DBCO-PEG4-NH-Boc

Product Name: DBCO-PEG4-NH-Boc
CAS No.: 1255942-12-1
Chemical Name: DBCO-PEG4-NH-Boc
Synonyms: DBCO-PEG4-NH-Boc;DBCO-NHCO-PEG4-NH-Boc;DBCO-NHCO-PEG4-t-Boc Amine;5,8,11,14-Tetraoxa-2,18-diazaheneicosanoic acid, 21-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,21-dioxo-, 1,1-dimethylethyl ester
CBNumber: CB23373604
Molecular Formula: C34H45N3O8
Formula Weight: 623.74
MOL File: 1255942-12-1.mol

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DBCO-PEG4-NH-Boc Property

Boiling point:: 840.5±65.0 °C(Predicted)
Density: 1.21±0.1 g/cm3(Predicted)
solubility: Soluble in DMSO, DCM, DMF
form: Viscous Liquid
pka: 12.23±0.46(Predicted)
color: Colorless to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23623
Product name: DBCO-NHCO-PEG4-NH-Boc
Purity: 98%
Packaging: 50mg
Price: $280
Updated: 2021/12/16

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DBCO-PEG4-NH-Boc Chemical Properties,Usage,Production

Description

DBCO-NHCO-PEG4-NH-Boc is a click chemistry reagent. it can undergo copper-free Click Chemistry reactions with azides. The Boc protecting group can be removed under acidic conditions.

Biological Activity

DBCO-NHCO-PEG4-NH-Boc is a PROTAC linker that belongs to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).

in vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Cleavable

PEGs

Alkyl/ether

DBCO-PEG4-NH-Boc Preparation Products And Raw materials

Raw materials

Preparation Products

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DBCO-PEG4-NH-Boc Suppliers

China 24 United States 5 Global 29

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View Lastest Price from DBCO-PEG4-NH-Boc manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: DBCO-NHCO-PEG4-NHBoc 1255942-12-1
Price: US $0.00/mg
Min. Order: 50mg
Purity: >95.00%
Supply Ability: 250mg
Release date: 2024-03-20

1255942-12-1, DBCO-PEG4-NH-BocRelated Search:

DBCO-PEG4-NH-Boc

DBCO-NHCO-PEG4-NH-Boc

DBCO-NHCO-PEG4-t-Boc Amine

5,8,11,14-Tetraoxa-2,18-diazaheneicosanoic acid, 21-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,21-dioxo-, 1,1-dimethylethyl ester

1255942-12-1

C34H45N3O8