ChemicalBook > CAS DataBase List > TD52
TD52
- Product Name
- TD52
- CAS No.
- 1798328-24-1
- Chemical Name
- TD52
- Synonyms
- TD52;TD52 >=98% (HPLC);N2,N3-Bis(3-ethynylphenyl)quinoxaline-2,3-diamine;2,3-Quinoxalinediamine, N2,N3-bis(3-ethynylphenyl)-;breast,triple-negative,TD52,inhibit,HCC-1937,orally,Erlotinib,TD 52,CIP2A,Protein kinase B,p-Akt,p-EGFR,Apoptosis,PKB,Elk1,PP2A,Inhibitor,TD-52,cancer,Phosphatase,TNBC,Akt
- CBNumber
- CB23364118
- Molecular Formula
- C24H16N4
- Formula Weight
- 360.41
- MOL File
- 1798328-24-1.mol
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TD52 Property
- Boiling point:
- 530.0±50.0 °C(Predicted)
- Density
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 5 mg/ml; DMSO: 5 mg/ml
- form
- A solid
- pka
- 2.45±0.59(Predicted)
- color
- White to yellow
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TD52 Chemical Properties,Usage,Production
Biological Activity
TD52, an erlotinib analog, is a putative inhibitor of CIP2A th at exhibits potent antitumor efficacy on HCC and TNBC cells. TD52 induces apoptosis through downregulation of CIP2A (Cancerous inhibitor of protein phosphatase 2A) in HCC, NSCLC and TNBC cells. Apparently TD52 indirectly downregulates CIP2A transcripts through interrupting the binding of Elk1 to CIP2A promoter. TD52 is a weak inhibitor of EGFR tyrosine kinase.
TD52 Preparation Products And Raw materials
Raw materials
Preparation Products
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TD52 Suppliers
- Tel
- +8613564774135
- zijue.cai@tsbiochem.com
- Country
- United States
- ProdList
- 19881
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- 58
- Tel
- support@targetmol.com
- Country
- United States
- ProdList
- 38631
- Advantage
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- Country
- United States
- ProdList
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