ChemicalBook > CAS DataBase List > 2-Propenoic acid, 3,3'-(1,3-phenylene)bis-
2-Propenoic acid, 3,3'-(1,3-phenylene)bis-
- Product Name
- 2-Propenoic acid, 3,3'-(1,3-phenylene)bis-
- CAS No.
- 37710-81-9
- Chemical Name
- 2-Propenoic acid, 3,3'-(1,3-phenylene)bis-
- Synonyms
- TC AQP1 1;m-Benzenediacrylic acid;m-Phenylenediacrylic acid;TC-AQP-1-1,TCAQP11,TC AQP1 1;3,3'-(1,3-Phenylene)diacrylic acid;2-Propenoic acid, 3,3'-(1,3-phenylene)bis-;2-Propenoic acid, 3,3'-(1,3-phenylene)bis-
- CBNumber
- CB23207516
- Molecular Formula
- C12H10O4
- Formula Weight
- 218.21
- MOL File
- 37710-81-9.mol
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2-Propenoic acid, 3,3'-(1,3-phenylene)bis- Property
- Boiling point:
- 458.7±33.0 °C(Predicted)
- Density
- 1.358±0.06 g/cm3(Predicted)
- storage temp.
- RT
- solubility
- Soluble in DMSO (up to 25 mg/ml).
- form
- solid
- pka
- 4.07±0.10(Predicted)
- color
- White
- Stability:
- Stable for 1 year from date of pruchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
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N-Bromosuccinimide Price
Tocris
- Product number
- 5412
- Product name
- TCAQP11
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $106
- Updated
- 2021/12/16
Tocris
- Product number
- 5412
- Product name
- TCAQP11
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $445
- Updated
- 2021/12/16
TRC
- Product number
- T120105
- Product name
- TCAQP11
- Packaging
- 10mg
- Price
- $100
- Updated
- 2021/12/16
Usbiological
- Product number
- 256822
- Product name
- TC AQP1 1
- Packaging
- 10mg
- Price
- $339
- Updated
- 2021/12/16
Atlantic Research Chemicals
- Product number
- CA001841
- Product name
- 3-[3-(2-Carboxyeth-1-en-1-yl)phenyl]prop-2-enoicacid
- Purity
- 95%
- Packaging
- 1gm:
- Price
- $420.61
- Updated
- 2021/12/16
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2-Propenoic acid, 3,3'-(1,3-phenylene)bis- Chemical Properties,Usage,Production
Description
CVPA (37710-81-9) is an aquaporin-1 inhibitor (IC50 = 8.1 μM) discovered by molecular docking against the extracellular domain of human aquaporin-1 followed by experimental testing in a Xenopus oocyte swelling assay.1
Uses
TC AQP1 1 is a human aquaoporin-1 (hAQP1) selective inhibitor and is considered to have therapeutic potential towards the potential treatment of glaucoma, brain edema, inflammatory pain and certain types of cancer.
storage
Store at +4°C
References
1) Seeliger et al. (2012), Discovery of novel human aquaporin-1 blockers; ACS Chem. Biol., 8 249
2-Propenoic acid, 3,3'-(1,3-phenylene)bis- Preparation Products And Raw materials
Raw materials
Preparation Products
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2-Propenoic acid, 3,3'-(1,3-phenylene)bis- Suppliers
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