5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE

Product Name
5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
CAS No.
144625-67-2
Chemical Name
5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
Synonyms
GR 125487;GR 125487 SULFAMATE;GR 125487 SULFAMATE SALT;(1-(2-(Methylsulfonamido)ethyl)piperidin-4-yl)-methyl 5-fluoro-2-methoxy-1H-indole-3-carboxyla;(1-(2-(Methylsulfonamido)ethyl)piperidin-4-yl)-methyl 5-fluoro-2-methoxy-1H-indole-3-carboxylate;5-Fluoro-2-methoxy-[1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]-1H-indole-3-methylcarboxylatesulfamate;5-fluoro-2-Methoxy-1H-Indole-3-carboxylic acid-[1-[2-[(Methylsulfonyl)aMino]ethyl]-4-piperidinyl]Methyl ester;5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE;1H-Indole-3-carboxylic acid, 5-fluoro-2-methoxy-, [1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]methyl ester;[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]METHYL 5-FLUORO-2-METHOXY-1H-INDOLE-3-CARBOXYLATE SULFAMATE SALT
CBNumber
CB2346616
Molecular Formula
C19H26FN3O5S
Formula Weight
427.49
MOL File
144625-67-2.mol
More
Less

5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE Property

Melting point:
118-120℃
Boiling point:
613.4±65.0 °C(Predicted)
Density 
1.313±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
H2O: ~14 mg/mL at 60 °C, soluble
form 
solid
pka
11.22±0.40(Predicted)
color 
off-white
More
Less

Safety

WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Tocris
Product number
1658
Product name
GR125487sulfamate
Purity
≥97%(HPLC)
Packaging
10
Price
$223
Updated
2021/12/16
Tocris
Product number
1658
Product name
GR125487sulfamate
Purity
≥97%(HPLC)
Packaging
50
Price
$872
Updated
2021/12/16
Usbiological
Product number
451421
Product name
GR 125487 Sulfamate
Packaging
1mg
Price
$389
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008782
Product name
5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
Purity
95.00%
Packaging
10MG
Price
$714.32
Updated
2021/12/16
AK Scientific
Product number
7131AA
Product name
(1-(2-(Methylsulfonamido)ethyl)piperidin-4-yl)methyl5-fluoro-2-methoxy-1H-indole-3-carboxylate
Packaging
250mg
Price
$1051
Updated
2021/12/16
More
Less

5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE Chemical Properties,Usage,Production

Uses

GR 125487 Sulfamate is potent, selective 5-HT4 antagonist; active in vivo.

Biological Activity

Potent and selective 5-HT 4 receptor antagonist (K i = 0.19 nM for porcine 5-HT 4 ). Centrally active following systemic administration in vivo .

5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE Suppliers

China 10 Germany 1 Switzerland 1 United Kingdom 1 United States 6 Global 19
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16687
Advantage
50
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Shanghai Universal Biotech Co.,Ltd
Tel
18768175414
Email
gaojun@univ-bio.com
Country
China
ProdList
24998
Advantage
58

144625-67-2, 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATERelated Search:

5-FLUOROINDOLE-3-CARBOXYLIC ACID 5-FLUORO-1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE [1-(2-aminoethyl)-4-piperidinyl]methanol 5-FLUOROINDOLE-3-CARBOXALDEHYDE

  • [1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]METHYL 5-FLUORO-2-METHOXY-1H-INDOLE-3-CARBOXYLATE SULFAMATE SALT
  • 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
  • GR 125487 SULFAMATE
  • GR 125487 SULFAMATE SALT
  • 5-Fluoro-2-methoxy-[1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]-1H-indole-3-methylcarboxylatesulfamate
  • 5-fluoro-2-Methoxy-1H-Indole-3-carboxylic acid-[1-[2-[(Methylsulfonyl)aMino]ethyl]-4-piperidinyl]Methyl ester
  • GR 125487
  • (1-(2-(Methylsulfonamido)ethyl)piperidin-4-yl)-methyl 5-fluoro-2-methoxy-1H-indole-3-carboxylate
  • (1-(2-(Methylsulfonamido)ethyl)piperidin-4-yl)-methyl 5-fluoro-2-methoxy-1H-indole-3-carboxyla
  • 1H-Indole-3-carboxylic acid, 5-fluoro-2-methoxy-, [1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]methyl ester
  • 144625-67-2
  • C19H26FN3O5SSO3NH2
  • C19H26FN3O5SH2NSO3H
  • C19H26FN3O5S