ChemicalBook > CAS DataBase List > Nipecotic acid

Nipecotic acid

Product Name
Nipecotic acid
CAS No.
498-95-3
Chemical Name
Nipecotic acid
Synonyms
PIPERIDINE-3-CARBOXYLIC ACID;3-PIPERIDINECARBOXYLIC ACID;H-NIP-OH;DL-Nip-OH;H-D-NIPC-OH;H-DL-Nip-OH;H-DL-NIPC-OH;H-DL-PIC(3)-OH;NIPECOTIC ACID;D-NIPECOTIC ACID
CBNumber
CB2357287
Molecular Formula
C6H11NO2
Formula Weight
129.16
MOL File
498-95-3.mol
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Nipecotic acid Property

Melting point:
261 °C (dec.) (lit.)
Boiling point:
239.22°C (rough estimate)
Density 
1.1426 (rough estimate)
refractive index 
1.4587 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
water: soluble50mg/mL, clear, colorless to faintly yellow
form 
Solid
pka
pK1:3.35(+1);pK2:10.64(0) (25°C)
color 
White
Water Solubility 
Soluble in water
Merck 
14,6560
BRN 
81096
CAS DataBase Reference
498-95-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
TM6125380
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
211672
Product name
Nipecotic acid
Purity
98%
Packaging
1g
Price
$35.5
Updated
2023/01/07
Sigma-Aldrich
Product number
211672
Product name
Nipecotic acid
Purity
98%
Packaging
5g
Price
$38.9
Updated
2023/01/07
TCI Chemical
Product number
N0420
Product name
3-Piperidinecarboxylic Acid
Purity
>98.0%(T)
Packaging
25g
Price
$63
Updated
2024/03/01
TCI Chemical
Product number
N0420
Product name
3-Piperidinecarboxylic Acid
Purity
>98.0%(T)
Packaging
500g
Price
$561
Updated
2024/03/01
Alfa Aesar
Product number
B24723
Product name
Nipecotic acid, 98%
Packaging
1g
Price
$30.65
Updated
2024/03/01
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Nipecotic acid Chemical Properties,Usage,Production

Chemical Properties

off-white to pale yellow-beige powder

Uses

(+/-)-Nipecotic Acid (cas# 498-95-3) is a compound useful in organic synthesis.

Definition

ChEBI: A piperidinemonocarboxylic acid that is piperidine in which one of the hydrogens at position 3 is substituted by a carboxylic acid group.

Synthesis Reference(s)

The Journal of Organic Chemistry, 28, p. 602, 1963 DOI: 10.1021/jo01037a531

General Description

R(?)-Nipecotic acid is a potential inhibitor of uptake of γ-aminobutyric acid (GABA) in rat brain slices. Lipophilic derivatives of nipecotic acid are used as drugs for the treatment of epilepsy.

Nipecotic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Nipecotic acid Suppliers

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View Lastest Price from Nipecotic acid manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
Nipecotic acid 498-95-3
Price
US $50.00/kg
Min. Order
1kg
Purity
99.10%
Supply Ability
50000kg
Release date
2024-04-24
Hebei Yanxi Chemical Co., Ltd.
Product
nipecotic acid 498-95-3
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
1000kg
Release date
2023-09-08
Hebei Kingfiner Technology Development Co.Ltd
Product
Piperidine-3-carboxylic acid 498-95-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000kg
Release date
2023-12-06

498-95-3, Nipecotic acidRelated Search:

Ethyl 2-(Chlorosulfonyl)acetate Haloperidol 2,2,6,6-Tetramethyl-4-piperidinol DROPERIDOL Folic acid Citric acid Hyaluronic acid Triacetonediamine Ascoric Acid Diphenoxylate NIPECOTIC ACID ETHYL ESTER Ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride N-Methyl-3-carbomethoxy-4-piperidone hydrochloride 2,5-DIBROMOPIPERIDINE 3-CARBETHOXY-2-PIPERIDONE 4-OXO-PIPERIDINE-3-CARBOXYLIC ACID ETHYL ESTER BENZOYLECGONINE 1-BENZYL-3-METHOXYCARBONYL-4-PIPERIDONE

  • L-NIPECOTIC ACID
  • (3R)-(-)-PIPERIDIN-3-YLCARBOXYLIC ACID
  • (+/-)-3-PIPERIDINE CARBOXYLIC ACID
  • 3-PIPERIDINECARBOXYLIC ACID
  • DL-NIPECOTIC ACID
  • DL-3-PIPERIDINECARBOXYLIC ACID
  • (-)-D-NIPECOTIC ACID
  • D(-)-NIPECOTIC ACID
  • D-NIPECOTIC ACID
  • D-3-PIPERIDINECARBOXYLIC ACID
  • H-NIP-OH
  • LABOTEST-BB LT00233199
  • H-D-NIPC-OH
  • H-DL-NIPC-OH
  • H-DL-PIC(3)-OH
  • (+/-)-PIPERIDINE-3-CARBOXYLIC ACID
  • PIPERIDINE-3-CARBOXYLIC ACID
  • PIPERIDIN-3-CARBOXYLIC ACID
  • (R)-(-)-3-PIPERIDINECARBOXYLIC ACID
  • (+/-)-NIPECOTIC ACID
  • NIPECOTIC ACID
  • (R,S)-NIPECOTIC ACID
  • RARECHEM AK PQ 0322
  • RARECHEM AK HD C011
  • H-DL-Nip-OH
  • H-DL-Nip-OH~(+/-)-Piperidine-3-carboxylic acid
  • 3-PIPERIDINECARBOXYLIC ACID (NIPECOTIC ACID)
  • Nipecoticacid,98%
  • (+/-)-Piperidine-3-carboxylicacid(DL-Nipecoticacid)
  • (n)-piperidine-3-carboxylic acid
  • Piperidine-3-carboxylic acid 98%
  • NIPECOTIC ACID , PIPERIDINE-3-CARBOXYLIC ACID
  • Piperidine-3-carboxylic acid (Nipecotic Acid)
  • DL-Nipecotic acid, 98+%
  • rac-(3R*)-Piperidine-3-carboxylic acid
  • 3-nipecotic acid
  • H-DL-Nip-OH Nipecotic acid
  • 3-Piperidinecarboxylic acid ,98%
  • 3-carboxylic acid piperidine
  • 3-PiperidinecarboxyL
  • Nipecotic acid, 98% 25GR
  • 3-Carboxypiperidine
  • Hexahydronicotinic Acid
  • 3 - piperidine forMic acid
  • Piperidinecarboxylicaci
  • Nipecotic acid 98%
  • (R,S)-Piperidine-3-carboxylic acid
  • DL-Nip-OH
  • New Piperidine-3-carboxylic acid
  • 3-PiperidinecarboxylicAcid&gt
  • NIPECOTIC ACID CAS NO 498-95-3
  • Nipecotic acid ISO 9001：2015 REACH
  • 13C]-3-Piperidinecarboxylic acid
  • Nipecotic acid (6CI, 7CI, 8CI)
  • 3-Piperidine-3-CarboxylicAcid
  • 3-piperidine carboxylic acid (piperidine-3-carboxylic acid)
  • 498-95-3
  • 489-95-3