Methyl 2,4-dichlorophenylacetate
- Product Name
- Methyl 2,4-dichlorophenylacetate
- CAS No.
- 55954-23-9
- Chemical Name
- Methyl 2,4-dichlorophenylacetate
- Synonyms
- 47339;2,4-dcaa methyl ester;4-dichlorophenylacetate;METHYL 2,4-DICHLOROPHENYLACETATE;Methyl 2,4-dichlorobenzeneacetate;Methyl2,4-Dichlorophenylacetate>Methyl 2-(2,4-dichlorophenyl)acetate;Methyl 2,4-dichlorophenylacetate,99%;2,4-Dimethyl acetic acid methyl ester;methyl 2,4-dichlorophenylacetate solution
- CBNumber
- CB5191785
- Molecular Formula
- C9H8Cl2O2
- Formula Weight
- 219.06
- MOL File
- 55954-23-9.mol
Methyl 2,4-dichlorophenylacetate Property
- Boiling point:
- 153°C/27mmHg(lit.)
- Density
- 1.3295 (rough estimate)
- refractive index
- 1.539-1.542
- storage temp.
- Sealed in dry,Room Temperature
- form
- Liquid
- color
- Clear colorless to yellow
- CAS DataBase Reference
- 55954-23-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn,N,F
- Risk Statements
- 22-67-65-62-51/53-48/20-38-11-66-36/38-36
- Safety Statements
- 24/25-62-61-36/37-33-29-16-9-26
- RIDADR
- UN 2810 6.1/PG 3
- HS Code
- 29163900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H319Causes serious eye irritation
H336May cause drowsiness or dizziness
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- M2528
- Product name
- Methyl 2,4-Dichlorophenylacetate
- Purity
- >99.0%(GC)
- Packaging
- 5g
- Price
- $40
- Updated
- 2025/07/31
- Product number
- M2528
- Product name
- Methyl 2,4-Dichlorophenylacetate
- Purity
- >99.0%(GC)
- Packaging
- 25g
- Price
- $120
- Updated
- 2025/07/31
- Product number
- M301395
- Product name
- Methyl 2,4-Dichlorophenylacetate
- Packaging
- 2.5g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 2723-5-17
- Product name
- Methyl 2,4-dichlorophenylacetate
- Purity
- 97%
- Packaging
- 100g
- Price
- $136
- Updated
- 2021/12/16
- Product number
- F832
- Product name
- Methyl 2,4-Dichlorophenylacetate
- Packaging
- 500g
- Price
- $360
- Updated
- 2021/12/16
Methyl 2,4-dichlorophenylacetate Chemical Properties,Usage,Production
Chemical Properties
clear colorless to yellow liquid
Synthesis
67-56-1
19719-28-9
55954-23-9
General procedure for the synthesis of methyl 2,4-dichlorophenylacetate from methanol and 2,4-dichlorophenylacetic acid: to a solution of 2,4-dichlorophenylacetic acid (3.5 g, 17.1 mmol) in methanol (100 mL) was slowly added concentrated sulfuric acid (20 drops). The reaction mixture was heated to reflux for 12 hours. Upon completion of the reaction, the solvent was removed by rotary evaporator under reduced pressure. The residue was diluted with cold water (50 mL) and extracted with ethyl acetate (3 x 50 mL). The organic layers were combined and washed sequentially with saturated sodium bicarbonate solution (50 mL) and saturated saline (50 mL), then dried with anhydrous sodium sulfate and filtered. The solvent was again removed by rotary evaporator under reduced pressure to obtain the crude product. The crude product was purified by silica gel column chromatography (eluent ratio 4:1 hexane/ethyl acetate) to afford methyl 2,4-dichlorophenylacetate (3.56 g, 95% yield) as a clear oil. The structure of the product was confirmed by 1H NMR (DMSO-d6): δ 7.40 (s, 1H), 7.22 (d, J=1.5 Hz, 2H), 3.74 (s, 2H), 3.71 (s, 3H).
References
[1] Bioorganic and Medicinal Chemistry, 2003, vol. 11, # 13, p. 2843 - 2866
[2] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 1, p. 245 - 249
[3] Patent: US2016/31892, 2016, A1. Location in patent: Paragraph 0195-0196
[4] ACS Medicinal Chemistry Letters, 2010, vol. 1, # 4, p. 145 - 149
[5] Bulletin of the Korean Chemical Society, 2010, vol. 31, # 8, p. 2315 - 2321
Methyl 2,4-dichlorophenylacetate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl 2,4-dichlorophenylacetate manufacturers
- Product
- Methyl 2,4-dichlorophenylacetate 55954-23-9
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-15
- Product
- Methyl (2,4-dichlorophenyl)acetate 55954-23-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-25