ChemicalBook > CAS DataBase List > HEMATIN

HEMATIN

Description References

Product Name: HEMATIN
CAS No.: 15489-90-4
Chemical Name: HEMATIN
Synonyms: heme;haem;HEMATIN;HEMATEIN;Hematins;phenodin;HAEMATIN;ferriheme;ferrihemate;Hematin BR
CBNumber: CB2390068
Molecular Formula: C34H31FeN4O5-
Formula Weight: 631.49
MOL File: 15489-90-4.mol

Less

HEMATIN Property

Melting point:: 180 °C
storage temp.: 2-8°C
solubility: DMF (Slightly), DMSO (Slightly, Heated, Sonicated), Pyridine (Slightly, Heated,
form: solid
color: Black
biological source: Porcine
Merck: 14,4635
Stability:: Light Sensitive
LogP: 7.193 (est)
CAS DataBase Reference: 15489-90-4

Less

Safety

WGK Germany: 3
RTECS: NO6725000
HS Code: 2934999090
Toxicity: LD50 i.v. in rats: 4.32 mg/100 g (Lips)

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H3281
Product name: Hematin porcine
Packaging: 1g
Price: $68.1
Updated: 2025/07/31

Sigma-Aldrich

Product number: H3281
Product name: Hematin porcine
Packaging: 5g
Price: $204
Updated: 2025/07/31

Sigma-Aldrich

Product number: H3281
Product name: Hematin porcine
Packaging: 250mg
Price: $67.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: H3281
Product name: Hematin porcine
Packaging: 10g
Price: $343
Updated: 2025/07/31

Apolloscientific

Product number: BIB6063
Product name: Hematin porcine
Packaging: 1g
Price: $87
Updated: 2021/12/16

Less

HEMATIN Chemical Properties,Usage,Production

Description

Produced from red blood cells, Hematin is a bluish-black or brownish pigment compound derived from hemoglobin by removal of the protein part and oxidation of the iron atom from ferrous Fe2+ to the ferric Fe3+ state, which does not combine with oxygen. It is effective to inhibit the synthesis of porphyrin and, at the same time, stimulate the synthesis of globin. It involves in the formation of cytochromes and peroxidases in the cell. Hematin is also a pharmaceutical used in the treatment of porphyria, which can be administered intravenously to halt the attack of acute porphyria. It functions in the liver to accelerate the production of heme and thus preventing the further accumulation of heme precursors, porphyrins, which is effective to alleviate the symptoms of porphyria.

References

https://en.wikipedia.org/wiki/Haematin
http://house.wikia.com/wiki/Hematin
https://en.oxforddictionaries.com/definition/us/hematin
http://medical-dictionary.thefreedictionary.com/hematin

Chemical Properties

Dark crystals with metalic luster

Uses

Indicator, biological stain.

Uses

Hematin was used in a study to test in vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens.It was also used in a study to test in-vitro bacterial identification using fluorescence spectroscopy with an optical fiber system.

Definition

The hydroxide of heme. Not to be confused with hematein.

Biological Activity

Hematin is a hydroxide of heme. It may be used to tre at acute porphyric attacks. Hematin suppresses the hepatic aminolevulinic acid (ALA) function and replenishes cytochrome action by restoring the endogenous heme deficit. Early administration of hematin can prevent irreversible neuronal damage induced due to metabolic disorders.

Purification Methods

Crystallise it from pyridine. Dry it at 40o in vacuo.[Beilstein 26 III/IV 3047.]

HEMATIN Preparation Products And Raw materials

Raw materials

Preparation Products

Less

HEMATIN Suppliers

China 114 Europe 2 Germany 2 India 3 Japan 1 South Korea 1 Switzerland 3 United Kingdom 3 United States 15 Global 144

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 7247
Advantage: 62

Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
Fax: 021-57711696
Email: marketing_china@spectrumchemical.com
Country: China
ProdList: 9658
Advantage: 60

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4747
Advantage: 58

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4999
Advantage: 60

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Shanghai Ruji Biology Technology Co., Ltd.

Tel: +86-21-65211385-8001 36031160
Fax: +86-21-65211385-8004
Email: sales@shruji.com
Country: China
ProdList: 3224
Advantage: 55

Suzhou yacoo science co.,Ltd

Tel: 0512-87182056 18013166090
Fax: 0512-87182056
Email: lingling.qi@yacoo.com.cn
Country: China
ProdList: 6295
Advantage: 60

Shanghai Xingui Biotechnology Co., Ltd.

Tel: 15121041756
Email: xingui2022@126.com
Country: China
ProdList: 9986
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15873
Advantage: 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Watson Biotechnology Co.,Ltd

Tel: 027-59207879 1972026995 18140587686
Fax: QQ：1972026995
Email: sales@3600chem.com
Country: China
ProdList: 4446
Advantage: 55

Beijing NuoqiYa Biotechnology Co., Ltd.

Tel: 4000-819-385 010-62329685 13718666987
Fax: 010-62340519
Country: China
ProdList: 1971
Advantage: 55

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Shanghai Xilong Biochemical Technology Co., Ltd.

Tel: 021-52907766-8042
Fax: 021-52906523
Country: China
ProdList: 9941
Advantage: 58

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20794
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Anhui kuer Bioengineering Co., Ltd

Tel: 0551-65171243 13856024262
Email: kuer@kuerhuaxue.com
Country: China
ProdList: 2992
Advantage: 55

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 9998
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 021-021-52271985 17721149837
Fax: +86 (21) 52271987
Email: sales@9dingchem.com
Country: China
ProdList: 19800
Advantage: 60

Wuhan Netcom Electronic Commerce Limited

Tel: 18064670521
Fax: 0757-88210752
Email: 2355935187@ycphar.com
Country: China
ProdList: 4879
Advantage: 58

Xi'an boliante Chemical Co., Ltd.

Tel: 17719597442
Fax: -
Email: 642232259@qq.com
Country: China
ProdList: 449
Advantage: 58

Guangzhou LES biological Technology Co.,Ltd.

Tel: 13672434928
Fax: -
Email: 3307355104@qq.com
Country: China
ProdList: 3650
Advantage: 58

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Beijing OKA biological technology co., LTD

Tel: 010-62971590 18548936886
Fax: 010-62340519
Email: 3462612863@qq.com
Country: China
ProdList: 10063
Advantage: 58

Hubei Dibai Chemical Co., Ltd.

Tel: 027-87058617 15872383390
Fax: 027-87058617
Email: hbdibo@163.com
Country: China
ProdList: 856
Advantage: 58

Guangzhou Belka Biological Technology Co., Ltd.

Tel: +86-18665676617
Fax: 18665676617
Country: China
ProdList: 957
Advantage: 58

Macheng jinxin biotechnology co., LTD

Tel: 18271582018
Email: 1126319697@qq.com
Country: China
ProdList: 1527
Advantage: 58

ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23541
Advantage: 58

Hebei Yanxi Chemical Co., Ltd.

Tel: +8618531123677
Email: faithe@yan-xi.com
Country: China
ProdList: 5853
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 20284
Advantage: 58

ShanDong Look Chemical Co.,Ltd.

Tel: +8617653113219
Email: sales01@sdlookchemical.com
Country: China
ProdList: 2768
Advantage: 58

Wuhan wingroup Pharmaceutical Co., Ltd

Tel: +86-13296627870; +8613296627870
Fax: 0086-27-87819568
Email: info@whwingroup.com
Country: China
ProdList: 695
Advantage: 58

Shanghai Hongshun Biological Technology Co., Ltd.

Tel: 15901914505 15901914505;
Fax: 021-54389085
Email: 3187892335@qq.com
Country: China
ProdList: 9889
Advantage: 58

Guangdong Wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2886766 13927870850
Fax: 0751-2886756
Email: 3001267247@qq.com
Country: China
ProdList: 9941
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39927
Advantage: 58

Shanghai jingkang bioengineering co., ltd.

Tel: 021-54721350 13524668266
Fax: 021-5
Email: 2881505714@qq.com
Country: China
ProdList: 7872
Advantage: 58

Shanghai Kanglang Biotechnology Co., Ltd.

Tel: 021-61998208 18217752821
Fax: 021-37680378
Email: sales@klbio.cn
Country: China
ProdList: 9621
Advantage: 58

Shaanxi Chenming Biotechnology Co., Ltd

Tel: 15332367321
Email: 2709392183@qq.com
Country: China
ProdList: 1076
Advantage: 58

Shandong Pingju Biotechnology Co., Ltd

Tel: 18613662662
Email: 2708672464@qq.com
Country: China
ProdList: 1144
Advantage: 58

Shandong Nayazuo Chemical Technology Co. LTD

Tel: 400-873-6778 18660992876
Fax: 0539-6267369
Email: 3584419101@qq.com
Country: China
ProdList: 4970
Advantage: 58

Lingyuan Bebiansen Biological Technology Co., Ltd

Tel: 18642120371
Email: 2837458851@qq.com
Country: China
ProdList: 7963
Advantage: 58

Shandong Tianming Biotechnology Development Co. Ltd

Tel: 400-9019001
Country: China
ProdList: 15069
Advantage: 58

Tianjin Guangfu Technology Development Co. LTD

Tel: 022-85689490 13132141716
Email: sales@guangfubiaowu.com
Country: China
ProdList: 1630
Advantage: 58

Less

View Lastest Price from HEMATIN manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: HEMATIN 15489-90-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-28

Hebei Yanxi Chemical Co., Ltd.

Product: HEMATIN 15489-90-4
Price: US $70.00-18.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-09-08

Wuhan wingroup Pharmaceutical Co., Ltd

Product: Hematin
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5000kg
Release date: 2021-08-23

15489-90-4, HEMATINRelated Search:

HEMATIN HYDROCHLORIDE,Hematin chloride HEMATEIN,HEMATEIN FOR MICROSCOPY,HEMATEIN FROM LOGWOOD,HEMATEIN C.I. 75290 FOR MICROSCOPY,HEMATEIN, STAIN hematin-protei 2,4-Dimethylpyrrole 2,3,4,5-TETRAMETHYLPYRROLE Allylacetic acid 6-Heptenoic acid 3-BUTEN-1-AMINE HEMATIN 4-HEXENOIC ACID N-PROPYLETHYLIDENEAMINE 3-METHYL-2-BUTEN-1-AMINE 5-METHYL-4-HEXENOIC ACID 1,3,6-HEPTATRIENE AMMONIUM HEMATEIN,HEMATEIN-AMMONIUM 3-ETHYL-2-METHYL-2-PENTENE HEPTA-4,6-DIENOIC ACID 2,4-OCTADIENE

2-))-hydroxy-

ferrihemate

ferriheme

ferrihemehydroxide

ferrihemicacid

HEMATEIN

HEMATIN PORCINE

HYDROXYHEMIN

dihydrogen hydroxy[3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24]ferrate(2-)

heme

HEMATIN FROM PORCINE

Ferrate(2-), 7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-.kappa.N21,.kappa.N22,.kappa.N23,.kappa.N24hydroxy-, dihydrogen, (SP-5-13)-

haem

dihydrogen hydroxy[3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24]ferrate(2-)

[Dihydrogen 3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato(2-)]hydroxyiron

Hematins

Ferrate(2-),[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-kN21,kN22,kN23,kN24]hydroxy-, hydrogen (1:2),(SP-5-13)-

ferriporphyrinhydroxide

ferriprotoporphyrinbasic

ferriprotoporphyrinixhydroxide

hydroxy(dihydrogenprotoporphyrinix-ato(2-))iron

iron,(dihydrogen3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato(

phenodin

protohematin

BOVINE HEMIN

HAEMATIN

HEMATIN

Hematin BR

dihydrogen hydroxy[3,8,13,17-tetramethyl-7,12-divinyl-21H,23...

Hematin, Iron-containing porphyrin

0WP180G15G 15489-90-4 Hematin Dihydrogen hydroxy(3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24)ferrate(2-) Iron, (dihydrogen 3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato(2-))-hydroxy- Bovine hemin EINECS 239-518-9 Ferrihemate Ferriheme Ferriheme hydroxide Ferrihemic acid Ferriporphyrin hydroxide Ferriprotoporphyrin basic Ferriprotoporphyrin IX hydroxide Hydroxy(dihydrogen protoporphyrin IX-ato(2-))iron Hydroxyhemin Phenodin Protohematin UNII-0WP180G15G

0WP180G15G 15489-90-4 Hematin Dihydrogen hydroxy(3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24)ferrate(2-) Iron, (dihydrogen 3,7,12,17-tetramethyl-8,13-

15489-90-4

C34H33N4O5Fe

C34H33FeN4O5

C34H32FeN4O4FeOH

C34H31FeN4O52H

BioChemical

Biochemicals and Reagents

Application Index

Enzymes, Inhibitors, and Substrates

Serum Proteins and Related Enzymes

Serum Proteins

HematinApplication Index

Plasma&Blood Proteins

Plasma, Blood, and Related Proteins and Reagents

Serum Proteins

Serum Proteins and Related Enzymes