ChemicalBook > CAS DataBase List > 4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE

4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE

Product Name
4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE
CAS No.
426844-51-1
Chemical Name
4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE
Synonyms
4,4-Difluoro-l-prolinaMide, HCl;4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE;(2S)-4,4-difluoropyrrolidine-2-carboxamide;(S)-4,4-difluoropyrrolidine-2-carboxamide HCl;(2S)-4,4-difluoro-2-pyrrolidinecarboxamide, HCl;(2S)-4,4-difluoro-L-proline amide hydrochloride;4,4-Difluoro-L-prolinamide hydrochloride;-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride;(S)-4,4-difluoropyrrolidine-2-carboxamide hydrochloride;(2S)-4,4-difluoropyrrolidine-2-carboxamide hydrochloride
CBNumber
CB2391898
Molecular Formula
C5H9ClF2N2O
Formula Weight
186.59
MOL File
426844-51-1.mol
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4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE Property

Melting point:
222°C
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Pale Grey to Light Grey
optical activity
[α]/D 23±5°, c = 0.5 in H2O
InChI
InChI=1/C5H8F2N2O.ClH/c6-5(7)1-3(4(8)10)9-2-5;/h3,9H,1-2H2,(H2,8,10);1H/t3-;/s3
InChIKey
RRQDQYAEZGKHOB-OQFXAWDINA-N
SMILES
C1[C@@H](C(N)=O)NCC1(F)F.Cl |&1:1,r|
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
HS Code 
2933998090
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
717061
Product name
4,4-Difluoro-L-prolinamide hydrochloride
Purity
97%
Packaging
500mg
Price
$79.1
Updated
2025/07/31
TRC
Product number
D451325
Product name
4,4-Difluoro-L-prolinamide hydrochloride
Packaging
2.5g
Price
$645
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0012766
Product name
4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE
Purity
95.00%
Packaging
1G
Price
$715.52
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD50537
Product name
4,4-Difluoro-L-prolinamide hydrochloride
Packaging
5G
Price
$720
Updated
2021/12/16
Chem-Impex
Product number
16507
Product name
4,4-Difluoro-L-prolinamidehydrochloride,99%(HPLC)
Purity
99%(HPLC)
Packaging
5G
Price
$408.8
Updated
2021/12/16
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4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

4,4-Difluoro-L-prolinamide hydrochloride can be used as a building block in the synthesis of cyanopyrrolidine based DPP-IV inhibitors.

4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE Suppliers

Jiangxi Kaixin Biomedical Co., Ltd.
Tel
0797-2111676 18890136722
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sales@chiralsyn.com
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China
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Shanghai Lingfu Pharmaceutical Research Co. LTD
Tel
+86(21)5895 0110 19945755304
Email
sales@chemany.com
Country
China
ProdList
9984
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58
Aikon International Limited
Tel
025-58859352 18921922613
Email
hywu@aikonchem.com
Country
China
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Shanghai AQ BioPharma Co., Ltd.
Tel
13512160998
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sales@aqbiopharma.com.cn
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China
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Alfa Aesar
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400-6106006
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021-67582001/03/05
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saleschina@alfa-asia.com
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China
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30123
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Bide Pharmatech Ltd.
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400-400-164-7117 18317119277
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+86-21-61629029
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product02@bidepharm.com
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China
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Shanghai AQBioPharma Co., Ltd.
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51370935-8011
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Shanghai Synteam Biochem CO.,ltd
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Sigma-Aldrich
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021-61415566 800-8193336
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Tongling HengYou Biotechnology Co., Ltd.
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426844-51-1, 4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDERelated Search:


  • (2S)-4,4-difluoropyrrolidine-2-carboxamide hydrochloride
  • 4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE
  • -4,4-Difluoropyrrolidine-2-carboxamide hydrochloride
  • 4,4-Difluoro-l-prolinaMide, HCl
  • (S)-4,4-difluoropyrrolidine-2-carboxamide hydrochloride
  • (S)-4,4-difluoropyrrolidine-2-carboxamide HCl
  • (2S)-4,4-difluoro-2-pyrrolidinecarboxamide, HCl
  • (2S)-4,4-difluoropyrrolidine-2-carboxamide
  • (2S)-4,4-difluoro-L-proline amide hydrochloride
  • 4,4-Difluoro-<sc>L</sc>-prolinamide hydrochloride
  • 426844-51-1
  • 26844-51-1
  • C5H8F2N2OHCl
  • HClC5H8N2OF2
  • C5H8F2N2OClH