17-PHENYL TRINOR PROSTAGLANDIN E2 Property

Boiling point:

597.1±50.0 °C(Predicted)

Density 

1?+-.0.06 g/cm3(Predicted)

RTECS 

MJ9681060

solubility 

DMF: >100 mg/ml (from Fluprostenol); DMSO: >100 mg/ml (from Fluprostenol); Ethanol: >100 mg/ml (from Fluprostenol); PBS pH 7.2: >0.8 mg/ml (from 17-phenyl tri

pka

4.75±0.10(Predicted)

form 

Oil

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

17-PHENYL TRINOR PROSTAGLANDIN E2 Chemical Properties,Usage,Production

Uses

17-Phenyl-trinor-prostaglandin E2 is a synthetic analog of PGE2 and an agonist at the EP1 and EP3 receptor (1). Prostaglandin E2(PGE2) regulates neuroinflammatory responses and is upregulated in brain injury by cyclooxygenase 2 (COX-?2) and membrane-bound PGE synthase. 17-Phenyl-trinor-prostaglandin E2 can be used to investigate inflammatory signaling pathways (2).

Definition

ChEBI: 17-phenyl-18,19,20-trinor-prostaglandin E2 is a prostanoid that is 18,19,20-trinor-prostaglandin E2 in which one of the terminal methyl hydrogens has been replaced by a phenyl group. It has a role as a human metabolite and a prostaglandin receptor agonist. It is a prostanoid, an alicyclic ketone, a beta-hydroxy ketone, a secondary alcohol, an oxo monocarboxylic acid, a hydroxy monocarboxylic acid and an olefinic compound.