N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetamide

Product Name: N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetamide
CAS No.: 904514-73-4
Chemical Name: N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetamide
Synonyms: ZINC08792229;ZINC08792229,ZINC-08792229;N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetamide;Acetamide, N-[2-(1H-indol-3-yl)ethyl]-2-[(9-oxo-9H-benz[c]indolo[3,2,1-ij][1,5]naphthyridin-5-yl)oxy]-
CBNumber: CB34091272
Molecular Formula: C30H22N4O3
Formula Weight: 486.53
MOL File: 904514-73-4.mol

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N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetamide Property

Boiling point:: 804.1±65.0 °C(Predicted)
Density: 1.42±0.1 g/cm3(Predicted)
pka: 14.59±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetamide Chemical Properties,Usage,Production

Uses

ZINC08792229 is a potent SIRT1 inhibitor. ZINC08792229 has the potential for research on SIRT1 related diseases, such as ageing, diabetes, cancers[1].

IC 50

SIRT1

References

[1] Yunan Sun, et al. Ligand-based virtual screening and inductive learning for identification of SIRT1 inhibitors in natural products. Sci Rep. 2016 Jan 25:6:19312. DOI:10.1038/srep19312

N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetamide Suppliers

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904514-73-4, N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetamideRelated Search:

ZINC13466751 6-hydroxy-3-methyl-5-(2-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)pyrimidine-2,4(1H,3H)-dione N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)propanamide 3-Thiophenecarboxylic acid, 5-[[4-(carboxymethoxy)-3-methoxyphenyl]methylene]-2-[(4-ethoxyphenyl)amino]-4,5-dihydro-4-oxo-, 3-ethyl ester (5Z)-2-hydroxy-4-methyl-6-oxo-5-[(5-phenylfuran-2-yl)methylidene]-5,6-dihydropyridine-3-carbonitrile Benzamide, 4-[2-[1,5-dihydro-1-(4-nitrophenyl)-5-oxo-3-phenyl-4H-pyrazol-4-ylidene]hydrazinyl]- ZINC03129319 6-[(phenylsulfanyl)methyl]-2-sulfanylpyrimidin-4-ol

N-(2-(1H-indol-3-yl)ethyl)-2-((8-oxo-8H-benzo[c]indolo[3,2,1-ij][1,5]naphthyridin-12-yl)oxy)acetamide

Acetamide, N-[2-(1H-indol-3-yl)ethyl]-2-[(9-oxo-9H-benz[c]indolo[3,2,1-ij][1,5]naphthyridin-5-yl)oxy]-

ZINC08792229

ZINC08792229,ZINC-08792229

904514-73-4