6-[(phenylsulfanyl)methyl]-2-sulfanylpyrimidin-4-ol

Product Name: 6-[(phenylsulfanyl)methyl]-2-sulfanylpyrimidin-4-ol
CAS No.: 189057-68-9
Chemical Name: 6-[(phenylsulfanyl)methyl]-2-sulfanylpyrimidin-4-ol
Synonyms: ZINC05626394;ZINC05626394 >=98% (HPLC);6-[(phenylsulfanyl)methyl]-2-sulfanylpyrimidin-4-ol;4(1H)-Pyrimidinone, 2,3-dihydro-6-[(phenylthio)methyl]-2-thioxo-
CBNumber: CB24198516
Molecular Formula: C11H10N2OS2
Formula Weight: 250.34
MOL File: 189057-68-9.mol

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6-[(phenylsulfanyl)methyl]-2-sulfanylpyrimidin-4-ol Property

Density: 1.40±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: 25mg/mL, clear
pka: 7.32±0.20(Predicted)
form: powder
color: white to beige

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1568
Product name: ZINC05626394
Purity: ≥98% (HPLC)
Packaging: 5 mg
Price: $94.4
Updated: 2025/07/31

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6-[(phenylsulfanyl)methyl]-2-sulfanylpyrimidin-4-ol Chemical Properties,Usage,Production

Description

ZINC05626394 is a Cytochrome b5 reductase 3 (CYB5R3) inhibitor. It acts by increasing NO bioavailability.

Uses

ZINC05626394 is a cytochrome b5 reductase 3 inhibitor with activity by increasing nitric oxide bioavailability. ZINC05626394 may have potential applications in anti-cancer suppression, especially in combination with antibody drug conjugates (ADCs) and immune checkpoint inhibitors. The efficacy of ZINC05626394 may be limited by different mechanisms, including antigen-related resistance and failure of endocytosis[1].

References

[1] Mechanisms of Resistance to Antibody-Drug Conjugates DOI:10.1074/jbc.M114.629964

6-[(phenylsulfanyl)methyl]-2-sulfanylpyrimidin-4-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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6-[(phenylsulfanyl)methyl]-2-sulfanylpyrimidin-4-ol Suppliers

China 3 United Kingdom 1 United States 2 Global 6

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

TargetMol Chemicals Inc.

Tel: +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 19962
Advantage: 58

189057-68-9, 6-[(phenylsulfanyl)methyl]-2-sulfanylpyrimidin-4-olRelated Search:

ZINC13466751 6-hydroxy-3-methyl-5-(2-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)pyrimidine-2,4(1H,3H)-dione N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)propanamide 3-Thiophenecarboxylic acid, 5-[[4-(carboxymethoxy)-3-methoxyphenyl]methylene]-2-[(4-ethoxyphenyl)amino]-4,5-dihydro-4-oxo-, 3-ethyl ester (5Z)-2-hydroxy-4-methyl-6-oxo-5-[(5-phenylfuran-2-yl)methylidene]-5,6-dihydropyridine-3-carbonitrile Benzamide, 4-[2-[1,5-dihydro-1-(4-nitrophenyl)-5-oxo-3-phenyl-4H-pyrazol-4-ylidene]hydrazinyl]- N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetamide ZINC03129319

6-[(phenylsulfanyl)methyl]-2-sulfanylpyrimidin-4-ol

ZINC05626394 >=98% (HPLC)

ZINC05626394

4(1H)-Pyrimidinone, 2,3-dihydro-6-[(phenylthio)methyl]-2-thioxo-

189057-68-9