Boc-3,3-Diphenyl-L-alanine

Product Name: Boc-3,3-Diphenyl-L-alanine
CAS No.: 138662-63-2
Chemical Name: Boc-3,3-Diphenyl-L-alanine
Synonyms: BOC-L-3;BOC-ALA(3;BOC-DPH-OH;Boc-Dip-OH;Boc-L-Dip-OH;3-DIPHENYL)-OH;3-Diphenylalanine;Boc-beta-phenyl-OH;boc-β-phenyl-phe-oh;RARECHEM BK PT 0194
CBNumber: CB2321600
Molecular Formula: C20H23NO4
Formula Weight: 341.4
MOL File: 138662-63-2.mol

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Boc-3,3-Diphenyl-L-alanine Property

Melting point:: 160 °C (dec.)(lit.)
alpha: 29 º (c=1 in chloroform)
Boiling point:: 502.7±50.0 °C(Predicted)
Density: 1.167±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
pka: 3.68±0.10(Predicted)
form: solid
color: White
BRN: 4880641
CAS DataBase Reference: 138662-63-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2922498590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 09896
Product name: Boc-β-phenyl-Phe-OH
Purity: ≥98.0% (TLC)
Packaging: 1g
Price: $179
Updated: 2025/07/31

Usbiological

Product number: 264336
Product name: Boc-L-3-
Packaging: 1g
Price: $360
Updated: 2021/12/16

Usbiological

Product number: 264940
Product name: Boc-3,3-diphenyl-L-alanine
Packaging: 500mg
Price: $333
Updated: 2021/12/16

Activate Scientific

Product number: AS85417
Product name: Boc-3,3-Diphenyl-L-alanine
Purity: 95+% ee
Packaging: 5G
Price: $354
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB48023
Product name: Boc-3,3-diphenyl-L-alanine
Packaging: 10g
Price: $325
Updated: 2021/12/16

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Boc-3,3-Diphenyl-L-alanine Chemical Properties,Usage,Production

Uses

Boc-L-3,3-diphenylalanine, is an alanine derivative used in chemical synthesis and peptide chemistry.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

24424-99-5

138662-63-2

Example 5 Synthesis of L-2-tert-butoxycarbonylamino-3,3-diphenylpropionic acid: L-2-amino-3,3-diphenylpropionic acid (0.10 g, 0.28 mmol, 92.9% ee) was dissolved in water, and the pH was adjusted to 8-9 with sodium bicarbonate. ethyl acetate (1.0 mL) and di-tert-butyl dicarbonate (0.1 g, 0.45 mmol) were added and the reaction mixture was stirred at 37°C for 16 hours. Upon completion of the reaction, it was cooled to room temperature, the pH was adjusted to 2 with 6N hydrochloric acid, and partition extraction was performed to transfer N-tert-butoxycarbonyl-3-phenyl-L-phenylalanine to the organic layer. The organic layer was concentrated and heptane was added to the residue and stirred overnight to promote crystallization. The crystals were collected by filtration and dried to give N-Boc-3-phenyl-L-phenylalanine (97% ee, chiral column SUMICHIRAL OA-4100, mobile phase: hexane: methanol: 2-propanol: trifluoroacetic acid = 98:1:1:0.1, detection wavelength 220 nm, flow rate 1.0 mL/min, room temperature).

References

[1] Patent: EP1724253, 2006, A2. Location in patent: Page/Page column 22

Boc-3,3-Diphenyl-L-alanine Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-3,3-Diphenyl-L-alanine Suppliers

China 120 Europe 3 France 2 Germany 3 India 3 Japan 2 South Korea 1 Switzerland 1 United Kingdom 7 United States 27 Global 169

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View Lastest Price from Boc-3,3-Diphenyl-L-alanine manufacturers

Career Henan Chemical Co

Product: N-(tert-Butoxycarbonyl)-beta-phenyl-L-phenylalanine 138662-63-2
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: as request
Release date: 2018-12-24

138662-63-2, Boc-3,3-Diphenyl-L-alanineRelated Search:

FMoc-(2S,3R)-2-aMino-3-hydroxy-4,4-diMethylpentanoic acid (2R,3S)-2-aMino-3-hydroxy-4,4-diMethylpentanoic acid L-Phenylalanine 3,3-Diphenylpropionic acid N-Boc-beta-phenyl-L-phenylalaninol 3,3-Diphenyl-L-alanine Boc-3,3-Diphenyl-L-alanine 3,3-Diphenylpropanol N-(TERT-BUTOXYCARBONYL)-BETA-PHENYL-D-PHENYLALANINE (R)-1,1-DIPHENYL-2-AMINOPROPANE (S)-DIPHENYLALANINOL (S)-2-AMINO-3-PHENYL-BUTYRIC ACID 2-AMINO-3-PHENYL-BUTYRIC ACID 2-AMINO-3,3-DIPHENYL-PROPIONIC ACID (2S,3R)-N-BOC-2-AMINO-3-PHENYLBUTYRIC ACID, 95%, (98% E.E.) 2-BOC-AMINO-3,3-DIPHENYL PROPIONIC ACID N-BOC-ERYTHRO-DL-BETA-METHYLPHENYLALANINE,99% BOC-(S)-ALPHA-BENZHYDRYL-PROLINE

boc-β-phenyl-phe-oh

n-(tert-butoxycarbonyl)-β-phenyl-l-phenylalanine

3,3-Diphenyl-L-alanine, N-BOC protected

(S)-2-(tert-butoxycarbonylamino)-3,3-diphenylpropanoic acid

N-Boc-β-phenyl-L-phenylalanine

(S)-N-Boc-2-amino-3,3-diphenylpropionic acid

Boc-L-Dip-OH

Boc-L-3,3-Diphenyl-Ala-OH

BOC-β-phenyl-L-phenylalanine

Boc-β,β-diphenyl-Ala-OH, Boc-3,3-diphenyl-L-alanine, N-(tert-Butoxycarbonyl)-β-phenyl-L-phenylalanine

BOC-L-3

N-Boc-3,3-diphenyl-L-alanine, 95%

Boc-(S)-2-aMino-3,3-diphenylpropanoic acid

(2s)-2-[(2-Methylpropan-2-yl)oxycarbonylaMino]-3,3-diphenylpropanoic Acid

(S)-N-(tert-Butoxycarbonyl)-β-phenyl-phenylalanine

Boc-3,3-diphenyl-L-alanine99%

Boc-L-Ala(3,3-diphenyl)-OH

L-PHENYLALANINE,N-[(1,1-DIMETHYLETHOXY)CARBONYL]-B-PHENYL-

(2S)-2-[(tert-butoxycarbonyl)aMino]-3,3-diphenylpropanoic acid

BOC-(3-PHENYL)PHE-OH

BOC-3,3-DIPHENYL-L-ALANINE

BOC-ALA(3,3-DIPHENYL)-OH

BOC-BETA-PHENYL-L-PHENYLALANINE

BOC-BETA-PHENYL-PHE-OH

BOC-BETA BETA-DIPHENYL-ALA-OH

BOC-L-3,3-DIPHENYLALANINE

BOC-DPH-OH

(S)-N-(TERT-BUTOXYCARBONYL)-BETA-PHENYL-PHENYLALANINE

RARECHEM BK PT 0194

N-(TERT-BUTOXYCARBONYL)-BETA-PHENYL-L-PHENYLALANINE

N-BOC-BETA-PHENYL-L-PHENYLALANINE

N-ALPHA-T-BUTOXYCARBONYL-L-3,3-DIPHENYLALANINE

N-(tert-Butoxycarbonyl)-3-phenyl-L-phenylalanine

Boc-beta-phenyl-OH

(Tert-Butoxy)Carbonyl L-3,3-Diphenylalanine

N-Boc-β-phenyl-L-phenylalani

BOC-ALA(3

(Tert-Butoxy)Carbonyl L-3

3-DIPHENYL)-OH

3-Diphenylalanine

N-[(1,1-Dimethylethoxy)carbonyl]-β-phenyl-L-phenylalanine

2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3,3-diphenylpropanoic acid

Boc-Beta-phenyl-Phe-OH, ≥98.0%

L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-β-phenyl-

N-Boc-3,3-diphenyl-L-alanine,95%

(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3,3-diphenylpropanoicaci

N-(tert-Butoxycarbonyl)-beta-phenyl-L-phenylalanine USP/EP/BP

Boc-β-phenyl-Phe-OH, CAS 138662-63-2

Boc-Dip-OH

138662-63-2

C10H23NO4

C6H52CHCHNHCO2CCH33CO2H

C65H82N6O18

Peptide Synthesis

Phenylalanine

Specialty Synthesis

Unnatural Amino Acid Derivatives

Amino Acid Derivatives