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MANOOL

Product Name
MANOOL
CAS No.
596-85-0
Chemical Name
MANOOL
Synonyms
MANOOL;Nsc165961;Manool (80%);(13R)-Labda-8(17),14-diene-13-ol;Labda-8(20),14-dien-13-ol, (13R)-;[13R,(+)]-Labda-8(17),14-dien-13-ol;[13R,(+)]-Labda-8(17),14-diene-13-ol;4ARTRANS-5-(-TETRAME-2-METHYLENEDECAHYDR;5-(5,5,8a-Trimethyl-2-methylenedecahydro-1-naphthalenyl)-3-methyl-1-penten-3-ol;(αR,1S,4aS,8aS)-α-Ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-1-napthalenepropanol
CBNumber
CB2334659
Molecular Formula
C20H34O
Formula Weight
290.48
MOL File
596-85-0.mol
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MANOOL Property

Melting point:
49-52 °C(lit.)
Boiling point:
150-153 °C(Press: 0.3 Torr)
Density 
0.93±0.1 g/cm3(Predicted)
Flash point:
>230 °F
storage temp. 
4°C, stored under nitroge
solubility 
Benzene (Slightly), Chloroform (Slightly), Methanol (Slightly)
form 
Low-Melting Solid
pka
14.47±0.29(Predicted)
color 
White to Off-White
Specific Gravity
0.97
Odor
Very delicate, woody, dry-sweet, and extremely tenacious odor
LogP
6.790 (est)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H400Very toxic to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
E678100
Product name
Manool(80%)
Packaging
100mg
Price
$160
Updated
2021/12/16
Biosynth Carbosynth
Product number
FM65852
Product name
Manool
Packaging
100mg
Price
$200
Updated
2021/12/16
AK Scientific
Product number
9756AJ
Product name
Manool
Packaging
50mg
Price
$218
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0003252
Product name
MANOOL
Purity
95.00%
Packaging
100MG
Price
$329.7
Updated
2021/12/16
Biosynth Carbosynth
Product number
FM65852
Product name
Manool
Packaging
250mg
Price
$350
Updated
2021/12/16
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MANOOL Chemical Properties,Usage,Production

Uses

Maintains anti-proliferative activity against human malignant cell strains.

Definition

ChEBI: A labdane diterpenoid in which the labdane skeleton has double bonds at positions 8(17) and 14 and carries an R-hydroxy group at position 13.

Preparation

By extraction of cornrninuted wood of Dacrydium biforme, a tree indigenous to New Zealand, with alcohol or Acetone. The extract is neutralized with alkali, and the crude Manool may be recrystallized.

Cytotoxicity

IC50 (μg/mL): 49.3 (V79), 15.6 (B16F10),17.1 (MCF-7), 6.7 (HeLa), 28.5 (HepG2),9.6 (MO59 J), 6.7 (U343), 13.1 (U251)(de Oliveira et al. 2016)

MANOOL Preparation Products And Raw materials

Raw materials

Preparation Products

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MANOOL Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58
Hubei xin bonus chemical co. LTD
Tel
86-13657291602
Fax
027-59338440
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
22963
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29774
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58
Tel
4008-099-669
Email
23419001name@qq.com
Country
CHINA
ProdList
70071
Advantage
58

596-85-0, MANOOLRelated Search:


  • MANOOL
  • 4AR-TRANS-5-(1,5,5,8AS-TETRAMETHYL-2-METHYLENEDECAHYDRO-1-NAPHTHALENYL)-3-R-METHYL-1-PENTEN-3-OL
  • 1-Naphthalenepropanol, alpha-ethenyldecahydro-alpha,5,5,8a-tetramethyl-2-methylene-, [1S-[1alpha(S*),4abeta,8aalpha]]-
  • 5-(5,5,8a-Trimethyl-2-methylenedecahydro-1-naphthalenyl)-3-methyl-1-penten-3-ol
  • Labda-8(20),14-dien-13-ol, (13R)-
  • 4ARTRANS-5-(-TETRAME-2-METHYLENEDECAHYDR
  • 1-Naphthalenepropanol, .alpha.-ethenyldecahydro-.alpha.,5,5,8a-tetramethyl-2-methylene-, (.alpha.R,1S,4aS,8aS)-
  • 1-Naphthalenepropanol, .alpha.-ethenyldecahydro-.alpha.,5,5,8A-tetramethyl-2-methylene-, [1S-[1.alpha.(S*),4A.beta.,8A.alpha.]]-
  • Nsc165961
  • (αR,1S,4aS,8aS)-α-Ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-1-napthalenepropanol
  • (13R)-Labda-8(17),14-diene-13-ol
  • (1S,4aα,αR)-Decahydro-α-vinyl-α,5,5,8aβ-tetramethyl-2-methylene-1-naphthalene-1-propanol
  • [13R,(+)]-Labda-8(17),14-dien-13-ol
  • [13R,(+)]-Labda-8(17),14-diene-13-ol
  • 1-Naphthalenepropanol, α-ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-, (αR,1S,4aS,8aS)-
  • Manool (80%)
  • (αR,1S,4aS,8aS)-α-Ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-1-napthalenepropanol
  • 596-85-0
  • Organic Building Blocks
  • Asymmetric Synthesis
  • Chiral Building Blocks
  • Alcohols
  • Miscellaneous Natural Products