1-Boc-4-(4-fluoro-phenylamino)-piperidine
- Product Name
- 1-Boc-4-(4-fluoro-phenylamino)-piperidine
- CAS No.
- 288573-56-8
- Chemical Name
- 1-Boc-4-(4-fluoro-phenylamino)-piperidine
- Synonyms
- tert-butyl 4-(4-fluoroanilino)piperidine-1-carboxylate;KS0037;Pharmaceutical Powder;tert-Butyl 4-(4-fluoroanilino)-1-;1-Piperidinecarboxylicacid CAS 288573-56-8;High purity 4-[(4-fluorophenyl)amino]- CAS 288573-56-8;KS-0037 powder;1,1-dimethylethyl ester CAS 288573-56-8;1-Boc-4- (4-fluorophenamide) -piperidine;1-BOC-4-(4-FLUORO-PHENYLAMINO)-PIPERIDINE
- CBNumber
- CB3280285
- Molecular Formula
- C16H23FN2O2
- Formula Weight
- 294.36
- MOL File
- 288573-56-8.mol
1-Boc-4-(4-fluoro-phenylamino)-piperidine Property
- Boiling point:
- 400.4±40.0 °C(Predicted)
- Density
- 1.159±0.06 g/cm3(Predicted)
- pka
- 5.09±0.20(Predicted)
- InChI
- InChI=1S/C16H23FN2O2/c1-16(2,3)21-15(20)19-10-8-14(9-11-19)18-13-6-4-12(17)5-7-13/h4-7,14,18H,8-11H2,1-3H3
- InChIKey
- TUYSUNKDSSHKHM-UHFFFAOYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CCC(NC2=CC=C(F)C=C2)CC1
N-Bromosuccinimide Price
- Product number
- HCH0049921
- Product name
- 1-BOC-4-(4-FLUORO-PHENYLAMINO)-PIPERIDINE
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $586.97
- Updated
- 2021/12/16
- Product number
- HCH0049921
- Product name
- 1-BOC-4-(4-FLUORO-PHENYLAMINO)-PIPERIDINE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $618.5
- Updated
- 2021/12/16
- Product number
- HCH0049921
- Product name
- 1-BOC-4-(4-FLUORO-PHENYLAMINO)-PIPERIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $623.82
- Updated
- 2021/12/16
- Product number
- SC-58847
- Product name
- 1-Boc-4-(4-Fluoro-phenylamino)-piperidine
- Purity
- 95
- Packaging
- 5g
- Price
- $1833
- Updated
- 2021/12/16
1-Boc-4-(4-fluoro-phenylamino)-piperidine Chemical Properties,Usage,Production
Chemical Properties
1-Boc-4-(4-Fluoro-Phenylamino)-Piperidine (Tert-Butyl 4- (4-fluoroanilino) Piperidine-1-Carboxylate) is a white solid.
Uses
1-Boc-4-(4-fluoro-phenylamino)-piperidine (Tert-Butyl 4- (4-fluoroanilino) Piperidine-1-Carboxylate) is a heterocyclic derivative and can be used as a pharmaceutical intermediate.
Preparation
Sodium cyanoborohydride (661 mg, 10.0 mmol) was added to a methylene chloride solution (30 ml) of t-butyl 4-oxopiperidine-1-carboxylate (2.66 g, 13.1 mmol), 4-fluoroaniline (1.46 g, 13.1 mmol) and acetic acid (0.750 ml, 13.1 mmol), at 0°C, and stirring was carried out at room temperature for 15 hours. A saturated aqueous sodium hydrogencarbonate solution was added to the reaction solution, followed by extraction with ethyl acetate, and the extract was washed sequentially with water and saline, and dried over anhydrous sodium sulfate. The organic layer was concentrated and the resulting residue was washed with diisopropyl ether, followed by drying to afford 1-Boc-4-(4-Fluoro-Phenylamino)-Piperidine. Yield 80%.
1-Boc-4-(4-fluoro-phenylamino)-piperidine Preparation Products And Raw materials
Raw materials
Preparation Products
1-Boc-4-(4-fluoro-phenylamino)-piperidine Suppliers
View Lastest Price from 1-Boc-4-(4-fluoro-phenylamino)-piperidine manufacturers
- Product
- ks-0037, 1-BOC-4-(4-fluorophenylamine)-piperidine 288573-56-8
- Price
- US $620.00/kg
- Min. Order
- 0.1kg
- Purity
- 99%
- Supply Ability
- 10ton
- Release date
- 2024-05-28