ETHYL 1-METHYL-5-NITROIMIDAZOLE-2-CARBOXYLATE
- Product Name
- ETHYL 1-METHYL-5-NITROIMIDAZOLE-2-CARBOXYLATE
- CAS No.
- 1564-49-4
- Chemical Name
- ETHYL 1-METHYL-5-NITROIMIDAZOLE-2-CARBOXYLATE
- Synonyms
- AKOS 92999;ETHYL 1-METHYL-5-NITROIMIDAZOLE-2-CARBOXYLATE;Ethyl 1-Methyl-5-nitro-1H-iMidazole-2-carboxylate;ethyl 1-methyl-5-nitro-imidazole-2-carboxylate - [E83254];1H-Imidazole-2-carboxylic acid, 1-methyl-5-nitro-, ethyl ester
- CBNumber
- CB2325330
- Molecular Formula
- C7H9N3O4
- Formula Weight
- 199.16
- MOL File
- Mol file
ETHYL 1-METHYL-5-NITROIMIDAZOLE-2-CARBOXYLATE Property
- Melting point:
- 81-83°C
- Boiling point:
- 350.7±34.0 °C(Predicted)
- Density
- 1.42±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- -0.95±0.25(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- E946000
- Product name
- Ethyl1-methyl-5-nitro-1H-imidazole-2-carboxylate
- Packaging
- 100mg
- Price
- $265
- Updated
- 2021/12/16
- Product number
- 7841AA
- Product name
- Ethyl1-methyl-5-nitro-1H-imidazole-2-carboxylate
- Packaging
- 1g
- Price
- $485
- Updated
- 2021/12/16
- Product number
- CHM0303033
- Product name
- ETHYL 1-METHYL-5-NITROIMIDAZOLE-2-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.01
- Updated
- 2021/12/16
- Product number
- CM122459
- Product name
- ethyl1-methyl-5-nitro-1H-imidazole-2-carboxylate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $546
- Updated
- 2021/12/16
- Product number
- CM122459
- Product name
- ethyl1-methyl-5-nitro-1H-imidazole-2-carboxylate
- Purity
- 95+%
- Packaging
- 5g
- Price
- $1547
- Updated
- 2021/12/16
ETHYL 1-METHYL-5-NITROIMIDAZOLE-2-CARBOXYLATE Chemical Properties,Usage,Production
Synthesis
30148-21-1
1564-49-4
Step 6a. ethyl 1-methyl-1H-imidazole-2-carboxylate (2.0 g, 13 mmol) was dissolved in 8 mL of concentrated H2SO4, followed by the slow addition of 8 mL of concentrated HNO3. The reaction mixture was stirred at 70 °C for 3 h. The reaction mixture was then extracted with dichloromethane (DCM). After completion of the reaction, the solution was diluted with H2O and the pH was adjusted to 7-8 with aqueous Na2CO3. The reaction mixture was extracted with dichloromethane (DCM) and the organic layers were combined and concentrated. Purification by silica gel column chromatography (eluent: ethyl acetate/petroleum ether) afforded the target compound 1-methyl-5-nitro-1H-imidazole-2-carboxylic acid ethyl ester as a yellow solid (0.9 g, 34.7% yield).ESI-MS m/z = 200.20 [M + H]+.
References
[1] Patent: WO2016/183266, 2016, A1. Location in patent: Page/Page column 50
ETHYL 1-METHYL-5-NITROIMIDAZOLE-2-CARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
ETHYL 1-METHYL-5-NITROIMIDAZOLE-2-CARBOXYLATE Suppliers
- Tel
- --
- Fax
- --
- akos@akosgmbh.de
- Country
- Germany
- ProdList
- 6717
- Advantage
- 72