ChemicalBook > CAS DataBase List > Apalutamide Acid Impurity
Apalutamide Acid Impurity
- Product Name
- Apalutamide Acid Impurity
- CAS No.
- 1332391-04-4
- Chemical Name
- Apalutamide Acid Impurity
- Synonyms
- AP-COOH;APLA-COOH;APT-api-imF;Apalutamide-COOH;Apatamide impurity 2;Apalutamide impurity 01;Apalutamide Acid Impurity;Apalutamide Impurity 1 Sodium Salt;4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3,4]octan-5-yl)-2-fluorobenzoic acid;Benzoic acid, 4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-
- CBNumber
- CB23312856
- Molecular Formula
- C20H12F4N4O3S
- Formula Weight
- 464.39
- MOL File
- 1332391-04-4.mol
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Apalutamide Acid Impurity Property
- Boiling point:
- 661.7±65.0 °C(Predicted)
- Density
- 1.69±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- form
- Solid
- pka
- 2.81±0.10(Predicted)
- color
- White to off-white
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Apalutamide Acid Impurity Chemical Properties,Usage,Production
Uses
Apalutamide-COOH is a metabolite of Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1].
References
[1] Nicholas D. Smith, et al. Androgen receptor modulators and uses thereof. WO2011103202A2.
Apalutamide Acid Impurity Preparation Products And Raw materials
Raw materials
Preparation Products
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