ChemicalBook > CAS DataBase List > 2,4-DICHLOROPHENETHYL ALCOHOL

2,4-DICHLOROPHENETHYL ALCOHOL

Product Name
2,4-DICHLOROPHENETHYL ALCOHOL
CAS No.
81156-68-5
Chemical Name
2,4-DICHLOROPHENETHYL ALCOHOL
Synonyms
2-(2,4-dichlorophenyl)ethan-1-ol;2,4-Dichlorobenzeneethanol;2-(2,4-DICHLOROPHENYL)ETHANOL;2,4-DICHLOROPHENETHYL ALCOHOL;Benzeneethanol, 2,4-dichloro-;2-(2,4-Dichlorophenyl)ethanol>2,4-Dichlorophenethyl alcohol 97%;2,4-Dichlorophenethyl alcohol,98%;2,4-Dichlorophenethyl alcohol, 98% 5GR
CBNumber
CB2419798
Molecular Formula
C8H8Cl2O
Formula Weight
191.05
MOL File
81156-68-5.mol
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2,4-DICHLOROPHENETHYL ALCOHOL Property

Boiling point:
119 °C/0.8 mmHg (lit.)
Density 
1.321 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.566(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
pka
14.57±0.10(Predicted)
form 
Liquid
Specific Gravity
1.321
color 
Clear colorless
CAS DataBase Reference
81156-68-5
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29062990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
394556
Product name
2,4-Dichlorophenethyl alcohol
Purity
97%
Packaging
1g
Price
$32.9
Updated
2023/01/07
Sigma-Aldrich
Product number
394556
Product name
2,4-Dichlorophenethyl alcohol
Purity
97%
Packaging
5g
Price
$66
Updated
2023/01/07
TCI Chemical
Product number
D2921
Product name
2-(2,4-Dichlorophenyl)ethanol
Purity
>97.0%(GC)
Packaging
5g
Price
$49
Updated
2025/07/31
TRC
Product number
D435568
Product name
2,4-Dichlorophenethyl alcohol
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
D435568
Product name
2,4-Dichlorophenethyl alcohol
Packaging
50mg
Price
$45
Updated
2021/12/16
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2,4-DICHLOROPHENETHYL ALCOHOL Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

General Description

2,4-Dichlorophenethyl alcohol is a phenethyl alcohol derivative. Its selective electrocatalytic dehalogenation over Pd-loaded felt cathode has been investigated.

Synthesis

50-00-0

94-99-5

81156-68-5

The general procedure for the synthesis of 2,4-dichlorophenethyl alcohol from formaldehyde and 2,4-dichlorobenzyl chloride is as follows: a two-necked Schlenk flask equipped with a magnetic stirring bar and a septum is heated under high vacuum with a hot air gun (ca. 400 °C) for 10 minutes. After cooling to room temperature, the flask was rinsed three times with argon. Zinc powder (654 mg, 2.0 equiv, 10.0 mmol) and THF (20 mL) were added sequentially. 1,2-Dibromoethane (5 mol%) was added and the reaction mixture was heated to boiling. After cooling to room temperature, chlorotrimethylsilane (1 mol%) was added and the mixture was again heated to boiling. After cooling to room temperature again, a solution of 2,4-dichlorobenzyl chloride (633 mg, 5.0 mmol, 1 eq.) in THF (10 mL) was added and the reaction mixture was heated at 70 °C for 2 hours and then cooled to room temperature. Paraformaldehyde (450 mg, 3.0 eq., 15.0 mmol) was slowly added at room temperature and the flask was heated again at 70 °C for 6 hours. After completion of the reaction, the solution was cooled to room temperature and saturated NH4Cl solution was added. The organic and aqueous phases were separated and the aqueous phase was extracted with ethyl acetate (100 mL). The organic layers were combined and washed sequentially with water (20 mL) and brine (10 mL), then dried with Na2SO4. The solvent was evaporated under reduced pressure and the residue was purified by silica gel column chromatography using cyclohexane or cyclohexane/ethyl acetate as eluent to afford 2,4-dichlorobenzeneethanol (510 mg, 83% yield) as a colorless liquid.

References

[1] Synthetic Communications, 2017, vol. 47, # 10, p. 968 - 974

2,4-DICHLOROPHENETHYL ALCOHOL Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-DICHLOROPHENETHYL ALCOHOL Suppliers

Lizet Chemical (Wuxi) Co., Ltd.
Tel
0510-85165022 18626399672
Email
sales@lizetchem.com
Country
China
ProdList
141
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58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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Energy Chemical
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021-021-58432009 400-005-6266
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021-58436166
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sales8178@energy-chemical.com
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China
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
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0573-85285100
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isenchem@163.com
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China
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9310
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Nanjing Chemlin Chemical Co., Ltd
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025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
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64
Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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info@hanhongsci.com
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China
ProdList
42934
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Shandong Xiya Chemical Co., Ltd
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4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
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China
ProdList
18729
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57
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View Lastest Price from 2,4-DICHLOROPHENETHYL ALCOHOL manufacturers

Career Henan Chemical Co
Product
2,4-DICHLOROPHENETHYL ALCOHOL 81156-68-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-24

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