 6158
- Product name
- (S)-Equol
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $122
- Updated
- 2021/12/16
Equol Chemical Properties,Usage,Production
Chemical Properties
White to Off-White Solid
Uses
Receptor; binding activity
Uses
A human urinary metabolite of Daidzein. It is also a natural estrogenic metabolite from soy isoflavones
Uses
serine protease
Uses
(S)-Equol and R-Equol are metabolites of the soy isoflavones Daidzein (D103500) and Genistein. Both have significant biological actions.
Definition
ChEBI: Equol is a member of hydroxyisoflavans.
Biological Activity
equol is an isoflavan produced by intestinal bacteria in response to soy isoflavone intake in human. it shows a wide range of activities including antioxidant activity, anti-inflammation activity and anticancer activity. it is reported that equol specifically binds to 5α-dht and has a modest affinity for recombinant estrogen receptor erβ, which may be responsible for most of equol’s biological properties. [1]
in vitro
in vitro studies were conducted to measure both the binding affinity of equol for 5alpha-dihydrotestosterone (5alpha-dht) and the effects of equol treatment in human prostate cancer (lncap) cells. it was found that equol bound to 5alpha-dht with maximum and half maxim concentrations of 100 nm and 4.8 nm, respectively. in addition, equol significantly offset the increases in psa levels from lncap cells. [1]
in vivo
an in vivo study was performed to investigate effects of equol on rat prostate weight and circulating levels of sex steroid hormones. 1.0 mg/kg of equol was injected to long-evans rats fed with a low isoflavone diet for 25 days. findings from this study suggested that equol significantly decreased rat prostate weights and down-regulated serum levels of 5alpha-dht. however, this agent did not alter levels of lh, testosterone and estradiol. [1]
References
[1]lund td, blake c, bu l, hamaker an, lephart ed. iequol an isoflavonoid: potential for improved prostate health, in vitro and in vivo evidence. reprod biol endocrin. 2011; 9(4): doi: 10.1186/1477-7827-9-4.
[2]setchell dr and clerici c. equol: pharmacokinetics and biological actions. j nutr. 2010 jul; 140(7): 1363s–8s.
Equol Preparation Products And Raw materials
Raw materials
Preparation Products
Equol Suppliers
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View Lastest Price from Equol manufacturers
- Product
- Equol; Soybean extract 531-95-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- >99% HPLC
- Supply Ability
- 1000KG
- Release date
- 2022-09-16
- Product
- Equol 531-95-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 50000kg
- Release date
- 2023-09-19
- Product
- Equol 531-95-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2 tons
- Release date
- 2022-12-06