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tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate

Product Name
tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate
CAS No.
1383133-23-0
Chemical Name
tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate
Synonyms
Hsp90-IN-37;tert-Butyl 2-aminobenzimidazole-1-carboxylate;tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate;1H-Benzimidazole-1-carboxylic acid, 2-amino-, 1,1-dimethylethyl ester
CBNumber
CB23308820
Molecular Formula
C12H15N3O2
Formula Weight
233.27
MOL File
1383133-23-0.mol
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tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate Property

Boiling point:
388.1±25.0 °C(Predicted)
Density 
1.24±0.1 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
pka
4.28±0.10(Predicted)
form 
Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Ambeed
Product number
A843847
Product name
tert-Butyl2-amino-1H-benzo[d]imidazole-1-carboxylate
Purity
95%
Packaging
100mg
Price
$207
Updated
2021/12/16
Ambeed
Product number
A843847
Product name
tert-Butyl2-amino-1H-benzo[d]imidazole-1-carboxylate
Purity
95%
Packaging
250mg
Price
$309
Updated
2021/12/16
Ambeed
Product number
A843847
Product name
tert-Butyl2-amino-1H-benzo[d]imidazole-1-carboxylate
Purity
95%
Packaging
1g
Price
$772
Updated
2021/12/16
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tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate Chemical Properties,Usage,Production

Uses

Hsp90-IN-37 (Z-2) is a heat shock protein 90 (Hsp90) inhibitor that inhibits Hsp90 enzymatic activity by 69%. Hsp90-IN-37 has antitumor activity[1].

References

[1] Abbasi M, et al. Identification of New Hsp90 Inhibitors: Structure Based Virtual Screening, Molecular Dynamic Simulation, Synthesis and Biological Evaluation. Anticancer Agents Med Chem. 2021;21(18):2583-2591. DOI:10.2174/1871520621666210201101818

tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate Suppliers

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1383133-23-0, tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylateRelated Search:


  • tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate
  • 1H-Benzimidazole-1-carboxylic acid, 2-amino-, 1,1-dimethylethyl ester
  • tert-Butyl 2-aminobenzimidazole-1-carboxylate
  • Hsp90-IN-37
  • 1383133-23-0