N-Mal-N-bis(PEG2-t-butyl ester)
- Product Name
- N-Mal-N-bis(PEG2-t-butyl ester)
- CAS No.
- 2100306-51-0
- Chemical Name
- N-Mal-N-bis(PEG2-t-butyl ester)
- Synonyms
- N-Mal-N-bis(PEG2-C2-Boc);N-Mal-N-bis(PEG2-t-butyl ester);4,7,13,16-Tetraoxa-10-azanonadecanedioic acid, 10-[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-, 1,19-bis(1,1-dimethylethyl) ester
- CBNumber
- CB23373745
- Molecular Formula
- C29H48N2O11
- Formula Weight
- 600.7
- MOL File
- 2100306-51-0.mol
N-Mal-N-bis(PEG2-t-butyl ester) Property
- Boiling point:
- 671.9±55.0 °C(Predicted)
- Density
- 1.154±0.06 g/cm3(Predicted)
- solubility
- Soluble in DMSO, DCM, DMF
- pka
- -0.93±0.70(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-23730
- Product name
- N-Mal-N-bis(PEG2-t-butylester)
- Purity
- 98%
- Packaging
- 100mg
- Price
- $350
- Updated
- 2021/12/16
N-Mal-N-bis(PEG2-t-butyl ester) Chemical Properties,Usage,Production
Description
N-Mal-N-bis(PEG2-t-butyl ester) is a branched maleimide ester. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The t-butyl pester can be hydrolyzed under mild acidic conditions.
Uses
N-Mal-N-bis(PEG2-C2-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-Mal-N-bis(PEG2-t-butyl ester) Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N-Mal-N-bis(PEG2-t-butyl ester) manufacturers
- Product
- N-Mal-N-bis(PEG2-t-butyl ester) 2100306-51-0
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >95.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-28