ChemicalBook > CAS DataBase List > CEP-28122 monomesilate hydrochloride salt
CEP-28122 monomesilate hydrochloride salt
- Product Name
- CEP-28122 monomesilate hydrochloride salt
- CAS No.
- 1354545-57-5
- Chemical Name
- CEP-28122 monomesilate hydrochloride salt
- Synonyms
- CEP-28122 MS SALT;CEP-28122 Mesylate;CEP-28122 mesylate hydrochloride;CEP-28122 monomesilate hydrochloride salt;(1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide methanesulfonate;(1S,2S,3R,4R)-3-((5-Chloro-2-(((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino)pyrimidin-4-yl)amino)bicyclo[2.2.1]hept-5-ene-2-carboxamide methanesulfonate hydrochloride
- CBNumber
- CB23339866
- Molecular Formula
- C29H40Cl2N6O6S
- Formula Weight
- 671.6355
- MOL File
- 1354545-57-5.mol
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N-Bromosuccinimide Price
AK Scientific
- Product number
- SYN5737
- Product name
- CEP-28122Mesylate
- Packaging
- 100mg
- Price
- $1843
- Updated
- 2021/12/16
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CEP-28122 monomesilate hydrochloride salt Chemical Properties,Usage,Production
Uses
CEP-28122 mesylate hydrochloride is a diaminopyrimidine derivative.CEP-28122 mesylate hydrochloride is a potent, selective, and orally bioavailable ALK inhibitor with an IC50 of 1.9 nM. CEP-28122 mesylate hydrochloride has antitumor and good pharmacokinetic activity[1].
References
[1] Mangeng Cheng, et al. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. Mol Cancer Ther. 2012 Mar;11(3):670-9. DOI:10.1158/1535-7163.MCT-11-0776
CEP-28122 monomesilate hydrochloride salt Preparation Products And Raw materials
Raw materials
Preparation Products
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1354545-57-5, CEP-28122 monomesilate hydrochloride saltRelated Search:
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