(E)-2-Butenoyl chloride

Product Name: (E)-2-Butenoyl chloride
CAS No.: 625-35-4
Chemical Name: (E)-2-Butenoyl chloride
Synonyms: (E)-But-2-enoyl chloride;CROTONYL CHLORIDE;CrotonoyL;Einecs 210-889-9;(E)-CH3CH=CHCOCl;CROTONIC CHLORIDE;E-Crotonoylchloride;E-CROTONYL CHLORIDE;2-Crotonoyl chloride;(E)-2-Butenoyl chlor
CBNumber: CB2381592
Molecular Formula: C4H5ClO
Formula Weight: 104.53
MOL File: 625-35-4.mol

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(E)-2-Butenoyl chloride Property

Melting point:: 72-74 °C
Boiling point:: 120-123 °C(lit.)
Density: 1.091 g/mL at 25 °C(lit.)
refractive index: n20/D 1.459(lit.)
Flash point:: 95 °F
storage temp.: 2-8°C
form: Liquid
color: Clear colorless to brown
Water Solubility: Reacts with water.
Sensitive: Moisture Sensitive
BRN: 506118
InChI: InChI=1S/C4H5ClO/c1-2-3-4(5)6/h2-3H,1H3/b3-2+
InChIKey: RJUIDDKTATZJFE-NSCUHMNNSA-N
SMILES: C(Cl)(=O)/C=C/C
CAS DataBase Reference: 625-35-4(CAS DataBase Reference)
NIST Chemistry Reference: 2-Butenoyl chloride, (E)-(625-35-4)

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Safety

Hazard Codes: C
Risk Statements: 10-34-36/37-37
Safety Statements: 16-26-27-36/37/39-45-28A-24/25
RIDADR: UN 2920 8/PG 2
WGK Germany: 3
F: 13-19-21
TSCA: Yes
HazardClass: 8
PackingGroup: II
HS Code: 29161900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 127787
Product name: Crotonoyl chloride
Purity: technical grade, 90%
Packaging: 5g
Price: $90.9
Updated: 2025/07/31

Sigma-Aldrich

Product number: 127787
Product name: Crotonoyl chloride
Purity: technical grade, 90%
Packaging: 100g
Price: $316
Updated: 2025/07/31

Sigma-Aldrich

Product number: 127787
Product name: Crotonoyl chloride
Purity: technical grade, 90%
Packaging: 500g
Price: $552
Updated: 2023/06/20

TRC

Product number: C818810
Product name: Crotonoyl chloride
Packaging: 1g
Price: $120
Updated: 2021/12/16

TRC

Product number: C818810
Product name: Crotonoyl chloride
Packaging: 10g
Price: $165
Updated: 2021/12/16

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(E)-2-Butenoyl chloride Chemical Properties,Usage,Production

Chemical Properties

clear colourless to brown liquid

Uses

Crotonyl chloride is used in agrochemical, pharmaceutical and dyestuff field. Crotonoyl chloride was used in the synthesis of α,β-unsaturated ester.

Synthesis

107-93-7

625-35-4

Preparation of Raw Materials; 1-1 :(Preparation of Crotonyl chloride) Firstly, 1kg of crotonic acid was added to a 5L three-necked reaction flask fitted with a condenser and gas absorption device. Under slow stirring, 1650 mL (1.5 mol) of thionyl chloride was slowly added through a constant pressure dropping funnel, and a large amount of hydrogen chloride gas was released during the reaction. Stirring was continued at room temperature until the gas release slowed down significantly. Subsequently, the reaction mixture was slowly heated to reflux. Upon completion of the reaction, the unit was changed to a distillation unit for atmospheric pressure distillation and the 116-124 °C fraction was collected to give 871 g of crotonyl chloride in 72% yield.

Purification Methods

If the IR of a film has no OH bands, then fractionally distil it, taking the middle fraction and redistilling it. If OH bands are present, then add excess of oxalyl chloride, reflux for 3hours, then distil off the reagent and fractionally distil the crotonoyl chloride as before. Stabilise the distillate with 160ppm of hydroquinone. The amide forms needles m 158o from aqueous ammonia, and the anilide also forms needles but with m 115-118o from H2O. [Beilstein 2 H 411, 2 I 188, 2 II 392, 2 III 1265, 2 IV 1506.]

References

[1] Journal of Organometallic Chemistry, 1987, vol. 322, p. 131 - 140
[2] Journal of Organic Chemistry, 2009, vol. 74, # 22, p. 8739 - 8753
[3] Patent: US2012/165532, 2012, A1. Location in patent: Page/Page column 3
[4] Helvetica Chimica Acta, 1985, vol. 68, p. 1406 - 1426
[5] Journal of Organic Chemistry USSR (English Translation), 1981, vol. 17, # 11, p. 2072 - 2075

(E)-2-Butenoyl chloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(E)-2-Butenoyl chloride Suppliers

Belgium 1 China 173 Germany 2 India 2 Switzerland 1 United Kingdom 3 United States 8 Global 190

Hebei Liye Chemical Products Co., Ltd

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Alfa Aesar

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Shanghai Hanhong Scientific Co.,Ltd.

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Shandong Xiya Chemical Co., Ltd

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View Lastest Price from (E)-2-Butenoyl chloride manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: (E)-2-Butenoyl chloride 625-35-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-11-25

Career Henan Chemical Co

Product: (E)-2-Butenoyl chloride 625-35-4
Price: US $7.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-21

625-35-4, (E)-2-Butenoyl chlorideRelated Search:

SULFOXIDE Isobutylene Octanoyl chloride Crotonic acid Crotonyl chloride 2-Butenoyl chloride -Methacryloyl chloride CROTONYL CHLORIDE,E-CROTONYL CHLORIDE Methacryloyl chloride

TRANS-CROTONYL CHLORIDE

Crotonyl chloride, 90+%, remainder mainly cis-isomer

2-Butenoyl chloride, (E)-

Crotonoyl chloride (E)-

Einecs 210-889-9

(E)-2-Butenoyl chlor

Crotonyl Chloride, ReMainder Mainly Cis-IsoMer

CrotonoyL

2-Crotonoyl chloride

trans-Crotonoyl Chloride

E-Crotonoylchloride

Crotonoyl chloride technical grade, 90%

CROTONYL CHLORIDE

CROTONIC ACID CHLORIDE

E-CROTONYL CHLORIDE

(e)-2-butenoylchlorid

(E)-2-Butenoylchloride

(E)-CH3CH=CHCOCl

TRANS-CROTONYL CHLORIDE, TECH., 90%

Crotonyl chloride, tech., 90%

trans-Crotonylchloride,tech.90%

trans-Crotonyl chloride, 90+%, remainder mainly cis-isomer

TRANS-2-BUTENOYL CHLORIDE

(E)-But-2-enoyl chloride

Trans-crotonyl chloride, 90%, tech.

(E)-2-Butenoic acid chloride

trans-Crotonic acid chloride

E-Crotonoyl chloride,>90%

2-Butenoyl chloride, (2E)-

rans-Crotonylchloride

CROTONIC CHLORIDE

625-35-4

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