17-PHENYL TRINOR PGF2ALPHA-IPR

Product Name: 17-PHENYL TRINOR PGF2ALPHA-IPR
CAS No.: 130209-76-6
Chemical Name: 17-PHENYL TRINOR PGF2ALPHA-IPR
Synonyms: 13-trans-Latanoprost;Sparsentan Impurity 17;Bimatoprost isopropyl este;imatoprost isopropyl ester;Bimatoprost isopropyl ester;17-PHENYL TRINOR PGF2ALPHA-IPR;Bimatoprost Acid Isopropyl Ester;17-phenyl trinor PGF2α isopropyl ester;17-phenyl trinor PGF2alpha isopropyl ester;17-phenyl trinor Prostaglandin F2α isopropyl ester
CBNumber: CB2459437
Molecular Formula: C26H38O5
Formula Weight: 430.58
MOL File: 130209-76-6.mol

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17-PHENYL TRINOR PGF2ALPHA-IPR Property

Boiling point:: 573.4±50.0 °C(Predicted)
Density: 1.141
storage temp.: Store at -20°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 50 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 1 mg/ml
pka: 14.25±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H360May damage fertility or the unborn child

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 16824
Product name: 17-phenyl trinor Prostaglandin F2α isopropyl ester
Purity: ≥98%
Packaging: 1mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 16824
Product name: 17-phenyl trinor Prostaglandin F2α isopropyl ester
Purity: ≥98%
Packaging: 5mg
Price: $324
Updated: 2024/03/01

Cayman Chemical

Product number: 16824
Product name: 17-phenyl trinor Prostaglandin F2α isopropyl ester
Purity: ≥98%
Packaging: 10mg
Price: $575
Updated: 2024/03/01

AHH

Product number: MT-21382
Product name: 17-PhenyltrinorPgf2alpha-Ipr
Purity: 98%
Packaging: 0.01g
Price: $345
Updated: 2021/12/16

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17-PHENYL TRINOR PGF2ALPHA-IPR Chemical Properties,Usage,Production

Description

17-phenyl trinor PGF_2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost. The N-ethyl amide prostaglandin prodrugs are converted to the active free acid more slowly than the analogous prostaglandin ester prodrugs such as latanoprost. This product is the isopropyl ester of the free acid prostaglandin which corresponds to Bimatoprost. The free acid, 17-phenyl trinor PGF_2α, is a potent FP receptor agonist. In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity. The 17-phenyl trinor PGF_2α isopropyl ester derivative was examined for IOP-lowering activity during the development of latanoprost. At the dose of 3 μg/eye in the monkey, 17-phenyl trinor PGF_2α isopropyl ester was the most potent analog tested in reducing IOP, lowering the IOP 1.3 mm Hg below the level achieved by latanoprost. However, this derivative was also significantly more irritating to the eye than latanoprost.

Uses

PhDH 100A can be useful in the determination of prostaglandin analogs in cosmetic products by high performance liquid chromatography with tandem mass spectrometry.

Definition

ChEBI: 17-phenyl-trinor-PGF2alpha isopropyl ester is a prostanoid.

17-PHENYL TRINOR PGF2ALPHA-IPR Preparation Products And Raw materials

Raw materials

Preparation Products

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17-PHENYL TRINOR PGF2ALPHA-IPR Suppliers

Canada 1 China 40 India 2 Switzerland 1 United Kingdom 1 United States 6 USA 1 Global 52

Taizhou Crene Biotechnology Co. Ltd.

Tel: +86-0576-88813233 +86-13396860566
Email: sales@pharm-intermediates.com
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ProdList: 1990
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Taizhou KEDE Chemical Co., Ltd

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Fax: 0576-84613060
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Eastbang Pharmaceuticals Technology Co., Ltd.

Tel: +86 (20) 28996708,29078958,28139708,29076128,28133708,28139728,28139738,28133718,021-31663278,021-31663578,021-60538387
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Taizhou Crene Biotechnology Co., Ltd.

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Hubei Jusheng Technology Co.,Ltd

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BOC Sciences

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Shanghai EFE Biological Technology Co., Ltd.

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Amadis Chemical Company Limited

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Hubei Yangxin Medical Technology Co., Ltd.

Tel: 15374522761
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Chengdu Saiousi Pharmaceutical Co., Ltd

Tel: 028-64971018 18108168130
Fax: 86 028-64971018
Country: China
ProdList: 1781
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View Lastest Price from 17-PHENYL TRINOR PGF2ALPHA-IPR manufacturers

Career Henan Chemical Co

Product: 17-PHENYL TRINOR PGF2ALPHA-IPR 130209-76-6
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200KG
Release date: 2019-07-01

130209-76-6, 17-PHENYL TRINOR PGF2ALPHA-IPRRelated Search:

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17-PHENYL TRINOR PGF2ALPHA-IPR

(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-5-heptenoic acid propan-2-yl ester

7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic acid 1-methylethyl ester

Bimatoprost isopropyl ester

17-phenyl trinor Prostaglandin F2α isopropyl ester

17-phenyl trinor PGF2α isopropyl ester

isopropyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enoate

propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoate

Bimatoprost isopropyl este

imatoprost isopropyl ester

17-phenyl trinor PGF2alpha isopropyl ester

Bimatoprost Acid Isopropyl Ester

5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)-

13-trans-Latanoprost

isopropyl phenylhydroxypentene dihydroxycyclopentylheptenate

17-phenyl trinor Prostaglandin F2α isopropyl ester

Sparsentan Impurity 17

130209-76-6

C26H38O5