ChemicalBook > CAS DataBase List > 5-Nitro-6-methyluracil

5-Nitro-6-methyluracil

Product Name: 5-Nitro-6-methyluracil
CAS No.: 16632-21-6
Chemical Name: 5-Nitro-6-methyluracil
Synonyms: NSC 40201;6-Methyl-5-Nit;-5-nitropyrimidine;6-metyl-5-nitrouracil;6-methyl-5-nitrouracil;5-NITRO-6-METHYLURACIL;2,4-Dihydroxy-6-methyL;6-Methyl-5-nitrouracil >5-Nitro-6-methyluracil ,98%;2,4-Dihydroxy-6-methyl-5-Nitro
CBNumber: CB2373609
Molecular Formula: C5H5N3O4
Formula Weight: 171.11
MOL File: 16632-21-6.mol

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5-Nitro-6-methyluracil Property

Melting point:: 290-291°C dec.
Density: 1.58±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: DMF, DMSO, Hot Methanol, Hot Water
pka: 6.24±0.10(Predicted)
form: Solid
color: Light Yellow Crystalline
Water Solubility: Soluble in DMF, DMSO, hot methanol and hot water.
InChI: InChI=1S/C5H5N3O4/c1-2-3(8(11)12)4(9)7-5(10)6-2/h1H3,(H2,6,7,9,10)
InChIKey: LIVYMRJSNFHYEN-UHFFFAOYSA-N
SMILES: C1(=O)NC(C)=C([N+]([O-])=O)C(=O)N1
CAS DataBase Reference: 16632-21-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22-37/38-41-40
Safety Statements: 26-39-36-22
WGK Germany: 3
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M2506
Product name: 6-Methyl-5-nitrouracil
Purity: >95.0%(HPLC)(T)
Packaging: 1g
Price: $16
Updated: 2025/07/31

TCI Chemical

Product number: M2506
Product name: 6-Methyl-5-nitrouracil
Purity: >95.0%(HPLC)(T)
Packaging: 5g
Price: $33
Updated: 2025/07/31

Usbiological

Product number: 234348
Product name: 5-Nitro-6-methyluracil
Packaging: 5g
Price: $170
Updated: 2021/12/16

Usbiological

Product number: D3579-46
Product name: 2,4-Dihydroxy-6-methyl-5-nitropyrimidine
Packaging: 5g
Price: $375
Updated: 2021/12/16

TRC

Product number: D453250
Product name: 2,4-Dihydroxy-6-methyl-5-nitropyrimidine
Packaging: 50g
Price: $855
Updated: 2021/12/16

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5-Nitro-6-methyluracil Chemical Properties,Usage,Production

Chemical Properties

Light Yellow Crystalline Solid

Uses

A synthetic intermediate

Uses

5-Nitro-6-methyluracil, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Synthesis

626-48-2

16632-21-6

The general procedure for the synthesis of 2,4-dihydroxy-6-methyl-5-nitropyrimidine from 6-methyluracil was as follows: the procedure was adapted from the Journal of Medicinal Chemistry. 6-Methylpyrimidine-2,4(1H,3H)-dione (7.0 g, 55.56 mmol) was slowly added to ice-cooled but concentrated sulfuric acid (26 mL), and the rate of addition was controlled to keep the internal temperature of the reaction system from exceeding 40 °C. Subsequently, fuming nitric acid (5.2 mL) was slowly added dropwise to the reaction mixture at a temperature below 15 °C. After completion of the dropwise addition, the cooling bath was removed and the reaction mixture was stirred at room temperature for 30 min. The reaction solution was carefully poured into 100 mL of crushed ice and stirred for 10 minutes before collecting the solid product that precipitated. The solid was washed with cold water and then dried under vacuum in the presence of phosphorus pentoxide. A yellow-green solid of 6-methyl-5-nitropyrimidine-2,4(1H,3H)-dione (7.92 g, 83% yield) was finally obtained.

References

[1] Journal of Chemical Research, Miniprint, 1989, # 9, p. 2086 - 2097
[2] Patent: WO2009/62258, 2009, A1. Location in patent: Page/Page column 97-98
[3] Synthetic Communications, 2007, vol. 37, # 14, p. 2421 - 2431
[4] ChemMedChem, 2018, vol. 13, # 2, p. 178 - 185
[5] Patent: CN105906621, 2016, A. Location in patent: Paragraph 0030

5-Nitro-6-methyluracil Preparation Products And Raw materials

Raw materials

6-Methyluracil Ethyl acetoacetate Ethanol Diethyl ether Hydrochloric acid Nitric acid Phosphorus pentoxide Sulfuric acid UREA HYDROCHLORIDE Potassium nitrate

Preparation Products

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View Lastest Price from 5-Nitro-6-methyluracil manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 5-Nitro-6-methyluracil 16632-21-6
Price: US $2.00-5.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-20

Honest Joy Holdings Limited

Product: 2,4-Dihydroxy-6-methyl-5-nitropyrimidine 16632-21-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.7%
Supply Ability: 100 tons
Release date: 2022-02-08

Dideu Industries Group Limited

Product: 5-Nitro-6-methyluracil 16632-21-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-14

16632-21-6, 5-Nitro-6-methyluracilRelated Search:

METSULFURON METHYL Triclosan 1,3-Dihydroxyacetone Bensulfuron methyl Methyl acetate 4,6-Dihydroxypyrimidine 1-Hydroxyethylidene-1,1-diphosphonic acid 6-Methyluracil Methylparaben 4-Ethyl-5-fluoro-6-hydroxypyrimidine Butylated Hydroxytoluene Uracil 5-Nitrouracil DINITROTOLUENE Pirimiphos-methyl Methyl salicylate Thiophanate-methyl Kresoxim-methyl

5-NITRO-6-METHYLURACIL

2,4-DIHYDROXY-5-NITRO-6-METHYLPYRIMIDINE

2,4-DIHYDROXY-6-METHYL-5-NITROPYRIMIDINE

6-METHYL-5-NITROPYRIMIDINE-2,4-DIOL

6-metyl-5-nitrouracil

6-methyl-5-nitrouracil

6-Methyl-5-Nitrouracil 5-Nitro-6-Methyluracil

5-NITRO-6-METHYLURACIL5 6-METHYL-5-NITROPYRIMIDINE-2,4-DIOL 2,4-DIHYDROXY-6-METHYL-5-NITROPYRIMIDINE

6-Methyl-5-nitro-1H-pyrimidine-2,4-dione

2,4-Dihydroxy-6-methyl-5-Nitro

2,4(1H,3H)-Pyrimidinedione, 6-methyl-5-nitro-

6-Methyl-5-nitropyrimidine-2,4-dione

5-Nitro-6-methyluracil ,98%

4-Dihydroxy-6-Methyl-5-nitropyriMidine

2,4-Dihydroxy-6-Methyl-5-nitropyriMidine

NSC 40201

6-methyl-5-nitro-1,2,3,4-tetrahydropyrimidine-2,4-dione

6-Methyl-5-Nit

6-Methyl-5-nitrouracil &gt

2,4-Dihydroxy-6-methyL

-5-nitropyrimidine

5-Nitro-6-methyluracil ISO 9001：2015 REACH

16632-21-6

C5H5N3O4

Bases & Related Reagents

Nucleotides

Nucleotides and Nucleosides

Pyrimidines

Heterocycles