ChemicalBook > CAS DataBase List > 25-DESACETYL RIFAMPICIN

25-DESACETYL RIFAMPICIN

Product Name
25-DESACETYL RIFAMPICIN
CAS No.
16783-99-6
Chemical Name
25-DESACETYL RIFAMPICIN
Synonyms
Aids070669;Aids-070669;DeacetylrifaMpin;Desacetylrifampin;DeacetylrifaMpicin;Desacetylrifampicin;25-DesacetylrifaMpin;25-deacetylrifampicin;25-DESACEYL RIFAMYCIN;25-O-DesacetylrifaMpin
CBNumber
CB2365781
Molecular Formula
C41H56N4O11
Formula Weight
780.9
MOL File
16783-99-6.mol
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25-DESACETYL RIFAMPICIN Property

Melting point:
>300°C
Boiling point:
943.1±65.0 °C(Predicted)
Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
Amber Vial, -20°C Freezer, Under Inert Atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.96±0.70(Predicted)
color 
Dark Red to Black
Stability:
Light Sensitive
InChIKey
KUJZTIJOBQNKDR-ACYBWPGYNA-N
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Usbiological
Product number
D3219-15
Product name
Desacetyl Rifampicin
Packaging
1mg
Price
$425
Updated
2021/12/16
TRC
Product number
D288726
Product name
25-DesacetylRifampicin
Packaging
5mg
Price
$670
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000173
Product name
25-DESACETYL RIFAMPICIN
Purity
95.00%
Packaging
10MG
Price
$1732.5
Updated
2021/12/16
Adipogen Life Sciences
Product number
AG-CN2-0331-M050
Product name
RifamycinAMP-DA
Purity
≥95%(HPLC)
Packaging
50mg
Price
$480
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000173
Product name
25-DESACETYL RIFAMPICIN
Purity
95.00%
Packaging
1MG
Price
$292.95
Updated
2021/12/16
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25-DESACETYL RIFAMPICIN Chemical Properties,Usage,Production

Description

25-desacetyl rifampicin, also known as 25-deacetyl-rifampicin, is the main metabolite of rifampicin. It has partial activity. Rifampicin mainly treats various forms of tuberculosis. High-Performance Liquid Chromatographic can be used to determine the metabolism of rifampicin in the body by checking the concentration of 25-desacetyl rifampicin in the urine or blood of tuberculosis patients[1-3].

Chemical Properties

Dark Red Solid

Uses

A metabolite of Rifampicin.

References

[1]Chik Z, et al. A bioequivalence comparison of two formulations of rifampicin (300- vs 150-mg capsules): An open-label, randomized, two-treatment, two-way crossover study in healthy volunteers. Clinical Therapeutics, 2011.
[2] Mohan B, et al.Evaluation of the recently reported USP gradient HPLC method for analysis of anti-tuberculosis drugs for its ability to resolve degradation products of rifampicin. Journal of Pharmaceutical and Biomedical Analysis, 2003; 31: 607-612.
[3] Lily, et al. The influence of mutation gene rpoB of Mycobacterium tuberculosis cluster I (507-534) on the elimination 25-desacetyl rifampicin in urine of tuberculosis subjects. IOP Conference Series: Earth and Environmental Science, 2018; 1755-1315.

25-DESACETYL RIFAMPICIN Preparation Products And Raw materials

Raw materials

Preparation Products

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25-DESACETYL RIFAMPICIN Suppliers

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J & K SCIENTIFIC LTD.
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View Lastest Price from 25-DESACETYL RIFAMPICIN manufacturers

Guangzhou PI PI BIOTECH INC
Product
25-Desacetyl Rifampicin 16783-99-6
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
90%+
Supply Ability
10g
Release date
2021-09-20

16783-99-6, 25-DESACETYL RIFAMPICINRelated Search:

25-DESACETYL RIFAMPICIN Rifampicin RIFAMPIN, [4-METHYLPIPERAZINE-3H]- RIFAMPICIN-N-OXID 25-DESACETYL RIFAPENTINE rifampicin N-oxide Rifapentine hydrochloride

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