GS 39783

Product Name: GS 39783
CAS No.: 39069-52-8
Chemical Name: GS 39783
Synonyms: GS 39783;N,N'-DICYCLOPENTYL-2-(METHYLTHIO)-5-NITRO-4,6-PYRIMIDINEDIAMINE;N4,N6-Dicyclopentyl-2-(methylthio)-5-nitropyrimidine-4,6-diamine;N,N'-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediaamine;4,6-Pyrimidinediamine, N4,N6-dicyclopentyl-2-(methylthio)-5-nitro-;N,N'-DICYCLOPENTYL-2-METHYLSULFANYL-5-NITRO-PYRIMIDINE-4,6-DIAMINE
CBNumber: CB2323806
Molecular Formula: C15H23N5O2S
Formula Weight: 337.44
MOL File: 39069-52-8.mol

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GS 39783 Property

storage temp.: Store at RT
solubility: DMSO: ~8 mg/mL
form: powder
color: yellow

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1520
Product name: GS39783
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $95.7
Updated: 2022/05/15

Sigma-Aldrich

Product number: SML1520
Product name: GS39783
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $386
Updated: 2022/05/15

Cayman Chemical

Product number: 29482
Product name: GS-39783
Packaging: 5mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 29482
Product name: GS-39783
Packaging: 10mg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 29482
Product name: GS-39783
Packaging: 25mg
Price: $286
Updated: 2024/03/01

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GS 39783 Chemical Properties,Usage,Production

Uses

GS 39783 is an allosteric positive modulator of GABAB receptors. GS 39783 attenuates acute cocaine-induced hyperlocomotion and blocks cocaine-induced Fos induction in the striatal complex.

Definition

ChEBI: N4,N6-dicyclopentyl-2-(methylthio)-5-nitropyrimidine-4,6-diamine is an aryl sulfide.

Biological Activity

Novel positive allosteric modulator of GABA B receptor function. Potentiates the effects of GABA on [ 35 S]GTP γ S binding at recombinant and native GABA B receptors (EC 50 values are 2.1 and 3.1 μ M respectively). Decreases cocaine self-administration, blocks the rewarding properties of nicotine and produces anxiolytic-like activity without the side effects associated with baclofen or benzodiazepines.

storage

Store at RT

GS 39783 Preparation Products And Raw materials

Raw materials

Preparation Products

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GS 39783 Suppliers

Canada 1 China 29 Germany 2 India 1 Japan 1 Switzerland 1 United Kingdom 1 United States 8 Global 44

Toronto Research Chemicals

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39069-52-8, GS 39783Related Search:

GS 39783 4,5-DIAMINO-2-MERCAPTOPYRIMIDINE 4,6-Diamino-5-Nitro-2-Thiolpyrimidine 4,6-DIAMINO-5-NITROPYRIMIDINE 2-MERCAPTO-4,5,6-TRIAMINOPYRIMIDINE 4,6-DIAMINO-2-MERCAPTO-5-NITROSOPYRIMIDINE

N,N'-DICYCLOPENTYL-2-METHYLSULFANYL-5-NITRO-PYRIMIDINE-4,6-DIAMINE

N,N'-DICYCLOPENTYL-2-(METHYLTHIO)-5-NITRO-4,6-PYRIMIDINEDIAMINE

GS 39783

N,N'-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediaamine

N4,N6-Dicyclopentyl-2-(methylthio)-5-nitropyrimidine-4,6-diamine

4,6-Pyrimidinediamine, N4,N6-dicyclopentyl-2-(methylthio)-5-nitro-

39069-52-8

GABA/Glycine receptor