Description References
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HEMATIN

Description References
Product Name
HEMATIN
CAS No.
15489-90-4
Chemical Name
HEMATIN
Synonyms
heme;haem;HEMATIN;HEMATEIN;Hematins;phenodin;HAEMATIN;ferriheme;ferrihemate;Hematin BR
CBNumber
CB2390068
Molecular Formula
C34H31FeN4O5-
Formula Weight
631.49
MOL File
15489-90-4.mol
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HEMATIN Property

Melting point:
180 °C
storage temp. 
2-8°C
solubility 
DMF (Slightly), DMSO (Slightly, Heated, Sonicated), Pyridine (Slightly, Heated,
form 
solid
color 
Black
Merck 
14,4635
Stability:
Light Sensitive
LogP
7.193 (est)
CAS DataBase Reference
15489-90-4
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Safety

WGK Germany 
3
RTECS 
NO6725000
HS Code 
2934999090
Toxicity
LD50 i.v. in rats: 4.32 mg/100 g (Lips)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H3281
Product name
Hematin porcine
Packaging
1g
Price
$66.4
Updated
2024/03/01
Sigma-Aldrich
Product number
H3281
Product name
Hematin porcine
Packaging
5g
Price
$189
Updated
2024/03/01
Sigma-Aldrich
Product number
H3281
Product name
Hematin porcine
Packaging
250mg
Price
$62.9
Updated
2024/03/01
Sigma-Aldrich
Product number
H3281
Product name
Hematin porcine
Packaging
10g
Price
$335
Updated
2024/03/01
Apolloscientific
Product number
BIB6063
Product name
Hematin porcine
Packaging
1g
Price
$87
Updated
2021/12/16
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HEMATIN Chemical Properties,Usage,Production

Description

Produced from red blood cells, Hematin is a bluish-black or brownish pigment compound derived from hemoglobin by removal of the protein part and oxidation of the iron atom from ferrous Fe2+ to the ferric Fe3+ state, which does not combine with oxygen. It is effective to inhibit the synthesis of porphyrin and, at the same time, stimulate the synthesis of globin. It involves in the formation of cytochromes and peroxidases in the cell. Hematin is also a pharmaceutical used in the treatment of porphyria, which can be administered intravenously to halt the attack of acute porphyria. It functions in the liver to accelerate the production of heme and thus preventing the further accumulation of heme precursors, porphyrins, which is effective to alleviate the symptoms of porphyria.

References

https://en.wikipedia.org/wiki/Haematin
http://house.wikia.com/wiki/Hematin
https://en.oxforddictionaries.com/definition/us/hematin
http://medical-dictionary.thefreedictionary.com/hematin

Chemical Properties

Dark crystals with metalic luster

Uses

Indicator, biological stain.

Uses

Hematin was used in a study to test in vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. It was also used in a study to test in-vitro bacterial identification using fluorescence spectroscopy with an optical fiber system.

Definition

The hydroxide of heme. Not to be confused with hematein.

Purification Methods

Crystallise it from pyridine. Dry it at 40o in vacuo.[Beilstein 26 III/IV 3047.]

HEMATIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from HEMATIN manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
HEMATIN 15489-90-4
Price
US $70.00-18.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-09-08
Hebei Guanlang Biotechnology Co., Ltd.
Product
HEMATIN 15489-90-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-10-14
Wuhan wingroup Pharmaceutical Co., Ltd
Product
Hematin
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000kg
Release date
2021-08-23

15489-90-4, HEMATINRelated Search:


  • 2-))-hydroxy-
  • ferrihemate
  • ferriheme
  • ferrihemehydroxide
  • ferrihemicacid
  • HEMATEIN
  • HEMATIN PORCINE
  • HYDROXYHEMIN
  • dihydrogen hydroxy[3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24]ferrate(2-)
  • heme
  • HEMATIN FROM PORCINE
  • Ferrate(2-), 7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-.kappa.N21,.kappa.N22,.kappa.N23,.kappa.N24hydroxy-, dihydrogen, (SP-5-13)-
  • haem
  • dihydrogen hydroxy[3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24]ferrate(2-)
  • [Dihydrogen 3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato(2-)]hydroxyiron
  • Hematins
  • Ferrate(2-),[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-kN21,kN22,kN23,kN24]hydroxy-, hydrogen (1:2),(SP-5-13)-
  • ferriporphyrinhydroxide
  • ferriprotoporphyrinbasic
  • ferriprotoporphyrinixhydroxide
  • hydroxy(dihydrogenprotoporphyrinix-ato(2-))iron
  • iron,(dihydrogen3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato(
  • phenodin
  • protohematin
  • BOVINE HEMIN
  • HAEMATIN
  • HEMATIN
  • Hematin BR
  • 15489-90-4
  • C34H33N4O5Fe
  • C34H33FeN4O5
  • C34H32FeN4O4FeOH
  • C34H31FeN4O52H
  • BioChemical
  • Biochemicals and Reagents
  • Application Index
  • Enzymes, Inhibitors, and Substrates
  • Serum Proteins and Related Enzymes
  • Serum Proteins
  • HematinApplication Index
  • Plasma&Blood Proteins
  • Plasma, Blood, and Related Proteins and Reagents
  • Serum Proteins
  • Serum Proteins and Related Enzymes