L-(-)-VESAMICOL HYDROCHLORIDE

Product Name: L-(-)-VESAMICOL HYDROCHLORIDE
CAS No.: 112709-59-8
Chemical Name: L-(-)-VESAMICOL HYDROCHLORIDE
Synonyms: L(-)-VESAMICOL HCL;1r-trans-cyclohexano;L-(-)-VESAMICOL HYDROCHLORIDE;(1R,2R)-2-(4-phenylpiperidin-1-yl)cyclohexan-1-ol;Cyclohexanol, 2-(4-phenyl-1-piperidinyl)-, (1R,2R)-;L-(-)-2-(4-Phenylpiperidino)cyclohexanol hydrochloride
CBNumber: CB2407498
Molecular Formula: C17H25NO
Formula Weight: 259.39
MOL File: 112709-59-8.mol

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L-(-)-VESAMICOL HYDROCHLORIDE Property

Melting point:: 238.5-240.0 °C
Boiling point:: 393.5±42.0 °C(Predicted)
Density: 1.086±0.06 g/cm3(Predicted)
pka: 15.16±0.40(Predicted)
form: solid
color: white

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
RTECS: GW0765050

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Hazard and Precautionary Statements (GHS)

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L-(-)-VESAMICOL HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

(-)-Vesamicol (AH5183) is an inhibitor of acetylcholine transport into synaptic vesicles, with the IC50 of 75 nM[1]. (-)-Vesamicol can be used for release and recycling of synaptic vesicles study[1].

Definition

ChEBI: (1R,2R)-2-(4-phenyl-1-piperidinyl)-1-cyclohexanol is a member of piperidines.

References

[1] Searl T, et al. Acetylcholine recycling and release at rat motor nerve terminals studied using (-)-vesamicol and troxpyrrolium. J Physiol. 1991;444:99-116. DOI:10.1113/jphysiol.1991.sp018868

L-(-)-VESAMICOL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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L-(-)-VESAMICOL HYDROCHLORIDE Suppliers

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112709-59-8, L-(-)-VESAMICOL HYDROCHLORIDERelated Search:

2-Aminocyclohexanol (R)-2-Aminocyclohenanol TRANS-2-AMINOCYCLOHEXANOL HYDROCHLORIDE N,N-Dimethylcyclohexylamine 1-CYCLOHEXYLPIPERIDINE N,N-DIETHYLCYCLOHEXYLAMINE 2-METHYLAMINO-CYCLOHEXANOL (+/-)-VESAMICOL HYDROCHLORIDE (1S,2S)-2-AMINOCYCLOHEXANOL (1R,2R)-2-(ETHYLAMINO)CYCLOHEXANOL TRANS-2-METHYLAMINO-CYCLOHEXANOL HYDROCHLORIDE (1R,2R)-2-(PROPYLAMINO)CYCLOHEXANOL [1S,2R]-trans-2-Aminocyclohexanol hydrochloride (+/-)-VESAMICOL HYDROCHLORIDE,(+/-)-VESAMICOL HYDROCHLORIDE (AH-5183) >98% CHEMBRDG-BB 4003161 2-PIPERIDIN-1-YL-CYCLOHEXANOL L-(-)-VESAMICOL HYDROCHLORIDE D(+)-VESAMICOL HYDROCHLORIDE

L-(-)-VESAMICOL HYDROCHLORIDE

1r-trans-cyclohexano

L(-)-VESAMICOL HCL

L-(-)-2-(4-Phenylpiperidino)cyclohexanol hydrochloride

(1R,2R)-2-(4-phenylpiperidin-1-yl)cyclohexan-1-ol

Cyclohexanol, 2-(4-phenyl-1-piperidinyl)-, (1R,2R)-

112709-59-8

C17H25NOHCl