2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE

Product Name: 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE
CAS No.: 111686-79-4
Chemical Name: 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE
Synonyms: pr934-423a;fpl12924aa;RemacemideHCl;REMACEMIDE HYDROCHLORIDE;2-AMino-N-(1,2-diphenylpropan-2-yl)acetaMide hydrochloride;2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE;2-diphenylethyl)acetamidemonohydrochloride(+-)-2-amino-n-(1-methyl-;2-amino-n-(1-methyl-1,2-diphenylethyl)-,monohydrochloride,(+-)-acetamid
CBNumber: CB2360100
Molecular Formula: C17H21ClN2O
Formula Weight: 304.82
MOL File: 111686-79-4.mol

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2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Property

Melting point:: 253-254°
storage temp.: room temp
solubility: H2O: >10mg/mL
form: powder
color: white to beige
Water Solubility: Soluble to 100 mM in water

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Safety

Hazard Codes: Xn,N
Risk Statements: 22-41-50/53
Safety Statements: 26-39-45-60-61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3
RTECS: AB4349500
Toxicity: LD50 (calculated as base) in rats (mg/kg): ~50 i.v., ~900 orally (Muir, Palmer)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0335
Product name: Remacemide hydrochloride
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $144
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0335
Product name: Remacemide hydrochloride
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $540
Updated: 2023/01/07

Tocris

Product number: 1622
Product name: Remacemide hydrochloride
Purity: ≥99%(HPLC)
Packaging: 50
Price: $592
Updated: 2021/12/16

Tocris

Product number: 1622
Product name: Remacemide hydrochloride
Purity: ≥99%(HPLC)
Packaging: 10
Price: $140
Updated: 2021/12/16

TRC

Product number: R143450
Product name: Remacemide hydrochloride
Packaging: 2.5mg
Price: $140
Updated: 2021/12/16

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2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Anticonvulsant (neuroprotective).

Biological Activity

Non-competitive NMDA receptor antagonist; blocks ion channel and allosteric modulatory site (IC 50 = 8-68 mM). Anticonvulsant in vivo and metabolizes to a more potent desglycine analog. Weakly blocks voltage-dependent Na + channels (IC 50 = 161 mM).

Biochem/physiol Actions

Remacemide HCl is a low affinity NMDA antagonist with anticonvulsant properties. Remacemide also been shown to block voltage-dependent sodium channels.

2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Suppliers

China 12 Germany 1 India 2 South Korea 1 United Kingdom 2 United States 9 Global 27

3B Pharmachem (Wuhan) International Co.,Ltd.

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111686-79-4, 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDERelated Search:

2-AMINO-N-(TERT-BUTYL)ACETAMIDE HYDROCHLORIDE 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Ramacemide

REMACEMIDE HYDROCHLORIDE

2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE

RemacemideHCl

2-AMino-N-(1,2-diphenylpropan-2-yl)acetaMide hydrochloride

2-amino-n-(1-methyl-1,2-diphenylethyl)-,monohydrochloride,(+-)-acetamid

2-diphenylethyl)acetamidemonohydrochloride(+-)-2-amino-n-(1-methyl-

fpl12924aa

pr934-423a

111686-79-4