3,4-Dimethoxyphenol

Product Name: 3,4-Dimethoxyphenol
CAS No.: 2033-89-8
Chemical Name: 3,4-Dimethoxyphenol
Synonyms: NSC 140927;3,4-Dimethoxyphel;4-HYDROXYVERATROLE;3,4-DIMETHOXYPHENOL;3,4-dimethoxy-pheno;3,4-diMethoxyphenoxyl;Phenol, 3,4-dimethoxy-;3,4-Dimethoxyphenol,97%;3,4-Dimethoxyphenol >3,4-Bis(Methyloxy)phenol
CBNumber: CB2354549
Molecular Formula: C8H10O3
Formula Weight: 154.16
MOL File: 2033-89-8.mol

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3,4-Dimethoxyphenol Property

Melting point:: 79-82 °C (lit.)
Boiling point:: 167°C/14mm
Density: 1.1690 (rough estimate)
refractive index: 1.4740 (estimate)
Flash point:: 167°C/14mm
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 10.08±0.18(Predicted)
form: Fine Crystalline Powder
color: Off-white to light beige
Water Solubility: Soluble in water.
Sensitive: Light Sensitive
BRN: 1366650
LogP: 1.157 (est)
CAS DataBase Reference: 2033-89-8(CAS DataBase Reference)
NIST Chemistry Reference: Phenol, 3,4-dimethoxy-(2033-89-8)
EPA Substance Registry System: 3,4-Dimethoxyphenol (2033-89-8)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
F: 10
TSCA: Yes
HS Code: 29095000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 194468
Product name: 3,4-Dimethoxyphenol
Purity: 97%
Packaging: 10g
Price: $176
Updated: 2024/03/01

TCI Chemical

Product number: D3221
Product name: 3,4-Dimethoxyphenol
Purity: >97.0%(GC)
Packaging: 5g
Price: $97
Updated: 2024/03/01

TCI Chemical

Product number: D3221
Product name: 3,4-Dimethoxyphenol
Purity: >97.0%(GC)
Packaging: 25g
Price: $330
Updated: 2024/03/01

Alfa Aesar

Product number: A11344
Product name: 3,4-Dimethoxyphenol, 98%
Packaging: 5g
Price: $96.4
Updated: 2024/03/01

Alfa Aesar

Product number: A11344
Product name: 3,4-Dimethoxyphenol, 98%
Packaging: 25g
Price: $357.65
Updated: 2024/03/01

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3,4-Dimethoxyphenol Chemical Properties,Usage,Production

Chemical Properties

Red Crystal Powder

Uses

3,4-Dimethoxyphenol is used in the preparation of 5,6-dimethoxy benzofuranone derivatives and multi-target anti Alzheimer compounds. It is also used in the preparation of 3,4-dimethoxyphenyl-beta-D-glucopyranoside and 4-(but-2-enyloxy)-1,2-dimethoxybenzene. Further, it serves as a precursor for 4H-chromenes synthesis.

Uses

A substituted alkynyl phenoxy compound as new synergists in pesticidal compositions.

Synthesis

3,4-Dimethoxyphenol is synthesised using Veratraldehyde as a raw material by chemical reaction. The specific synthesis steps are as follows:
Method (i): To a solution of vertraldehyde (2.11)(5 g,0.03 mole)in glacial acetic acid (30 ml)is added dropwise to a solution of peracetic acid5(15 ml) during 30 min.The temperature of the reaction mixture rises,it is kept at 40-45 by cooling.The reaction mixture is left for 10 hr and then concentrated to about 15 ml in vacuo.The residue is extracted with ether (2 x 20 ml).The ether layer is distilled.The formate ester of 3,4- dimethoxyphenol thus obtained is hydrolysed by refluxing with potassium hydroxide (10 g)in aqueous alcohol (1:4,100 ml)for 1 hr.The reaction mixture is concentrated in vacuo almost to dryness.It is dissolved in water (20 ml),the solution rendered acidic with dilute sulphuric acid and extracted with ether.The ether extract is dried (sodium sulphate)and distilled.The oily residue thus obtained is subjected to column chromatography over silica gel(2 x 30 cm).Elution with benzene gave 3,4-dimethoxyphenol as yellow solid.Yield 3g(65.2%).It is crystallised from benzene as yellow crystalline needles.M.p.78-80(lit.m.p.78-80).

Method (ii): A mixture of veratraldehyde (2.11)(1.66 g,0.01 mole),hydrogen peroxide (30%,2.6 ml,0.023 mole),p-toluenesulphonic acid (6.88 g, 0.036 mole)and methanol (5 ml)is stirred at room temperature.When the reaction is complete (as monitored by TLC)the reaction mixture is diluted with water (50 ml)and extracted with dichloromethane (5 x 50 ml).The extract is dried (anhydrous sodium sulphate)and purified by column chromatography over silica gel(2 x 30 cm).Elution with benzene gave 3,4. dimethoxyphenol as an yellow solid.Yield 1.16 g (75.3%).M.p.78-80.

3,4-Dimethoxyphenol Preparation Products And Raw materials

Raw materials

Preparation Products

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3,4-Dimethoxyphenol Suppliers

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View Lastest Price from 3,4-Dimethoxyphenol manufacturers

Hubei Lidu New Material Technology Co., Ltd

Product: 3,4-DIMETHOXYPHENOL 2033-89-8
Price: US $0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 20tons
Release date: 2024-09-19

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 3,4-Dimethoxyphenol 2033-89-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-01-10

Hebei Weibang Biotechnology Co., Ltd

Product: 3,4-Dimethoxyphenol 2033-89-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-11-26

2033-89-8, 3,4-DimethoxyphenolRelated Search:

3,4-Dimethoxybenzoic acid p-(2-Methoxyethyl) phenol Dimethyldimethoxysilane Guaiacol 4-Methoxyphenol (3,4-Dimethoxyphenyl)acetic acid Xylenol orange tetrasodium salt 2-Ethoxyphenol 1,3-Dimethoxybenzene 3,5-Dimethoxyphenol 2,6-Dimethoxyphenol 3,4,5-Trimethoxyphenol 2,4,5-Trimethoxybenzoic acid 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN SCOPARONE 1,2,4-Trimethoxybenzene PRECOCENE II trans-2,4,5-Trimethoxycinnamic acid

4-HYDROXYVERATROLE

Phenol, 3,4-dimethoxy-

3,4-Dimethoxyphenol,97%

3,4-Bis(Methyloxy)phenol

3,4-Dimethoxyphel

3,4-diMethoxyphenoxyl

3,4-dimethoxy-pheno

3,4-DIMETHOXYPHENOL

NSC 140927

5‐Hydroxycatechol dimethyl ether

3,4-Dimethoxyphenol &gt

3,4-Dimethoxyphenol,>98%

3,4-Dimethoxyphenol, ≥ 97.0%

3,4-Dimethoxyphenol, 10 mM in DMSO

2033-89-8

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