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D-2-Aminobutyric acid

Product Name
D-2-Aminobutyric acid
CAS No.
2623-91-8
Chemical Name
D-2-Aminobutyric acid
Synonyms
(R)-2-aminobutanoic acid;R-AMINOBUTYRIC ACID;H-D-ABU-OH;(R)-(-)-2-AMINOBUTYRIC ACID;D-2-Abu;H-D-Aib-OH;D-Butyrine;H-D-2-ABU-OH;H-D-ABU(2)-OH;D-ETHYLGLYCINE
CBNumber
CB2322157
Molecular Formula
C4H9NO2
Formula Weight
103.12
MOL File
2623-91-8.mol
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D-2-Aminobutyric acid Property

Melting point:
>300 °C (lit.)
alpha 
-21.2 º (c=2, 6N HCl)
Boiling point:
215.2±23.0 °C(Predicted)
Density 
1.2300 (estimate)
refractive index 
1.4650 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble
form 
Crystalline Powder
pka
2.34±0.10(Predicted)
color 
White
optical activity
[α]20/D 21 to 19°, c = 4 in H2O
Water Solubility 
soluble
BRN 
1720934
Major Application
peptide synthesis
InChI
1S/C4H9NO2/c1-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m1/s1
InChIKey
QWCKQJZIFLGMSD-GSVOUGTGSA-N
SMILES
CC[C@@H](N)C(O)=O
LogP
-0.064 (est)
CAS DataBase Reference
2623-91-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Safety Statements 
22-24/25
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29224999
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
116122
Product name
D-2-Aminobutyric acid
Purity
98%
Packaging
1g
Price
$25.55
Updated
2025/07/31
Sigma-Aldrich
Product number
116122
Product name
D-2-Aminobutyric acid
Purity
98%
Packaging
5g
Price
$57.9
Updated
2025/07/31
TCI Chemical
Product number
A1377
Product name
(R)-(-)-2-Aminobutyric Acid
Purity
>98.0%(T)
Packaging
1g
Price
$19
Updated
2025/07/31
TCI Chemical
Product number
A1377
Product name
(R)-(-)-2-Aminobutyric Acid
Purity
>98.0%(T)
Packaging
5g
Price
$52
Updated
2025/07/31
TRC
Product number
A602915
Product name
(R)-(-)-2-Aminobutyric Acid
Packaging
1g
Price
$45
Updated
2021/12/16
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D-2-Aminobutyric acid Chemical Properties,Usage,Production

Chemical Properties

WHITE CRYSTALLINE POWDER

Uses

(R)-2-Aminobutyric Acid is an isomer of L-Aminobutyric Acid (A602930) which is a receptor antagonist.

Definition

ChEBI: D-alpha-aminobutyric acid is an optically active form of alpha-aminobutyric acid having D-configuration. It is an alpha-aminobutyric acid and a D-alpha-amino acid. It is an enantiomer of a L-alpha-aminobutyric acid.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

Currently, the methods reported in the literature for the synthesis of D-2-aminobutyric acid such as the synthesis of D-2-aminobutyric acid from D-configuration methionine by desulfurization and other steps; ammonification and hydrolysis reaction method of butyronic acid, and chemical disassembly method. First, the racemic 2-aminobutyric acid is acetylated to obtain N-acetyl-2-aminobutyric acid, and then the aminoacylase extracted from pig kidney is used to selectively hydrolyze off the (S)-configuration N-acetyl-2-aminobutyric acid to obtain the (S)-2-aminobutyric acid, and the (R)-N-acetyl-2-aminobutyric acid which is not hydrolyzed is subjected to the racemic treatment by an appropriate method to obtain racemic 2-aminobutyric acid, thus realizing the dynamic of its 2-aminobutanoic acid. Aminobutyric acid, thus realizing its dynamic kinetic splitting and achieving a final yield of 71.9%.

IC 50

Microbial Metabolite; Human Endogenous Metabolite

D-2-Aminobutyric acid Preparation Products And Raw materials

Raw materials

Preparation Products

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D-2-Aminobutyric acid Suppliers

Taizhou Tianhong Biochemistry Technology Co., Ltd.
Tel
0523-86132544 15366717810
Fax
0523-86201489
Email
sales@thbiochem.com
Country
China
ProdList
377
Advantage
55
Shanghai SE Pharm Co., Ltd
Tel
18112588827
Email
sales4@sepharm.com.cn
Country
China
ProdList
285
Advantage
60
Wuxi Jingyao Bio-Technology Co., Ltd.
Tel
88770633 13961738808
Email
jingyaobiotech@126.com
Country
China
ProdList
349
Advantage
55
Huanggang Senyang Chemical Co., LTD
Tel
713-8205211 17671088222
Email
413248427@qq.com
Country
China
ProdList
193
Advantage
58
Nanjing Redwood Fine Chemical Co., Ltd.
Tel
158-05183379 15805183379
Fax
86-025-58905816
Email
zjp@redwood.com.cn
Country
China
ProdList
217
Advantage
60
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6003
Advantage
61
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View Lastest Price from D-2-Aminobutyric acid manufacturers

R&D Scientific Inc.
Product
D-(-)-2-Aminobutyric acid 2623-91-8
Price
US $350.00/Kg
Min. Order
0.100Kg
Purity
99 %
Supply Ability
5000 Kg
Release date
2025-06-01
Zhuozhou Wenxi import and Export Co., Ltd
Product
D(-)-2-Aminobutyric acid 2623-91-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
D(-)-2-Aminobutyric acid 2623-91-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

2623-91-8, D-2-Aminobutyric acidRelated Search:


  • R-AMINOBUTYRIC ACID
  • (R)-(-)-2-AMINO-N-BUTYRIC ACID
  • (R) 2-AMINOBUTYRIC ACID
  • (R)-(-)-2-AMINOBUTYRIC ACID
  • D-A-AMINO-N-BUTYRIC ACID
  • D-ALPHA-AMINO-BUTYRIC ACID
  • D-ALPHA-AMINO-N-BUTYRIC ACID
  • D-ETHYLGLYCINE
  • H-D-NHCH(CH2CH3)-COOH
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  • H-D-ABU(2)-OH
  • H-D-ABU(ALPHA)-OH
  • H-D-ABU-OH
  • D-2-AMINO-BUTANOIC ACID
  • D-(-)-2-AMINOBUTYRIC ACID
  • D-2-AMINOBUTYRIC ACID
  • D-(-)-2-AMINO-N-BUTYRIC ACID
  • D-2-AMINO-N-BUTYRIC ACID
  • D-2-Aminobutyric acid;(R)-(-)-2-Aminobutyric acid
  • D-α-Amino-butyric acid
  • (R)-2-aminobutanoic acid
  • D-A-AMINO-N-BUTYRIC ACID CRYSTALLINE
  • D(-)-2-Aminobutyric acid, 99+%
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  • D-(-)-2-Aminobutyric acid, 98+%
  • (-)-D-Butyrine
  • D-Butyrine
  • D-2-Aminobutyric aci
  • D-Aminobutyric acid amide
  • (2R)-2-aMinobutanoic acid
  • D-(-)-2-Aminobutyric acid, (2R)-(-)-Aminobutyric acid
  • Butanoic acid, 2-aMino-, (R)-
  • Butyric acid, 2-aMino-, D- (8CI)
  • D-α-Aminobutyric acid≥ 99% (Assay)
  • )-2-Aminobutyric acid H-D-Abu-OH D-Aminobutyric acid amide
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  • Glutamic Acid Impurity 11 ((R)-2-Aminobutyric Acid)
  • D-2-Aminobutyric acid,(R)-2-aminobutanoic acid
  • Avanafil Impurity 85
  • <sc>D</sc>-2-Aminobutyric acid
  • 2623-91-8
  • 2632-91-8
  • C2H5CHNH2CO2H
  • C4H9NO2
  • Alanine Derivatives
  • Peptide Synthesis
  • Unnatural Amino Acid Derivatives
  • Specialty Synthesis
  • AMINE
  • Unusual Amino Acids
  • Pharmaceutical Intermediates