ChemicalBook > CAS DataBase List > 25-DESACETYL RIFAMPICIN

25-DESACETYL RIFAMPICIN

Product Name
25-DESACETYL RIFAMPICIN
CAS No.
16783-99-6
Chemical Name
25-DESACETYL RIFAMPICIN
Synonyms
Aids070669;Aids-070669;DeacetylrifaMpin;Desacetylrifampin;DeacetylrifaMpicin;Desacetylrifampicin;25-DesacetylrifaMpin;25-deacetylrifampicin;25-DESACEYL RIFAMYCIN;25-O-DesacetylrifaMpin
CBNumber
CB2365781
Molecular Formula
C41H56N4O11
Formula Weight
780.9
MOL File
16783-99-6.mol
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25-DESACETYL RIFAMPICIN Property

Melting point:
>300°C
Boiling point:
943.1±65.0 °C(Predicted)
Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
Amber Vial, -20°C Freezer, Under Inert Atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.96±0.70(Predicted)
color 
Dark Red to Black
Stability:
Light Sensitive
InChIKey
KUJZTIJOBQNKDR-ACYBWPGYNA-N
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Usbiological
Product number
D3219-15
Product name
Desacetyl Rifampicin
Packaging
1mg
Price
$425
Updated
2021/12/16
TRC
Product number
D288726
Product name
25-DesacetylRifampicin
Packaging
5mg
Price
$670
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000173
Product name
25-DESACETYL RIFAMPICIN
Purity
95.00%
Packaging
10MG
Price
$1732.5
Updated
2021/12/16
Adipogen Life Sciences
Product number
AG-CN2-0331-M050
Product name
RifamycinAMP-DA
Purity
≥95%(HPLC)
Packaging
50mg
Price
$480
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000173
Product name
25-DESACETYL RIFAMPICIN
Purity
95.00%
Packaging
1MG
Price
$292.95
Updated
2021/12/16
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25-DESACETYL RIFAMPICIN Chemical Properties,Usage,Production

Description

25-desacetyl rifampicin, also known as 25-deacetyl-rifampicin, is the main metabolite of rifampicin. It has partial activity. Rifampicin mainly treats various forms of tuberculosis. High-Performance Liquid Chromatographic can be used to determine the metabolism of rifampicin in the body by checking the concentration of 25-desacetyl rifampicin in the urine or blood of tuberculosis patients[1-3].

Chemical Properties

Dark Red Solid

Uses

A metabolite of Rifampicin.

References

[1]Chik Z, et al. A bioequivalence comparison of two formulations of rifampicin (300- vs 150-mg capsules): An open-label, randomized, two-treatment, two-way crossover study in healthy volunteers. Clinical Therapeutics, 2011.
[2] Mohan B, et al.Evaluation of the recently reported USP gradient HPLC method for analysis of anti-tuberculosis drugs for its ability to resolve degradation products of rifampicin. Journal of Pharmaceutical and Biomedical Analysis, 2003; 31: 607-612.
[3] Lily, et al. The influence of mutation gene rpoB of Mycobacterium tuberculosis cluster I (507-534) on the elimination 25-desacetyl rifampicin in urine of tuberculosis subjects. IOP Conference Series: Earth and Environmental Science, 2018; 1755-1315.

25-DESACETYL RIFAMPICIN Preparation Products And Raw materials

Raw materials

Preparation Products

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25-DESACETYL RIFAMPICIN Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
ProdList
96815
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76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
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15839
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Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
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50
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
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Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
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Cato Research Chemicals Inc.
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020-81960175
Fax
+1-541-2553641
Email
min.he@cato-chem.com
Country
China
ProdList
1955
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ChemStrong Scientific Co.,Ltd
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0755-0755-66853366 13670046396
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0755-28363542
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sales@chem-strong.com
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China
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Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9906
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50
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
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United States
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9923
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65
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
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58
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View Lastest Price from 25-DESACETYL RIFAMPICIN manufacturers

Guangzhou PI PI BIOTECH INC
Product
25-Desacetyl Rifampicin 16783-99-6
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
90%+
Supply Ability
10g
Release date
2021-09-20

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