MANOOL
- Product Name
- MANOOL
- CAS No.
- 596-85-0
- Chemical Name
- MANOOL
- Synonyms
- MANOOL;Nsc165961;Manool (80%);(13R)-Labda-8(17),14-diene-13-ol;Labda-8(20),14-dien-13-ol, (13R)-;[13R,(+)]-Labda-8(17),14-dien-13-ol;[13R,(+)]-Labda-8(17),14-diene-13-ol;4ARTRANS-5-(-TETRAME-2-METHYLENEDECAHYDR;5-(5,5,8a-Trimethyl-2-methylenedecahydro-1-naphthalenyl)-3-methyl-1-penten-3-ol;(αR,1S,4aS,8aS)-α-Ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-1-napthalenepropanol
- CBNumber
- CB2334659
- Molecular Formula
- C20H34O
- Formula Weight
- 290.48
- MOL File
- 596-85-0.mol
MANOOL Property
- Melting point:
- 49-52 °C(lit.)
- Boiling point:
- 150-153 °C(Press: 0.3 Torr)
- Density
- 0.93±0.1 g/cm3(Predicted)
- Flash point:
- >230 °F
- storage temp.
- 4°C, stored under nitroge
- solubility
- Benzene (Slightly), Chloroform (Slightly), Methanol (Slightly)
- form
- Low-Melting Solid
- pka
- 14.47±0.29(Predicted)
- color
- White to Off-White
- Specific Gravity
- 0.97
- Odor
- Very delicate, woody, dry-sweet, and extremely tenacious odor
- LogP
- 6.790 (est)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H400Very toxic to aquatic life
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- E678100
- Product name
- Manool(80%)
- Packaging
- 100mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- FM65852
- Product name
- Manool
- Packaging
- 50mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- FM65852
- Product name
- Manool
- Packaging
- 100mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- 9756AJ
- Product name
- Manool
- Packaging
- 50mg
- Price
- $218
- Updated
- 2021/12/16
- Product number
- API0003252
- Product name
- MANOOL
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $329.7
- Updated
- 2021/12/16
MANOOL Chemical Properties,Usage,Production
Uses
Maintains anti-proliferative activity against human malignant cell strains.
Definition
ChEBI: A labdane diterpenoid in which the labdane skeleton has double bonds at positions 8(17) and 14 and carries an R-hydroxy group at position 13.
Preparation
By extraction of cornrninuted wood of Dacrydium biforme, a tree indigenous to New Zealand, with alcohol or Acetone. The extract is neutralized with alkali, and the crude Manool may be recrystallized.
Cytotoxicity
IC50 (μg/mL): 49.3 (V79), 15.6 (B16F10),17.1 (MCF-7), 6.7 (HeLa), 28.5 (HepG2),9.6 (MO59 J), 6.7 (U343), 13.1 (U251)(de Oliveira et al. 2016)
MANOOL Preparation Products And Raw materials
Raw materials
Preparation Products
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