ChemicalBook > CAS DataBase List > MELK-T1(JNJ-47117096)
MELK-T1(JNJ-47117096)
- Product Name
- MELK-T1(JNJ-47117096)
- CAS No.
- 1610586-62-3
- Chemical Name
- MELK-T1(JNJ-47117096)
- Synonyms
- MELK-T1;JNJ-47117096;MELK-T1(JNJ-47117096);2-methoxy-4-(1H-pyrazol-4-yl)-N-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)benzamide;Benzamide, 2-methoxy-4-(1H-pyrazol-4-yl)-N-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)-
- CBNumber
- CB23370416
- Molecular Formula
- C21H22N4O2
- Formula Weight
- 362.42
- MOL File
- 1610586-62-3.mol
More
Less
MELK-T1(JNJ-47117096) Property
- Boiling point:
- 558.8±50.0 °C(Predicted)
- Density
- 1.250±0.06 g/cm3(Predicted)
- pka
- 13.13±0.50(Predicted)
More
Less
N-Bromosuccinimide Price
DC Chemicals
- Product number
- DC11465
- Product name
- MELK-T1
- Purity
- >98%
- Packaging
- 100mg
- Price
- $650
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC11465
- Product name
- MELK-T1
- Purity
- >98%
- Packaging
- 250mg
- Price
- $1200
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC11465
- Product name
- MELK-T1
- Purity
- >98%
- Packaging
- 1g
- Price
- $2200
- Updated
- 2021/12/16
More
Less
MELK-T1(JNJ-47117096) Chemical Properties,Usage,Production
Uses
JNJ-47117096 is potent and selective MELK inhibitor, with an IC50 of 23 nM, also effectively inhibits Flt3, with an IC50 of 18 nM[1].
References
[1] Johnson CN, et al. Fragment-based discovery of type I inhibitors of maternal embryonic leucine zipper kinase. ACS Med Chem Lett. 2014 May 23;6(1):25-30. DOI:10.1021/ml5001245
[2] Beke L, et al. MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells. Biosci Rep. 2015 Oct 2;35(6). pii: e00267. DOI:10.1042/BSR20150194
MELK-T1(JNJ-47117096) Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
MELK-T1(JNJ-47117096) Suppliers
- Tel
- Fax
- 86-21-57758967
- sales@boylechem.com
- Country
- China
- ProdList
- 2922
- Advantage
- 55
- Tel
- 021-61350663 13052117465
- Fax
- 021-61350662
- sales@zehanbiopharma.com
- Country
- China
- ProdList
- 984
- Advantage
- 55
- Tel
- 177-54423994 17754423994
- Fax
- QQ:2853530913
- 2853530910@QQ.com
- Country
- China
- ProdList
- 8000
- Advantage
- 62
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 021-58111628 15800915896
- Fax
- QQ 3285589261
- sales@twochem.com
- Country
- China
- ProdList
- 1788
- Advantage
- 58
- Tel
- 15006117673
- Fax
- 2973592490@.com
- 2973592490@qq.com
- Country
- China
- ProdList
- 299
- Advantage
- 58
- Tel
- 18081075745
- chemflowtech@sina.com
- Country
- China
- ProdList
- 1886
- Advantage
- 58
- Tel
- 86-571-88216897,88216896 13588875226
- Fax
- 86-571-88216895
- sales@hzclap.com
- Country
- CHINA
- ProdList
- 6312
- Advantage
- 58
- Tel
- 63313187 15358055255
- Fax
- QQ:63313187
- 63313187@qq.com
- Country
- China
- ProdList
- 1984
- Advantage
- 58
- Tel
- 15727060112
- yutianchun2007@126.com
- Country
- China
- ProdList
- 9814
- Advantage
- 58
1610586-62-3, MELK-T1(JNJ-47117096)Related Search:
JNJ7777120
JNJ-64619178
4-[3-(Trifluoromethyl)-2-pyridinyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazinecarboxamide
jnj39758979
JNJ-632