ChemicalBook > CAS DataBase List > 10,12-TRICOSADIYNOIC ACID

10,12-TRICOSADIYNOIC ACID

Product Name: 10,12-TRICOSADIYNOIC ACID
CAS No.: 66990-30-5
Chemical Name: 10,12-TRICOSADIYNOIC ACID
Synonyms: TIMTEC-BB SBB009036;10,12-Tricosadiynoicaci;10,12-TRICOSADIYNOIC ACID;tricosa-10,12-diynoic acid;10,12-Tricosadiynoic acid - [T94776];10,12-Tricosadiynoic acid >=98.0% (GC);10,12-TRICOSADIYNOIC ACID, 97%10,12-TRICOSADIYNOIC ACID, 97%10,12-TRICOSADIYNOIC ACID, 97%10,12-TRICOSADIYNOIC ACID, 97%;10,12-Tricosadiynoic acid,ROS,mono- acylglycerol acyltransferase,10,12Tricosadiynoic acid,fatty,Diacylglycerol acyltransferase,SIRT1-AMPK,Diglyceride acyltransferase,metabolic,mitochondrial,oxidation,insulin,10,12 Tricosadiynoic acid,inhibit,triglyceride,Inhibitor,Acyltransferase,acyl-CoA:cholesterol acyltransferase,acid
CBNumber: CB2360625
Molecular Formula: C23H38O2
Formula Weight: 346.55
MOL File: 66990-30-5.mol

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10,12-TRICOSADIYNOIC ACID Property

Melting point:: 56-60 °C
storage temp.: Refrigerator
solubility: DMSO : 100 mg/mL (288.56 mM）
form: Solid
color: White to off-white
Water Solubility: Insoluble in water.
Sensitive: Light Sensitive
BRN: 1880414
CAS DataBase Reference: 66990-30-5(CAS DataBase Reference)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 10-23
HS Code: 29161900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 91445
Product name: 10,12-Tricosadiynoic acid
Purity: ≥98.0% (GC)
Packaging: 5g
Price: $251.75
Updated: 2025/07/31

TCI Chemical

Product number: T1200
Product name: 10,12-Tricosadiynoic Acid
Purity: >98.0%(GC)(T)
Packaging: 100mg
Price: $14
Updated: 2021/12/16

TRC

Product number: T896460
Product name: 10,12-Tricosadiynoic acid
Packaging: 1mg
Price: $45
Updated: 2021/12/16

GFS CHEMICALS

Product number: 83105
Product name: 10,12-Tricosadiynoic acid
Packaging: 1g
Price: $50.73
Updated: 2021/12/16

GFS CHEMICALS

Product number: 83101
Product name: 10,12-Tricosadiynoic acid
Packaging: 5G
Price: $138.19
Updated: 2021/12/16

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10,12-TRICOSADIYNOIC ACID Chemical Properties,Usage,Production

Uses

It is an active pharmaceutical intermediate.

Definition

ChEBI: 10,12-tricosadiynoic acid is a very long-chain fatty acid.

in vivo

10,12-Tricosadiynoic acid (100 μg/kg; oral gavage; daily; for 8 weeks; male Wistar rats) treatment increases hepatic mitochondrial fatty acid oxidation (FAO) via activation of the SIRT1-AMPK (adenosine 5′-monophosphate-activated protein kinase) pathway and proliferator activator receptor α and reduces hydrogen peroxide accumulation in high fat diet-fed rats, which significantly decreases hepatic lipid and ROS contents, reduces body weight gain, and decreases serum triglyceride and insulin levels^[1].
10,12-Tricosadiynoic acid (0 mg/kg, 37.5 mg/kg, 75 mg/kg, and 150 mg/kg diet) treatment does not affect weight gain, but significantly decreases peroxisomal β-oxidation in the liver, and increased body fat accumulation in Nile tilapia. The fish with impaired peroxisomal β-oxidation exhibited higher contents of serum lipid and peroxidation products, and alanine aminotransferase activity, and significantly lowered hepatic activities of superoxide dismutase and catalase^[3].

Animal Model:	Male Wistar rats (210-230 g) fed with high fat diet^[1]
Dosage:	100 μg/kg
Administration:	Oral gavage; daily; for 8 weeks
Result:	Reduced hydrogen peroxide accumulation in high fat diet-fed rats, which significantly decreased hepatic lipid and ROS contents, reduced body weight gain, and decreased serum triglyceride and insulin levels.

10,12-TRICOSADIYNOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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10,12-TRICOSADIYNOIC ACID Suppliers

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66990-30-5, 10,12-TRICOSADIYNOIC ACIDRelated Search:

Propiolic Acid 10,12-NONACOSADIYNOIC ACID 10,12-HEPTACOSADIYNOIC ACID 10,12-PENTACOSADIYNOIC ACID, [2-3H] 10,12-PENTACOSADIYNOIC ACID 10,12-TRICOSADIYNOIC ACID METHYL 10,12-PENTACOSADIYNOATE 1,2-BIS(10,12-TRICOSADIYNOYL)-SN-GLYCERO-3-PHOSPHOETHANOLAMINE METHYL 10,12-TRICOSADIYNOATE

10,12-TRICOSADIYNOIC ACID

TIMTEC-BB SBB009036

tricosa-10,12-diynoic acid

10,12-Tricosadiynoic acid >=98.0% (GC)

10,12-TRICOSADIYNOIC ACID, 97%10,12-TRICOSADIYNOIC ACID, 97%10,12-TRICOSADIYNOIC ACID, 97%10,12-TRICOSADIYNOIC ACID, 97%

10,12-Tricosadiynoicaci

10,12-Tricosadiynoic acid,ROS,mono- acylglycerol acyltransferase,10,12Tricosadiynoic acid,fatty,Diacylglycerol acyltransferase,SIRT1-AMPK,Diglyceride acyltransferase,metabolic,mitochondrial,oxidation,insulin,10,12 Tricosadiynoic acid,inhibit,triglyceride,Inhibitor,Acyltransferase,acyl-CoA:cholesterol acyltransferase,acid

10,12-Tricosadiynoic acid - [T94776]

66990-30-5

6690-30-5

CH3CH29CCCCCH28CO2H

CH3CH29CCCCCH28COOH

Building Blocks

Carboxylic Acids

Carbonyl Compounds

C13 to C42+

Organic Building Blocks

Acetylenes

Diacetylene Monocarboxylic Acids

Acetylenic Carboxylic Acids & Their Derivatives

LB Films

Acetylenes

Acetylenic Carboxylic Acids & Their Derivatives

Diacetylene Monocarboxylic Acids

Functional Materials

LB Films