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MANOOL

Product Name
MANOOL
CAS No.
596-85-0
Chemical Name
MANOOL
Synonyms
MANOOL;Nsc165961;Manool (80%);(13R)-Labda-8(17),14-diene-13-ol;Labda-8(20),14-dien-13-ol, (13R)-;[13R,(+)]-Labda-8(17),14-dien-13-ol;[13R,(+)]-Labda-8(17),14-diene-13-ol;4ARTRANS-5-(-TETRAME-2-METHYLENEDECAHYDR;5-(5,5,8a-Trimethyl-2-methylenedecahydro-1-naphthalenyl)-3-methyl-1-penten-3-ol;(αR,1S,4aS,8aS)-α-Ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-1-napthalenepropanol
CBNumber
CB2334659
Molecular Formula
C20H34O
Formula Weight
290.48
MOL File
596-85-0.mol
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MANOOL Property

Melting point:
49-52 °C(lit.)
Boiling point:
150-153 °C(Press: 0.3 Torr)
Density 
0.93±0.1 g/cm3(Predicted)
Flash point:
>230 °F
storage temp. 
4°C, stored under nitroge
solubility 
Benzene (Slightly), Chloroform (Slightly), Methanol (Slightly)
form 
Low-Melting Solid
pka
14.47±0.29(Predicted)
color 
White to Off-White
Specific Gravity
0.97
Odor
Very delicate, woody, dry-sweet, and extremely tenacious odor
LogP
6.790 (est)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H400Very toxic to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
E678100
Product name
Manool(80%)
Packaging
100mg
Price
$160
Updated
2021/12/16
Biosynth Carbosynth
Product number
FM65852
Product name
Manool
Packaging
100mg
Price
$200
Updated
2021/12/16
AK Scientific
Product number
9756AJ
Product name
Manool
Packaging
50mg
Price
$218
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0003252
Product name
MANOOL
Purity
95.00%
Packaging
100MG
Price
$329.7
Updated
2021/12/16
Biosynth Carbosynth
Product number
FM65852
Product name
Manool
Packaging
250mg
Price
$350
Updated
2021/12/16
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MANOOL Chemical Properties,Usage,Production

Uses

Maintains anti-proliferative activity against human malignant cell strains.

Definition

ChEBI: A labdane diterpenoid in which the labdane skeleton has double bonds at positions 8(17) and 14 and carries an R-hydroxy group at position 13.

Preparation

By extraction of cornrninuted wood of Dacrydium biforme, a tree indigenous to New Zealand, with alcohol or Acetone. The extract is neutralized with alkali, and the crude Manool may be recrystallized.

Cytotoxicity

IC50 (μg/mL): 49.3 (V79), 15.6 (B16F10),17.1 (MCF-7), 6.7 (HeLa), 28.5 (HepG2),9.6 (MO59 J), 6.7 (U343), 13.1 (U251)(de Oliveira et al. 2016)

MANOOL Preparation Products And Raw materials

Raw materials

Preparation Products

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MANOOL Suppliers

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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+86-400-002-6226 +86-13028896684;
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sales@rrkchem.com
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Hubei xin bonus chemical co. LTD
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86-13657291602
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027-59338440
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CHINA
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
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QQ 3610331285
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sales@chemegen.com
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Energy Chemical
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021-58432009 400-005-6266
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021-58436166
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marketing@energy-chemical.com
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China
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44918
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 15801484223;
Email
psaitong@jm-bio.com
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China
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29774
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58
TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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China
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Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627
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customer_service@efebio.com
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4008-099-669
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GIHI CHEMICALS CO.,LIMITED
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+8618058761490
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Shaanxi Didu New Materials Co. Ltd
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Shanghai Yihui Biotechnology Co., Ltd.
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Shanghai Boyi Biotechnology Co., Ltd.
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Shanghai Benrui Biotechnology Co., Ltd.
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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Carbosynth China Ltd.
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Shenzhen Sailing Chemical.Co.,Ltd
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Guangzhou WeiBo Chemical Co., Ltd.
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weibochem@163.com
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596-85-0, MANOOLRelated Search:


  • MANOOL
  • 4AR-TRANS-5-(1,5,5,8AS-TETRAMETHYL-2-METHYLENEDECAHYDRO-1-NAPHTHALENYL)-3-R-METHYL-1-PENTEN-3-OL
  • 1-Naphthalenepropanol, alpha-ethenyldecahydro-alpha,5,5,8a-tetramethyl-2-methylene-, [1S-[1alpha(S*),4abeta,8aalpha]]-
  • 5-(5,5,8a-Trimethyl-2-methylenedecahydro-1-naphthalenyl)-3-methyl-1-penten-3-ol
  • Labda-8(20),14-dien-13-ol, (13R)-
  • 4ARTRANS-5-(-TETRAME-2-METHYLENEDECAHYDR
  • 1-Naphthalenepropanol, .alpha.-ethenyldecahydro-.alpha.,5,5,8a-tetramethyl-2-methylene-, (.alpha.R,1S,4aS,8aS)-
  • 1-Naphthalenepropanol, .alpha.-ethenyldecahydro-.alpha.,5,5,8A-tetramethyl-2-methylene-, [1S-[1.alpha.(S*),4A.beta.,8A.alpha.]]-
  • Nsc165961
  • (αR,1S,4aS,8aS)-α-Ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-1-napthalenepropanol
  • (13R)-Labda-8(17),14-diene-13-ol
  • (1S,4aα,αR)-Decahydro-α-vinyl-α,5,5,8aβ-tetramethyl-2-methylene-1-naphthalene-1-propanol
  • [13R,(+)]-Labda-8(17),14-dien-13-ol
  • [13R,(+)]-Labda-8(17),14-diene-13-ol
  • 1-Naphthalenepropanol, α-ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-, (αR,1S,4aS,8aS)-
  • Manool (80%)
  • (αR,1S,4aS,8aS)-α-Ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-1-napthalenepropanol
  • 596-85-0
  • Organic Building Blocks
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