3,5-Dimethoxyphenol

Product Name: 3,5-Dimethoxyphenol
CAS No.: 500-99-2
Chemical Name: 3,5-Dimethoxyphenol
Synonyms: Phenol, 3,5-dimethoxy-;NSC 70955;Taxicatigenin;3,5-DIMETHOXYPHENOL;3,5-Dimethoxyphenol>3,5-DiMethoxyphenol 99%;3,5-Dimethoxyphenol,97%;DIMETHOXYPHENOL, 3,5-(P);Phloroglucinol Impurity 24;Phloroglucin dimethyl ether
CBNumber: CB2268778
Molecular Formula: C8H10O3
Formula Weight: 154.16
MOL File: 500-99-2.mol

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3,5-Dimethoxyphenol Property

Melting point:: 40-43 °C (lit.)
Boiling point:: 172-175 °C/17 mmHg (lit.)
Density: 1.1690 (rough estimate)
refractive index: 1.4745 (estimate)
Flash point:: 173 °F
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka: pK1:9.345 (25°C)
form: Liquid
color: Clear colorless to orange-red to pale pink-brownish
Water Solubility: Soluble in methanol, ethanol, benzene, water (slightly), and chloroform.
Sensitive: Air & Light Sensitive
BRN: 1239156
InChI: 1S/C8H10O3/c1-10-7-3-6(9)4-8(5-7)11-2/h3-5,9H,1-2H3
InChIKey: XQDNFAMOIPNVES-UHFFFAOYSA-N
SMILES: COc1cc(O)cc(OC)c1
LogP: 1.640
CAS DataBase Reference: 500-99-2(CAS DataBase Reference)
NIST Chemistry Reference: Phenol, 3,5-dimethoxy-(500-99-2)
EPA Substance Registry System: Phenol, 3,5-dimethoxy- (500-99-2)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
F: 10
Hazard Note: Irritant
HS Code: 29095090
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 132632
Product name: 3,5-Dimethoxyphenol
Purity: 99%
Packaging: 10g
Price: $109
Updated: 2025/07/31

Sigma-Aldrich

Product number: 132632
Product name: 3,5-Dimethoxyphenol
Purity: 99%
Packaging: 50g
Price: $283
Updated: 2025/07/31

TCI Chemical

Product number: P0320
Product name: 3,5-Dimethoxyphenol
Purity: >98.0%(GC)
Packaging: 25g
Price: $149
Updated: 2025/07/31

TCI Chemical

Product number: P0320
Product name: 3,5-Dimethoxyphenol
Purity: >98.0%(GC)
Packaging: 100g
Price: $447
Updated: 2025/07/31

TRC

Product number: D461015
Product name: 3,5-Dimethoxyphenol
Packaging: 100g
Price: $470
Updated: 2021/12/16

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3,5-Dimethoxyphenol Chemical Properties,Usage,Production

Chemical Properties

slightly pink to yellow crystalline powder

Uses

3,5-dimethoxyphenol is a marker for poisoning from Taxus baccata.

Uses

3,5-Dimethoxyphenol is a phenol derivative as antinitrosating agent.

Definition

ChEBI: 3,5-Dimethoxyphenol is a member of methoxybenzenes and a member of phenols.

Synthesis

Ethanethiol (1.25g, 1.5 ml, 0.02 mole) dissolved in N, N- dimethyl-formamide (20 ml) is added to a suspension of sodium hydride (1 g of 50%oil dispersion) in dry DMF (10 ml) under an atmosphere of nitrogen. The mixture is stirred for 5 min under anhydrous conditions. A solution of phloroglucinol trimethyl ether (1.14) (1 g,0.006 moles) in dry DMF (10 ml)is added, and the mixture is refluxed for 3 hr. The reaction mixture is cooled and acidified with hydrochloric acid (10%). It is extracted with ether(3 x 50 ml). The ether extract is washed with water and extracted with sodium hydroxide solution (5%). The clear alkaline extract is acidified with hydrochloric acid. The mixture is extracted with ether. The ether extract is washed with water, ried (anhydrous sodium sulphate), and drilled. 3,5-Dimethoxyphenol is obtained as an oil. Yield 0.9 g (98.1%).B.p.198-199°/30 mm.

Purification Methods

Purify the phenol by distillation followed by sublimation in a vacuum. [Beilstein 6 IV 7362.]

3,5-Dimethoxyphenol Preparation Products And Raw materials

Raw materials

Preparation Products

4-Hydroxy-2,6-dimethoxybenzaldehyde

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3,5-Dimethoxyphenol Suppliers

Americas 1 Australia 1 Belgium 2 Canada 2 China 201 Europe 3 France 1 Germany 4 India 14 Japan 4 Slovakia 1 Spain 1 Switzerland 3 Ukraine 1 United Kingdom 18 United States 55 USA 1 Global 313

Hunan Caiya Biological Technology Co., Ltd

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J & K SCIENTIFIC LTD.

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Alfa Aesar

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Energy Chemical

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Wuhan Chemwish Technology Co., Ltd

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Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
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ProdList: 18207
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View Lastest Price from 3,5-Dimethoxyphenol manufacturers

Shanghai Wish Pharma Co., Ltd

Product: 3,5-Dimethoxyphenol 500-99-2
Price: US $0.00-0.00/kg
Min. Order: 0.5kg
Purity: Minimum 95%
Supply Ability: 300kg
Release date: 2025-11-06

Honest Joy Holdings Limited

Product: 3,5-Dimethoxyphenol 500-99-2
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.0%
Supply Ability: 100 tons
Release date: 2022-02-18

Career Henan Chemical Co

Product: 3,5-Dimethoxyphenol 500-99-2
Price: US $8.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10MT
Release date: 2018-12-21

500-99-2, 3,5-DimethoxyphenolRelated Search:

2-Ethoxyphenol Dimethyl sulfate Metformin Diphenyldimethoxysilane 1,1-Dimethoxyethane Phloroglucinol Dimethyl carbonate Dimethyl sulfoxide Dimethyl sulfide 3-Methoxyphenol Dimethyldimethoxysilane N,N-Dimethylformamide Guaiacol ETHANE Dimethyl fumarate Dacthal Dimethyl ether Dimethyl sebacate

PHLOROGLUCINOL DIMETHYL ETHER

3,5-DIMETHOXYPHENOL

1-Hydroxy-3,5-dimethoxybenzene

Taxicatigenin

3,5-Dimethoxy Phenol, 98%min

3,5-DIMETHYOXY PHENYL HYDROXIDE

Phenol, 3,5-dimethoxy-

Phloroglucinol Impurity 24

DIMETHOXYPHENOL, 3,5-(P)

3,5-DiMethoxyphenol 99%

Phloroglucin dimethyl ether

3,5-Dimethoxyphenol,97%

3,5-Dimethoxyphenol≥ 98% (GC)

3,5-Dimethoxyphenol,Phloroglucinol dimethyl ether

NSC 70955

3,5-Dimethoxyphenol&gt

3,5-Dimethoxyphenol in methanol

500-99-2

CH3O2C6H3OH

Building Blocks

Organic Building Blocks

Oxygen Compounds

Phenols

Aromatic Ethers

Building Blocks

C6 to C8

Chemical Synthesis

Organic Building Blocks

Oxygen Compounds

Phenols