Description References
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HEMATIN

Description References
Product Name
HEMATIN
CAS No.
15489-90-4
Chemical Name
HEMATIN
Synonyms
heme;haem;HEMATIN;HEMATEIN;Hematins;phenodin;HAEMATIN;ferriheme;ferrihemate;Hematin BR
CBNumber
CB2390068
Molecular Formula
C34H31FeN4O5-
Formula Weight
631.49
MOL File
15489-90-4.mol
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HEMATIN Property

Melting point:
180 °C
storage temp. 
2-8°C
solubility 
DMF (Slightly), DMSO (Slightly, Heated, Sonicated), Pyridine (Slightly, Heated,
form 
solid
color 
Black
Merck 
14,4635
Stability:
Light Sensitive
LogP
7.193 (est)
CAS DataBase Reference
15489-90-4
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Safety

WGK Germany 
3
RTECS 
NO6725000
HS Code 
2934999090
Toxicity
LD50 i.v. in rats: 4.32 mg/100 g (Lips)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H3281
Product name
Hematin porcine
Packaging
1g
Price
$66.4
Updated
2024/03/01
Sigma-Aldrich
Product number
H3281
Product name
Hematin porcine
Packaging
5g
Price
$189
Updated
2024/03/01
Sigma-Aldrich
Product number
H3281
Product name
Hematin porcine
Packaging
250mg
Price
$62.9
Updated
2024/03/01
Sigma-Aldrich
Product number
H3281
Product name
Hematin porcine
Packaging
10g
Price
$335
Updated
2024/03/01
Apolloscientific
Product number
BIB6063
Product name
Hematin porcine
Packaging
1g
Price
$87
Updated
2021/12/16
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HEMATIN Chemical Properties,Usage,Production

Description

Produced from red blood cells, Hematin is a bluish-black or brownish pigment compound derived from hemoglobin by removal of the protein part and oxidation of the iron atom from ferrous Fe2+ to the ferric Fe3+ state, which does not combine with oxygen. It is effective to inhibit the synthesis of porphyrin and, at the same time, stimulate the synthesis of globin. It involves in the formation of cytochromes and peroxidases in the cell. Hematin is also a pharmaceutical used in the treatment of porphyria, which can be administered intravenously to halt the attack of acute porphyria. It functions in the liver to accelerate the production of heme and thus preventing the further accumulation of heme precursors, porphyrins, which is effective to alleviate the symptoms of porphyria.

References

https://en.wikipedia.org/wiki/Haematin
http://house.wikia.com/wiki/Hematin
https://en.oxforddictionaries.com/definition/us/hematin
http://medical-dictionary.thefreedictionary.com/hematin

Chemical Properties

Dark crystals with metalic luster

Uses

Indicator, biological stain.

Uses

Hematin was used in a study to test in vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. It was also used in a study to test in-vitro bacterial identification using fluorescence spectroscopy with an optical fiber system.

Definition

The hydroxide of heme. Not to be confused with hematein.

Purification Methods

Crystallise it from pyridine. Dry it at 40o in vacuo.[Beilstein 26 III/IV 3047.]

HEMATIN Preparation Products And Raw materials

Raw materials

Preparation Products

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HEMATIN Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7583
Advantage
55
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
Advantage
60
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4647
Advantage
58
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4941
Advantage
60
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9725
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
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View Lastest Price from HEMATIN manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
HEMATIN 15489-90-4
Price
US $70.00-18.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-09-08
Hebei Guanlang Biotechnology Co., Ltd.
Product
HEMATIN 15489-90-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-10-14
Wuhan wingroup Pharmaceutical Co., Ltd
Product
Hematin
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000kg
Release date
2021-08-23

15489-90-4, HEMATINRelated Search:


  • 2-))-hydroxy-
  • ferrihemate
  • ferriheme
  • ferrihemehydroxide
  • ferrihemicacid
  • HEMATEIN
  • HEMATIN PORCINE
  • HYDROXYHEMIN
  • dihydrogen hydroxy[3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24]ferrate(2-)
  • heme
  • HEMATIN FROM PORCINE
  • Ferrate(2-), 7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-.kappa.N21,.kappa.N22,.kappa.N23,.kappa.N24hydroxy-, dihydrogen, (SP-5-13)-
  • haem
  • dihydrogen hydroxy[3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24]ferrate(2-)
  • [Dihydrogen 3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato(2-)]hydroxyiron
  • Hematins
  • Ferrate(2-),[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-kN21,kN22,kN23,kN24]hydroxy-, hydrogen (1:2),(SP-5-13)-
  • ferriporphyrinhydroxide
  • ferriprotoporphyrinbasic
  • ferriprotoporphyrinixhydroxide
  • hydroxy(dihydrogenprotoporphyrinix-ato(2-))iron
  • iron,(dihydrogen3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato(
  • phenodin
  • protohematin
  • BOVINE HEMIN
  • HAEMATIN
  • HEMATIN
  • Hematin BR
  • 15489-90-4
  • C34H33N4O5Fe
  • C34H33FeN4O5
  • C34H32FeN4O4FeOH
  • C34H31FeN4O52H
  • BioChemical
  • Biochemicals and Reagents
  • Application Index
  • Enzymes, Inhibitors, and Substrates
  • Serum Proteins and Related Enzymes
  • Serum Proteins
  • HematinApplication Index
  • Plasma&Blood Proteins
  • Plasma, Blood, and Related Proteins and Reagents
  • Serum Proteins
  • Serum Proteins and Related Enzymes