TALAMPICILLIN
- Product Name
- TALAMPICILLIN
- CAS No.
- 47747-56-8
- Chemical Name
- TALAMPICILLIN
- Synonyms
- C11751;TALAMPICILLIN;TALAMPICILLIN USP/EP/BP;Ampicillin phthalidyl ester;3-Phthalidyl D-2-amino-2-phenylacetamidopenicillanic acid;(6R)-6-[[(R)-2-Amino-2-phenylacetyl]amino]penicillanic acid 1,3-dihydro-3-oxoisobenzofuran-1-yl ester;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester, [2S-[2a,5a,6b(S*)]]-;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester, (2S,5R,6R)-;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester, (2S,5R,6R)- (9CI)
- CBNumber
- CB2403465
- Molecular Formula
- C24H23N3O6S
- Formula Weight
- 481.52
- MOL File
- 47747-56-8.mol
TALAMPICILLIN Property
- Boiling point:
- 770.9±60.0 °C(Predicted)
- Density
- 1.48±0.1 g/cm3(Predicted)
- pka
- 12.15±0.60(Predicted)
N-Bromosuccinimide Price
- Product number
- API0012556
- Product name
- TALAMPICILLIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.44
- Updated
- 2021/12/16
TALAMPICILLIN Chemical Properties,Usage,Production
Originator
Talpen,Beecham,US,1975
Uses
Antibacterial.
Definition
ChEBI: Talampicillin is a penicillanic acid ester that is the 1-phthalidyl ester of ampicillin. It is a prodrug of ampicillin. It has a role as a prodrug. It is functionally related to an ampicillin and an o-phthalaldehydic acid.
Manufacturing Process
A fine suspension of 25.18 grams (0.05 mol) of potassium salt of enamine protected ampicillin and 10.65 grams (0.05 mol) 3-bromophthalide were reacted in a 1:2 mixture of acetone/ethyl acetate (1,500 ml) for 24 hours. After filtration the organic layer was washed twice with 250 ml portions of 1 N sodium bicarbonate and brine, dried over anhydrous magnesium sulfate and concentrated in vacuo. Addition of ether crystallized the phthalide enamine protected α-aminophenylacetamido penicillanate in 85% yield.
Therapeutic Function
Antibacterial
TALAMPICILLIN Preparation Products And Raw materials
Raw materials
Preparation Products
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