ChemicalBook > CAS DataBase List > Mitiglinide calcium dihydrate

Mitiglinide calcium dihydrate

Product Name: Mitiglinide calcium dihydrate
CAS No.: 207844-01-7
Chemical Name: Mitiglinide calcium dihydrate
Synonyms: Mitiglinide calcium;KAD-1229 Calcium Hydrate;Mitig;MitigL;inide caL;Miglitol Calcium;KAD-1229 calcium salt;Miglinide Calcium API;S-21403 calcium hydrate;Mitiglinide CalciuM dihydrate
CBNumber: CB2336628
Molecular Formula: C38H52CaN2O8
Formula Weight: 704.91
MOL File: 207844-01-7.mol

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Mitiglinide calcium dihydrate Property

Melting point:: 179-185°C
storage temp.: Inert atmosphere,Room Temperature
solubility: Methanol (Slightly)
form: Solid
color: White
InChIKey: QEVLNUAVAONTEW-HNIWBTCONA-L
SMILES: N1(C[C@]2([H])CCCC[C@]2([H])C1)C(=O)C[C@H](CC1=CC=CC=C1)C(=O)O[Ca]OC(=O)[C@@H](CC1=CC=CC=C1)CC(=O)N1C[C@@]2([H])CCCC[C@@]2([H])C1.O.O |&1:2,8,14,29,42,48,r|
CAS DataBase Reference: 207844-01-7(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: K090000
Product name: KAD-1229CalciumHydrate
Packaging: 500mg
Price: $230
Updated: 2021/12/16

Usbiological

Product number: 281061
Product name: KAD-1229 calcium hydrate
Packaging: 50mg
Price: $315
Updated: 2021/12/16

AK Scientific

Product number: O660
Product name: Mitiglinidecalciumsaltdihydrate
Packaging: 25mg
Price: $25
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB24752
Product name: (S)-2-Benzyl-4-oxo-4-(cis-perhydroisoindol-2-yl)butyric acid calcium salt hydrate
Packaging: 50mg
Price: $47
Updated: 2021/12/16

ChemScene

Product number: CS-4570
Product name: Mitiglinidecalciumhydrate
Packaging: 100mg
Price: $60
Updated: 2021/12/16

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Mitiglinide calcium dihydrate Chemical Properties,Usage,Production

Description

Mitiglinide calcium hydrate (KAD-1229) is an insulinotropic agent. Mitiglinide calcium hydrate is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel). Mitiglinide is a drug for the treatment of type 2 diabetes. It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels.

Chemical Properties

White Solid

Uses

KAD-1229 Calcium Hydrate (Mitiglinide calcium dihydrate) could binds to sulfonylurea receptors and inhibits the activity of ATP-sensitive K+ channel in MIN 6 cells. Antidiabetic.

Mechanism of action

Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) (K(ATP)) channels in pancreatic beta-cells, and its early insulin release and short duration of action would be effective in improving postprandial hyperglycemia.

in vivo

Mitiglinide Calcium hydrate (1-3 mg/kg; p.o.) suppresses the increase in plasma glucose levels seen after a meal load and the area under the curve for plasma glucose levels (AUCglucose) up to 5 h after the meal load^[2].

Animal Model:	Pregnant Wistar rats (12 weeks)^[2]
Dosage:	0.3 mg/kg, 1 mg/kg, 3 mg/kg
Administration:	Oral administration
Result:	Dose-dependently suppressed AUC_glucose levels.

Mitiglinide calcium dihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Mitiglinide calcium dihydrate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Mitiglinide calcium dihydrate 207844-01-7
Price: US $0.00/G
Min. Order: 25G
Purity: 98%min
Supply Ability: 30kg/month
Release date: 2023-02-03

Hebei Chuanghai Biotechnology Co., Ltd

Product: Mitiglinide calcium dihydrate 207844-01-7
Price: US $10.00/KG
Min. Order: 100KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-12-03

Hangzhou ICH Biofarm Co., Ltd

Product: Mitiglinide calcium 207844-01-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.0% min
Supply Ability: 1000kgs/month
Release date: 2023-06-12

207844-01-7, Mitiglinide calcium dihydrateRelated Search:

Diethylstilbestrol Calcium oxide Benzyl alcohol Benzyl bromide Benzyl benzoate Calcium formate Calcium chloride Calcium Propionate [2(S)-cis]-Octahydro-gamma-oxo-alpha-(phenylmethyl)-2H-isoindole-2-butanoic acid calcium sulfate Repaglinide Calcium carbonate cis-Octahydroisoindole CALCIUM ISOBUTYRATE Mivobulin MITIGLINIDE CALCIUM HYDRATE,Mitiglinide calcium,Mitiglinide calcium anhydrous CALCIUM Repaglinide Tablet

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Mitiglinide CalciuM dihydrate

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KAD-1229 calcium salt

2H-ISOINDOLE-2-BUTANOIC ACID, OCTAHYDRO-GAMMA-OXO-ALPHA-(PHENYLMETHYL)-, CALCIUM SALT, DIHYDRATE, (AS,3AR,7AS)-

calcium 4-(1,3,3a,4,5,6,7,7a-octahydroisoindol-2-yl)-4-oxo-2-(phenylmethyl)butanoate dihydrate

KAD-1229 CALCIUM HYDRATE;S-21403 CALCIUM HYDRATE

S-21403 calcium hydrate

inide caL

Mitig

MitigL

Mitiglinide calcium dihydrate USP/EP/BP

Mitiglinide calcium salt 2-hydrate

Mitiglinide calcium hydrateQ: What is Mitiglinide calcium hydrate Q: What is the CAS Number of Mitiglinide calcium hydrate Q: What is the storage condition of Mitiglinide calcium hydrate Q: What are the applications of Mitiglinide calcium hydrate

Miglinide Calcium API

Calcium (S)-2-benzyl-4-((3aR,7aS)-octahydro-2H-isoindol-2-yl)-4-oxobutanoate dihydrate

Mitiglinide (calcium salt, hydrate)

Mitiglinide calcium hydrate, 10 mM in DMSO

Miglitol Calcium

Mitiglinide calcium hydrate (KAD-1229 calcium hydrate

Abmole M4968-50mg Mitiglinide calcium hydrate 207844-01-7

207844-01-7

07844-01-7

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