ChemicalBook > CAS DataBase List > 17-PHENYL TRINOR PGF2ALPHA-IPR

17-PHENYL TRINOR PGF2ALPHA-IPR

Product Name
17-PHENYL TRINOR PGF2ALPHA-IPR
CAS No.
130209-76-6
Chemical Name
17-PHENYL TRINOR PGF2ALPHA-IPR
Synonyms
13-trans-Latanoprost;Sparsentan Impurity 17;Bimatoprost isopropyl este;imatoprost isopropyl ester;Bimatoprost isopropyl ester;17-PHENYL TRINOR PGF2ALPHA-IPR;Bimatoprost Acid Isopropyl Ester;17-phenyl trinor PGF2α isopropyl ester;17-phenyl trinor PGF2alpha isopropyl ester;17-phenyl trinor Prostaglandin F2α isopropyl ester
CBNumber
CB2459437
Molecular Formula
C26H38O5
Formula Weight
430.58
MOL File
130209-76-6.mol
More
Less

17-PHENYL TRINOR PGF2ALPHA-IPR Property

Boiling point:
573.4±50.0 °C(Predicted)
Density 
1.141
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 50 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 1 mg/ml
pka
14.25±0.20(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
16824
Product name
17-phenyl trinor Prostaglandin F2α isopropyl ester
Purity
≥98%
Packaging
1mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
16824
Product name
17-phenyl trinor Prostaglandin F2α isopropyl ester
Purity
≥98%
Packaging
5mg
Price
$324
Updated
2024/03/01
Cayman Chemical
Product number
16824
Product name
17-phenyl trinor Prostaglandin F2α isopropyl ester
Purity
≥98%
Packaging
10mg
Price
$575
Updated
2024/03/01
AHH
Product number
MT-21382
Product name
17-PhenyltrinorPgf2alpha-Ipr
Purity
98%
Packaging
0.01g
Price
$345
Updated
2021/12/16
More
Less

17-PHENYL TRINOR PGF2ALPHA-IPR Chemical Properties,Usage,Production

Description

17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost. The N-ethyl amide prostaglandin prodrugs are converted to the active free acid more slowly than the analogous prostaglandin ester prodrugs such as latanoprost. This product is the isopropyl ester of the free acid prostaglandin which corresponds to Bimatoprost. The free acid, 17-phenyl trinor PGF2α, is a potent FP receptor agonist. In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity. The 17-phenyl trinor PGF2α isopropyl ester derivative was examined for IOP-lowering activity during the development of latanoprost. At the dose of 3 μg/eye in the monkey, 17-phenyl trinor PGF2α isopropyl ester was the most potent analog tested in reducing IOP, lowering the IOP 1.3 mm Hg below the level achieved by latanoprost. However, this derivative was also significantly more irritating to the eye than latanoprost.

Uses

PhDH 100A can be useful in the determination of prostaglandin analogs in cosmetic products by high performance liquid chromatography with tandem mass spectrometry.

Definition

ChEBI: 17-phenyl-trinor-PGF2alpha isopropyl ester is a prostanoid.

17-PHENYL TRINOR PGF2ALPHA-IPR Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

17-PHENYL TRINOR PGF2ALPHA-IPR Suppliers

Canada 1 China 40 India 2 Switzerland 1 United Kingdom 1 United States 6 USA 1 Global 52
Taizhou Crene Biotechnology Co. Ltd.
Tel
+86-0576-88813233 +86-13396860566
Email
sales@pharm-intermediates.com
Country
China
ProdList
1990
Advantage
58
Taizhou KEDE Chemical Co., Ltd
Tel
0576-84613060 13093829633
Fax
0576-84613060
Email
sales@kedechemical.com
Country
China
ProdList
298
Advantage
60
Eastbang Pharmaceuticals Technology Co., Ltd.
Tel
+86 (20) 28996708,29078958,28139708,29076128,28133708,28139728,28139738,28133718,021-31663278,021-31663578,021-60538387
Fax
+86 (20) 39218032
Country
China
ProdList
454
Advantage
58
Taizhou Crene Biotechnology Co., Ltd.
Tel
0576-88813233 88205808
Fax
0576-88229589
Email
sales@taizhoukerui.com
Country
China
ProdList
137
Advantage
57
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
Advantage
58
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Hubei Yangxin Medical Technology Co., Ltd.
Tel
15374522761
Fax
QQ:2853117752
Email
3003392093@qq.com
Country
China
ProdList
8377
Advantage
55
Chengdu Saiousi Pharmaceutical Co., Ltd
Tel
028-64971018 18108168130
Fax
86 028-64971018
Country
China
ProdList
1781
Advantage
55
Shanghai Genriver Pharmaceutical Co., Ltd.
Tel
21-13482015261-883 13482015261
Fax
+86-21-37782903
Email
info@genriverpharm.com
Country
China
ProdList
444
Advantage
58
Nanjing crow LuNing pharmaceutical technology co., LTD
Tel
13382066392
Country
CHINA
ProdList
4877
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd
Tel
0571-85361029
Fax
0571-85361029
Email
synstar518@163.com
Country
China
ProdList
1990
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418684 +8618949823763
Fax
0086-551-65418684
Email
sales@tnjchem.com
Country
China
ProdList
25356
Advantage
58
sgtlifesciences pvt ltd
Tel
+8617013299288
Email
dj@sgtlifesciences.com
Country
China
ProdList
12373
Advantage
58
Hubei Ipure Biology Co., Ltd
Tel
+8613367258412
Fax
18062427325
Email
ada@ipurechemical.com
Country
China
ProdList
10319
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52849
Advantage
58
XI'AN TIANGUANGYUAN BIOTECH CO., LTD.
Tel
+86-029-86333380 18829239519
Fax
188 2923 9519
Email
sales06@tgybio.com
Country
China
ProdList
902
Advantage
58
HONG KONG IPURE BIOLOGY CO.,LIMITED
Tel
86 18062405514 18062405514
Email
ada@ipurechemical.com
Country
CHINA
ProdList
3461
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-6139-8061 +86-86-13650506873
Email
sales@chemdad.com
Country
China
ProdList
39894
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49374
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 13675144456
Fax
025-85563444
Email
sean.lv@synzest.com
Country
China
ProdList
11438
Advantage
58
Shanghai Universal Biotech Co.,Ltd
Tel
13774214275
Email
zhouzz@univ-bio.com
Country
China
ProdList
24990
Advantage
58
Changzhou Bojia Biomedical Technology Co., Ltd.
Tel
2122619822
Email
czbjpharma@126.com
Country
China
ProdList
18478
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
Advantage
58
Hubei Wanye Zhongcheng Chemical Reagent Co., Ltd.
Tel
18671296875 18671296875
Email
1205035102@qq.com
Country
China
ProdList
4303
Advantage
58
Shanghai Easy CDMO Co.,Ltd
Tel
021-61734564
Email
August@easycdmo.com
Country
China
ProdList
10030
Advantage
58
Cato Research Chemicals Inc.
Tel
13342851930
Email
3008394369@qq.com
Country
China
ProdList
15726
Advantage
58
Minglong (Xianning) Pharmaceutical Co., LTD
Tel
155-7155-6913 15571556913
Email
354024111@qq.com
Country
China
ProdList
2596
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Email
sales@coreychem.com
Country
China
ProdList
29882
Advantage
58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
Tel
+8613817748580
Fax
021-50175322
Email
cooperation@kean-chem.com
Country
China
ProdList
40066
Advantage
58
Henan Fengda Chemical Co., Ltd
Tel
+86-371-86557731 +86-13613820652
Fax
86-0371-86557731
Email
info@fdachem.com
Country
China
ProdList
20287
Advantage
58
LEAPCHEM CO., LTD.
Tel
+86-852-30606658
Email
market18@leapchem.com
Country
China
ProdList
43340
Advantage
58
GIHI CHEMICALS CO.,LIMITED
Tel
+8618058761490
Email
info@gihichemicals.com
Country
China
ProdList
49979
Advantage
58
PT CHEM GROUP LIMITED
Tel
Email
peter68@ptchemgroup.com
Country
China
ProdList
35425
Advantage
58
XI'AN TIANGUANGYUAN BIOTECH CO., LTD.
Tel
Country
China
ProdList
995
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
Shanghai Chongda Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@chongdachem.com
Country
CHINA
ProdList
18
Advantage
58
Taizhou Crene Chempharm Co., Ltd.
Tel
--
Fax
--
Email
sales@pharm-intermediates.com
Country
China
ProdList
596
Advantage
35
More
Less

View Lastest Price from 17-PHENYL TRINOR PGF2ALPHA-IPR manufacturers

Career Henan Chemical Co
Product
17-PHENYL TRINOR PGF2ALPHA-IPR 130209-76-6
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200KG
Release date
2019-07-01

130209-76-6, 17-PHENYL TRINOR PGF2ALPHA-IPRRelated Search:

(Z)-7-[(1R,2R,3R,5S)-3,5-DIHYDROXY-2-((E)-(S)-3-HYDROXY-5-PHENYL-PENT-1-ENYL)-CYCLOPENTYL]-HEPT-5-ENOIC ACID METHYL ESTER 17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA 17-PHENYL TRINOR PGF2ALPHA-IPR

  • 17-phenyl-18,19,20-trinor-prostaglandinf2alpha-1-isopropylester
  • 9ALPHA,11ALPHA,15S-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER
  • 17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER
  • 17-PHENYL TRINOR PGF2ALPHA-IPR
  • (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-5-heptenoic acid propan-2-yl ester
  • 7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic acid 1-methylethyl ester
  • Bimatoprost isopropyl ester
  • 17-phenyl trinor Prostaglandin F2α isopropyl ester
  • 17-phenyl trinor PGF2α isopropyl ester
  • isopropyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enoate
  • propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoate
  • Bimatoprost isopropyl este
  • imatoprost isopropyl ester
  • 17-phenyl trinor PGF2alpha isopropyl ester
  • Bimatoprost Acid Isopropyl Ester
  • 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)-
  • 13-trans-Latanoprost
  • isopropyl phenylhydroxypentene dihydroxycyclopentylheptenate
  • 17-phenyl trinor Prostaglandin F2α isopropyl ester
  • Sparsentan Impurity 17
  • 130209-76-6
  • C26H38O5