ChemicalBook > CAS DataBase List > 3-BROMO-4-CHLOROQUINOLINE

3-BROMO-4-CHLOROQUINOLINE

Product Name: 3-BROMO-4-CHLOROQUINOLINE
CAS No.: 74575-17-0
Chemical Name: 3-BROMO-4-CHLOROQUINOLINE
Synonyms: 3-BROMO-4-CHLOROQUINOLINE;Quinoline, 3-bromo-4-chloro-;3-bromo-4-chloroquinoline(SALTDATA: FREE)
CBNumber: CB2371832
Molecular Formula: C9H5BrClN
Formula Weight: 242.5
MOL File: 74575-17-0.mol

Less

3-BROMO-4-CHLOROQUINOLINE Property

Melting point:: 69-70℃
Density: 1.673±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: solid
Appearance: White to off-white Solid

Less

Safety

Hazard Codes: T
Risk Statements: 25-41
Safety Statements: 26-39-45
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3
HS Code: 2933499090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: BBO000332
Product name: 3-Bromo-4-chloroquinoline
Purity: Aldrich
Packaging: 1g
Price: $286
Updated: 2025/07/31

AK Scientific

Product number: 1586AC
Product name: 3-Bromo-4-chloroquinoline
Packaging: 500mg
Price: $304
Updated: 2021/12/16

AK Scientific

Product number: 1586AC
Product name: 3-Bromo-4-chloroquinoline
Packaging: 250mg
Price: $204
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-D-15
Product name: 3-Bromo-4-chloroquinoline
Packaging: 1g
Price: $360
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0063398
Product name: 3-BROMO-4-CHLOROQUINOLINE
Purity: 95.00%
Packaging: 5G
Price: $1321.9
Updated: 2021/12/16

Less

3-BROMO-4-CHLOROQUINOLINE Chemical Properties,Usage,Production

Synthesis

68158-36-1

74575-17-0

The general procedure for the synthesis of 3-bromo-4-chloroquinoline using 3-bromoquinolin-4(1H)-one as starting material was as follows: phosphorochloridic acid (18.43 g, 0.12 mol) was added slowly and dropwise to a stirring suspension of 3-bromo-1H-quinolin-4-one (22.44 g, 0.10 mol) in acetonitrile (100 mL) at room temperature. The reaction mixture was heated to reflux for 7 hours. Upon completion of the reaction, the mixture was cooled to room temperature and slowly poured into crushed ice (400 mL). Subsequently, the pH of the mixture was adjusted with 10% potassium carbonate solution (220 mL) to 9. The resulting precipitate was collected by filtration, washed well with water and dried under vacuum. The final product was obtained as 3-bromo-4-chloroquinoline as a brown solid (22.58 g, 93% yield) with a melting point of 182-188 °C (literature values: 31 °C, 69-69.5 °C). The product was analyzed by 1H NMR (DMSO-d6, 400MHz) showing δ 9.08 (s, 1H), 8.25 (dd, 1H, J = 0.8, 8.4Hz), 8.12 (d, 1H, J = 8.0Hz), 7.95-7.89 (m, 1H), 7.86-7.80 (m, 1H); 13C NMR (DMSO-d6 , 400 MHz) analysis showed δ 151.6, 146.5, 140.2, 130.9, 129.5, 129.2, 126.4, 124.0, 117.7. The elemental analysis results are in accordance with the theoretical values of C9H5BrClN (molecular weight 242.50): C, 44.58; H, 2.08; N, 5.78; measured values: C 44.43; H, 2.09; N, 5.79. LCMS (ESI+) analysis showed m/z 242, 244 [M + H]+.

References

[1] Tetrahedron, 2013, vol. 69, # 45, p. 9512 - 9519
[2] Journal of Medicinal Chemistry, 2012, vol. 55, # 5, p. 1831 - 1843

3-BROMO-4-CHLOROQUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

3-BROMO-4-CHLOROQUINOLINE Suppliers

China 64 India 2 The Netherlands 1 United Kingdom 2 United States 9 Global 78

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 6387
Advantage: 52

Wuhan Haizheng Industry & Trade Development Co. Ltd

Tel: 027-8866 0053/88660577/88660578
Fax: 027-8899 1911
Country: China
ProdList: 1073
Advantage: 55

Chiba Pharmaceutical Science and technology Co, Ltd.

Tel: 0531-81313138 13066006660
Fax: QQ: 3366077777
Email: chibapharm@foxmail.com
Country: China
ProdList: 3991
Advantage: 55

Wuhan Taiyicheng Biopharmaceutical Co., Ltd.

Tel: 027-88320699
Fax: 027-88320962
Email: tycshyy@126.com
Country: China
ProdList: 297
Advantage: 66

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Shanghai Aspire Biological Technology Co., Ltd.

Tel: 021-61317773
Fax: 021-61486878
Email: sales@aspirebio.com
Country: China
ProdList: 2880
Advantage: 58

Modachem Shanghai Co., Ltd

Tel: +86 (0)21 51320687 51371369 1744605818
Fax: +86 (0)21 51371369
Country: China
ProdList: 1578
Advantage: 58

ShangHai AmK Pharmaceutical Technology Co., Ltd.

Tel: 微信 17321281695 18019252918
Fax: 17321281695
Email: sale@amkchem.com
Country: China
ProdList: 15136
Advantage: 55

NovoChemy Ltd.

Tel: 86-(0)21-31261262 373522135
Fax: 86-(0)21-33250524
Email: sales@novochemy.com
Country: China
ProdList: 6498
Advantage: 58

Shanghai Brain Biotechnology Co., Ltd.

Tel: 13564638271
Fax: 021-68948280
Email: shhjiang1977@163.com
Country: China
ProdList: 2987
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai QianYan Bio-technology Co., Ltd

Tel: 02781293128
Email: orders@biochemsafebuy.com
Country: China
ProdList: 9923
Advantage: 55

BePharm Ltd

Tel: 400-685-9117
Fax: 021-51816740
Email: market@bepharm.com
Country: China
ProdList: 15081
Advantage: 60

Suzhou JingTong Pharmaceutical Co., Ltd.

Tel: 13675155016
Fax: 18912765016
Email: tongtf110@sina.com
Country: China
ProdList: 963
Advantage: 55

Shijiazhuang Jing Kang Technology Co.Ltd.

Tel: 13933818572
Fax: 0311-82870388
Email: 1519554262@qq.com
Country: China
ProdList: 1785
Advantage: 58

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

Suzhou Nuoouman Biological Technology Co., Ltd.

Tel: 15026866316
Email: 180642609@qq.com
Country: China
ProdList: 4967
Advantage: 58

Changzhou Anchor Biological Technology Co., Ltd

Tel: 0519-85519868 18915088878
Fax: 0519-85512868
Email: sales@ankerbio.com
Country: China
ProdList: 261
Advantage: 58

Nanjing crow LuNing pharmaceutical technology co., LTD

Tel: 13382066392
Country: CHINA
ProdList: 4877
Advantage: 58

Guangdong wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2815688 13927872512
Fax: 0751-8963795
Email: 3007421951@qq.com
Country: China
ProdList: 9939
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Xinyi Kaiwu Chemical Technology Co., Ltd.

Tel: 0516-0516-88997009 18651776937
Email: 4164357@qq.com
Country: China
ProdList: 3204
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Amel Pharmatech Corporation

Tel: 027-888-4366503
Fax: 888-502-1736
Email: sales@amelpharmatech.com
Country: China
ProdList: 5000
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Huansheng Meisen Pharmaceutical Technology (Shandong) Co., Ltd

Tel: 0531-88762217 18301471076
Email: sales@acespharma.com
Country: China
ProdList: 3863
Advantage: 58

Wuhan Taiyicheng Biopharmaceutical Co., Ltd.

Tel: 027-88320699
Fax: 027-88320962
Email: tycshyy@126.com
Country: China
ProdList: 1000
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Hangzhou Taorui Biotechnology Co., Ltd

Tel: 4000-360-990 15268198094
Email: sales@torreybio.com
Country: China
ProdList: 3810
Advantage: 58

Ningbo jinuo chemical co., LTD

Tel: 0574-87314919 057487319282
Email: info@nbinno.com
Country: China
ProdList: 7047
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Shanghai Lingfu Pharmaceutical Research Co. LTD

Tel: +86(21)5895 0110 19945755304
Email: sales@chemany.com
Country: China
ProdList: 9984
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-55013243 15324716602
Email: 2853979810@qq.com
Country: China
ProdList: 9898
Advantage: 58

Changzhou Xinda Biotechnology Co., Ltd

Tel: 0519-85519868 18915088878
Email: xiaoweng106108@163.com
Country: China
ProdList: 99
Advantage: 58

Nanjing Pope Bio-tech R&D Co., Ltd

Tel: 025-87138562 18951783565
Email: sales@popebiotech.com
Country: China
ProdList: 1112
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 18621169109
Email: market03@meryer.com
Country: China
ProdList: 27987
Advantage: 58

Mancinor Technology Co., Ltd.

Tel: 19719236623
Email: 2885515945@qq.com
Country: China
ProdList: 1544
Advantage: 58

Shaanxi Xihua Chemical Industry Co., Ltd

Tel: 029-029-81123119 17391733320
Email: 1021@dideu.com
Country: China
ProdList: 10001
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Suzhou Qihang Biotechnology Co., Ltd

Tel: 18151111370
Email: 1046215251@qq.com
Country: China
ProdList: 8718
Advantage: 58

Zhuhai Aobokai Biomedical Technology Co., Ltd.

Tel: 400-0628126 15697567703
Email: sales-team@aobchem.com.cn
Country: China
ProdList: 49999
Advantage: 58

Less

View Lastest Price from 3-BROMO-4-CHLOROQUINOLINE manufacturers

Career Henan Chemical Co

Product: 3-BROMO-4-CHLOROQUINOLINE 74575-17-0
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-11

74575-17-0, 3-BROMO-4-CHLOROQUINOLINERelated Search:

λ-Cyhalothrin diloxanide 3-BROMO-4-CHLOROPYRIDINE HCL 4-CHLORO-3,6-DIBROMOQUINOLINE 3-BROMO-4,7-DICHLOROQUINOLINE 3-Bromoquinoline 3-BROMO-4-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE 3-BROMO-4-CHLOROQUINOLINE

3-BROMO-4-CHLOROQUINOLINE

3-bromo-4-chloroquinoline(SALTDATA: FREE)

Quinoline, 3-bromo-4-chloro-

74575-17-0