ChemicalBook > CAS DataBase List > METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE

METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE

Product Name: METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE
CAS No.: 81452-54-2
Chemical Name: METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE
Synonyms: RARECHEM AL BF 0178;3-Methylthiophene-2-Cabroxylate;3-methylthiophene-2-carboxylate;Methyl 3-methylthienyl-2-carboxylate;Eethyl3-methylthiophene-2-carboxylate;METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE;Methyl 3-Methylthiophene-2-carboxylate >Methyl 3-methylthiophene-2-carboxylate ,99%;3-Methylthiophen-2-carboxylic acid methyl ester;3-methyl-2-thiophenecarboxylic acid methyl ester
CBNumber: CB2390952
Molecular Formula: C7H8O2S
Formula Weight: 156.2
MOL File: 81452-54-2.mol

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METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE Property

Boiling point:: 216-217°C
Density: 1.173±0.06 g/cm3(Predicted)
refractive index: 1.5168
Flash point:: 216-217°C
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: clear liquid
color: Colorless to Light yellow
BRN: 116836
InChI: InChI=1S/C7H8O2S/c1-5-3-4-10-6(5)7(8)9-2/h3-4H,1-2H3
InChIKey: BRWROFVPMUPMJQ-UHFFFAOYSA-N
SMILES: C1(C(OC)=O)SC=CC=1C

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Safety

Safety Statements: 23-24/25
HS Code: 29151300

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: M2662
Product name: Methyl 3-Methylthiophene-2-carboxylate
Purity: >97.0%(GC)
Packaging: 1g
Price: $27
Updated: 2025/07/31

TCI Chemical

Product number: M2662
Product name: Methyl 3-Methylthiophene-2-carboxylate
Purity: >97.0%(GC)
Packaging: 5g
Price: $79
Updated: 2025/07/31

TRC

Product number: M219630
Product name: Methyl 3-Methylthiophene-2-carboxylate
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: OR953363
Product name: Methyl 3-Methylthiophene-2-carboxylate
Purity: 96%
Packaging: 5g
Price: $90
Updated: 2021/12/16

AK Scientific

Product number: W8584
Product name: Methyl 3-Methylthiophene-2-carboxylate
Packaging: 10g
Price: $90
Updated: 2021/12/16

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METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid

Synthesis

67-56-1

23806-24-8

81452-54-2

Step 1: Synthesis of methyl 3-methylthiophene-2-carboxylate: 3-methylthiophene-2-carboxylic acid (15 g, 105 mmol, 1.0 eq.) was dissolved in methanol (150 mL) and concentrated sulfuric acid (7.5 mL) was added slowly and dropwise. The reaction mixture was heated to reflux for 12 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in ethyl acetate (200 mL) and washed sequentially with water (2 x 50 mL), saturated aqueous sodium bicarbonate solution (2 x 50 mL) and brine (50 mL). The organic phase was dried with anhydrous sodium sulfate, filtered, and the filtrate was concentrated under reduced pressure to afford 20 g (97% yield) of methyl 3-methylthiophene-2-carboxylate as an oil. The product was confirmed by 1H NMR (400 MHz, CDCl3): δ 7.38 (d, J=5.0 Hz, 1H), 6.91 (d, J=5.0 Hz, 1H), 3.85 (s, 3H), 2.55 (s, 3H); ESI-MS m/z 157 ([M+H]+).

References

[1] Patent: WO2012/56478, 2012, A1. Location in patent: Page/Page column 75-76
[2] Patent: WO2007/124546, 2007, A1. Location in patent: Page/Page column 58
[3] Patent: WO2014/64131, 2014, A2. Location in patent: Page/Page column 114; 115
[4] Patent: WO2014/76104, 2014, A1. Location in patent: Page/Page column 79-80
[5] Journal of Medicinal Chemistry, 1995, vol. 38, # 24, p. 4806 - 4820

METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Acetone Chromium(VI) oxide Methanol 3-Methyl-2-thiophenecarboxaldehyde Sulfuric acid

Preparation Products

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METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE Suppliers

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View Lastest Price from METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE 81452-54-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-11-26

Shanghai UCHEM Inc.

Product: Methyl 3-methylthiophene-2-carboxylate 81452-54-2
Price: US $47.00-679.00/g
Min. Order: 25g
Purity: 0.98
Supply Ability: 25kg
Release date: 2023-12-22

Shaanxi Dideu Medichem Co. Ltd

Product: 3-methylthiophene-2-carboxylate 81452-54-2
Price: US $0.10-1.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 50tons
Release date: 2020-04-24

81452-54-2, METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATERelated Search:

DIETHYL 3,4-DIMETHYLTHIENO[2,3-B]THIOPHENE-2,5-DICARBOXYLATE DIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE METHYL 4-METHYLTHIOPHENE-2-CARBOXYLATE 3-Methylthiophene 3-Methyl-2-thiophenecarboxylic acid METHYL THIOPHENE-2-CARBOXYLATE 2-Thiophenecarboxylic acid 3-METHYLBENZO[B]THIOPHENE ETHYL 3-(BENZYLTHIO)-6,6-DIMETHYL-4-OXO-4,5,6,7-TETRAHYDROBENZO[C]THIOPHENE-1-CARBOXYLATE ETHYL 3-(METHYLTHIO)-4-OXO-4,5,6,7-TETRAHYDROBENZO[C]THIOPHENE-1-CARBOXYLATE ETHYL 5-CYANO-3,4-DIMETHYLTHIENO[2,3-B]THIOPHENE-2-CARBOXYLATE ETHYL 5-METHYL-3-(METHYLTHIO)-4,4-DIOXO-4,5-DIHYDRO-4LAMBDA6-BENZO[C]THIENO[3,4-E][1,2]THIAZINE-1-CARBOXYLATE METHYL 3-(5-FORMYL-2-FURYL)THIOPHENE-2-CARBOXYLATE ETHYL 3-(BUTYLTHIO)-4-OXO-4,5,6,7-TETRAHYDROBENZO[C]THIOPHENE-1-CARBOXYLATE ETHYL 3-(ALLYLTHIO)-4-OXO-4,5,6,7-TETRAHYDROBENZO[C]THIOPHENE-1-CARBOXYLATE ETHYL 4-ACETYL-3-METHYL-5-(METHYLTHIO)THIOPHENE-2-CARBOXYLATE METHYL 4-[(4-CHLOROPHENYL)SULFONYL]-3-METHYLTHIOPHENE-2-CARBOXYLATE ETHYL 3-(BENZYLTHIO)-4-OXO-4,5,6,7-TETRAHYDROBENZO[C]THIOPHENE-1-CARBOXYLATE

METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE

RARECHEM AL BF 0178

3-Methylthiophene-2-carboxylic acid methyl ester

Methyl 3-methylthiophene-2-carboxylate ,99%

3-Methylthiophene-2-Cabroxylate

Eethyl3-methylthiophene-2-carboxylate

3-methylthiophene-2-carboxylate

3-methyl-2-thiophenecarboxylic acid methyl ester

Methyl 3-Methylthiophene-2-carboxylate &gt

2-Thiophenecarboxylic acid, 3-methyl-, methyl ester

METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE ISO 9001：2015 REACH

Methyl 3-methylthienyl-2-carboxylate

Methyl 3-methylthiophene-2-carboxylate , Methyl 3-methyl-thiophene-2-carboxylate

3-Methylthiophen-2-carboxylic acid methyl ester

81452-54-2